Lifeboat Foundation

A number of companies are studying and commercializing rapamycin and rapalogs, including resTORbio, a Boston-based company. Tam Hunt got in touch with Dr. Joan Mannick from the company to find out more about this promising anti-aging therapeutic.

Blagoskonny ([3], [4]) has suggested that rapamycin and rapalogs are effective anti-aging therapies today for humans as well as other animals because they arrest “quasi-programmed hypertrophy.” What are your thoughts on Blagoskonny’s theory?

I think Blagoskonny’s theory is very interesting. mTOR stimulates cell growth, and there is data that mTOR becomes hyperactive in some aging tissues. This may explain why TORC1 inhibitors have benefit in aging-related diseases.

Continue reading “An Interview with Dr. Joan Mannick of resTORbio” »

We have known since the 19th century that young blood has surprising curative and rejuvenation abilities. It’s quite strange, but it happens to be true. In recent years, scientific efforts to understand what it is about young blood that causes rejuvenation have ramped up.

We now know that young and old mice with surgically connected circulatory systems will experience altered aging: the young mouse will prematurely grow old, and the old mouse will, in many cases, miraculously grow young. This is known as heterochronic parabiosis, and it is a large source of the legitimate excitement about the potential of young plasma to lead to human rejuvenation [1].

The challenge, of course, is how to achieve these benefits in more acceptable and less disturbing ways.

Continue reading “An Interview with Dr. Steven Braithwaite of Alkahest” »

Allison Duettmann challenges Aubrey De Grey with the top objections against longevity to be debunked and debated before opening up the floor to the public.

Aubrey de Grey, Ph.D.

Continue reading “Longevity Myth Busting — Aubrey de Grey” »

Environmentalism and climate change are increasingly being pushed on us everywhere, and I wanted to write the transhumanism and life extension counter argument on why I prefer new technology over nature and sustainability. Here’s my new article:

On a warming planet bearing scars of significant environmental destruction, you’d think one of the 21st Century’s most notable emerging social groups—transhumanists—would be concerned. Many are not. Transhumanists first and foremost want to live indefinitely, and they are outraged at the fact their bodies age and are destined to die. They blame their biological nature, and dream of a day when DNA is replaced with silicon and data.

Their enmity of biology goes further than just their bodies. They see Mother Earth as a hostile space where every living creature—be it a tree, insect, mammal, or virus—is out for itself. Everything is part of the food chain, and subject to natural law: consumption by violent murder in the preponderance of cases. Life is vicious. It makes me think of pet dogs and cats, and how it’s reported they sometimes start eating their owner after they’ve died.

Continue reading “Environmentalists are Wrong: Nature Isn’t Sacred and We Should Replace It” »

Guest writer Dr. Asimina Pantazi gives her impressions of the recent Berlin Undoing Aging Conference from the point of view of someone working in research.

As a millennial with limited orientation abilities but expertise with digital tools, I used Google Maps to find the venue, fearing that I would have no data and would get lost in Berlin, only to find out that I was only a couple of meters away from to the venue entrance.

The Undoing Aging 2019 conference took place on May 28–30 at Umspannwerk Alexanderplatz: a multi-level industrial setting, with metal stairs, funky lights, and a balcony overlooking the minimal conference hall. This gave me my first positive vibes.

Continue reading “Undoing Aging 2019: Highlights and Impressions” »

Presents its list of the top 30 FemTech Influencers, whose efforts in the FemTech Healthcare, FemTech Preventive Medicine and FemTech Longevity sectors have helped to grow the industry to its current state of maturity.

Jill Angelo genneve Elina Berglund Natural Cycles Starling Bank Tania Boler Elvie Ghela Boskovich Judith Campisi Adia Femtech Collective Dame Products EMBR Robin Starbuck Farmanfarmaian Cora Lifestyle Angie Lee Janet Lieberman Nuala Murphy Moment.Health Elena Mustatea Bold Health Anastasia Georgievskaya Haut.AI Maven Clinic THINX Nicole Shanahan Clearaccessip, Inc. Tammy Sun Ida Tin

Link to the Report: https://www.aginganalytics.com/femtech-healthcare-q1-2019

Continue reading “Aging Analytics Agency Photo 4” »

When NASA set out to study identical twin astronauts, leaving one on Earth and sending the other to the International Space Station (ISS) for a year, they expected that the rigours of microgravity would have largely negative impacts.

But on board the ISS, Scott Kelly, 51, underwent a very strange transformation which has left scientists scratching their heads.

The telomeres in his white blood cells got longer. Telomeres are the protective caps which sit at the end of chromosomes, protecting the DNA inside, like the plastic aglets on the end of shoelaces.

Continue reading “Strange anti-ageing effect of space travel discovered in NASA’s Twin Study” »

Scientists from the University of Maryland have identified four species that have ‘extreme longevity’ and say their adaptations could let humans live up to 240 years old.