Test your clinical reasoning with this case of a 41-year-old man presenting with right foot tingling.
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Category: security
Elicited Repetitive Daily Blindness Associated With Gain-of-Function SCN1A Variants and Responsiveness to Sodium Channel Blockers
Study demonstrates that elicited repetitive daily blindness is a clinical feature in patients with familial hemiplegic migraine 3 because of gain-of-function Nav1.1 variants. Patients in this report responded to sodium channel blocker medications.
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Phosphoinositide Depletion and Compensatory Phospho-Signaling in Angiotensin II-Induced Heart Disease
Westhoff & colleagues found that PTEN inhibition reduces cardiac fibrosis caused by the high blood pressure hormone AngII. Learn how to fight fibrosis from hypertension at.
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Efficacy and Safety of VMAT2 Inhibitors in the Treatment of Huntington DiseaseA Meta-Analysis of Randomized Clinical Trials
In patients with Huntington disease, vesicular monoamine transporter 2 inhibitors (VMAT2is) treatment improved chorea without significant changes in adverse effects or depressive symptoms.
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Influence of Decreased Kidney Function on Plasma Biomarkers of Neurodegenerative Disorders in Routine Care: Confirmation of the Interest of Ratios
This study found that impaired kidney function was linked to increased plasma cerebral amyloidosis biomarkers, but ratio-based measures showed stable sensitivity and specificity for detecting cerebral amyloidosis across all eGFR groups.
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