Reducing calorie intake helps cancer-fighting immune cells do their jobs more effectively, reports a study by Van Andel Institute scientists and collaborators. The findings lay the groundwork for developing dietary strategies to boost the effects of a powerful class of cancer immunotherapies.
“Growing evidence suggests dietary restriction has anti-cancer effects but the ‘why and how’ are not well understood. Our new study reveals one way this relationship may work: by providing T cells, the soldiers of the immune system, with the right mix of nutrients to more effectively fight cancer,” said Russell Jones, Ph.D., chair of VAI’s Department of Metabolism and Nutritional Programming and corresponding author of the study.
“Additional research is needed but we are hopeful these insights can inform evidence-based dietary guidelines to improve the effectiveness of immune-based cancer treatments.”







