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Apical periodontitis, a chronic and hard-to-treat dental infection, affects more than half of the population worldwide and is the leading cause of tooth loss. Root canal is the standard treatment, but existing approaches to treat the infection have many limitations that can cause complications, leading to treatment failure.

Now, researchers at the School of Dental Medicine, Perelman School of Medicine, and School of Engineering and Applied Sciences have identified a promising new therapeutic option that could potentially disrupt current treatments. The team of researchers is part of the Center for Innovation & Precision Dentistry, a joint research center between Penn Dental Medicine and Penn Engineering that leverages engineering and computational approaches to advance oral and craniofacial health care innovation.

In a paper published in the Journal of Clinical Investigation, they show that ferumoxytol, an FDA-approved iron oxide nanoparticle formulation, greatly reduces infection in patients diagnosed with apical periodontitis.

SpaceX’s Starship is poised for its eighth flight from Boca Chica, Texas, pending regulatory approval from the FAA. The previous flight resulted in a mid-air explosion, leading to increased scrutiny and a temporary suspension by the FAA. The upcoming launch will feature a daring maneuver to catch the booster stage with “chopstick” arms, showcasing advanced engineering feats. The mission aims to deploy Starlink simulators, marking progress toward new satellite technology. Elon Musk and SpaceX view Starship as crucial for future missions to Mars and the Moon, with NASA keenly following its progress.

Riverworld.


Imagine a world stretched along a single, endless river inside a colossal space megastructure. Explore the fascinating concept of the Topopolis, a futuristic habitat billions of miles long, where humanity might thrive in a sprawling civilization bound by physics, engineering, and imagination.

Watch my exclusive video Big Alien Theory https://nebula.tv/videos/isaacarthur–… Nebula using my link for 40% off an annual subscription: https://go.nebula.tv/isaacarthur Get a Lifetime Membership to Nebula for only $300: https://go.nebula.tv/lifetime?ref=isa… Use the link gift.nebula.tv/isaacarthur to give a year of Nebula to a friend for just $30. Visit our Website: http://www.isaacarthur.net Join Nebula: https://go.nebula.tv/isaacarthur Support us on Patreon: / isaacarthur Support us on Subscribestar: https://www.subscribestar.com/isaac-a… Facebook Group: / 1,583,992,725,237,264 Reddit: / isaacarthur Twitter: / isaac_a_arthur on Twitter and RT our future content. SFIA Discord Server: / discord Credits: Topopolis: The Eternal River Episode 487a; February 23, 2025 Written, Produced & Narrated by: Isaac Arthur Graphics: Apogii.uk, Ken York YD Visual, Steve Bowers, Udo Scroeter Select imagery/video supplied by Getty Images Music Courtesy of Epidemic Sound http://epidemicsound.com/creator.

This approach is not only faster and more energy-efficient but also delivers precise control over the material’s optical properties.

Light-Powered Quantum Dot Tuning

Researchers at north carolina state university.

Founded in 1887 and part of the University of North Carolina system, North Carolina State University (also referred to as NCSU, NC State, or just State) is a public land-grant research university in Raleigh, North Carolina. NC State offers a wide range of academic programs and disciplines, including the humanities, social sciences, natural sciences, engineering, business, and education. It is known for its strong programs in engineering, science, and technology and is a leader in research and innovation. It forms one of the corners of the Research Triangle together with Duke University in Durham and The University of North Carolina at Chapel Hill.

Traditional 3D printing builds objects layer by layer, but tomographic volumetric additive manufacturing (TVAM) takes a different approach. It uses laser light to illuminate a rotating vial of resin, solidifying material only where the accumulated energy surpasses a specific threshold. A key advantage of TVAM is its speed—it can produce objects in seconds, whereas conventional layer-based 3D printing takes about 10 minutes. However, its efficiency is a major drawback, as only about 1% of the projected light contributes to forming the intended shape.

Researchers from EPFL’s Laboratory of Applied Photonic Devices, led by Professor Christophe Moser, and the SDU Centre for Photonics Engineering, led by Professor Jesper Glückstad, have developed a more efficient TVAM technique, as reported in Nature Communications

<em> Nature Communications </em> is an open-access, peer-reviewed journal that publishes high-quality research from all areas of the natural sciences, including physics, chemistry, Earth sciences, and biology. The journal is part of the Nature Publishing Group and was launched in 2010. “Nature Communications” aims to facilitate the rapid dissemination of important research findings and to foster multidisciplinary collaboration and communication among scientists.

UK-based Core Power has announced that it plans to mass produce a fleet of floating nuclear power plants (FNPPs) using advanced reactor design and modular shipbuilding to be anchored off the US coast in about 10 years.

Nuclear power is enjoying something of a renaissance with many countries turning to the atom to meet their energy needs. However, the bottleneck for increasing the nuclear sector isn’t with manufacturing reactors. It’s the civil engineering side of things, with most of the time and cost going to securing real estate for building the foundations and buildings for the plant as well as navigating a bewildering maze of permits, licenses, and planning permissions.

To get around this as well as speed up production, Core Power plans to use Generation 4 reactor design combined with conventional modular shipbuilding methods to crank out floating nuclear plants on an assembly line basis. To reflect this, the company is referring to this as the “Liberty program” in a call back to the famous Liberty ships of the Second World War that were built at a speed of as fast as four days for one hull.

Researchers have developed a high-resolution embedded 3D-printing technique that enables the fabrication of ultra-fine fibers, mimicking nature’s structures. Using a solvent exchange process, they achieved unprecedented resolutions of 1.5 microns, unlocking new possibilities for bioinspired materials and advanced engineering applications.

Researchers have been exploring new methods to produce and replicate the diverse and valuable features found in nature. Fine hairs and fibers, which are ubiquitous in the natural world, serve various purposes, from sensory functions to contributing to the unique consistency of hagfish slime.

MechSE Professors Sameh Tawfick and Randy Ewoldt, along with doctoral candidate M. Tanver Hossain and external collaborators, have addressed this need using their advanced embedded 3D-printing technique, recently published in Nature Communications.

Finding the right lubricant for the right purpose is a task that is often extremely important in industry. Not only to reduce friction, overheating and wear, but also to save energy. At TU Wien, the research groups of Prof Carsten Gachot (Tribology, Mechanical Engineering) and Prof Dominik Eder (Chemistry) are therefore working together to develop innovative, improved lubricants.

The team has now presented a new type of material with special properties: The lubricant COK-47 is not liquid like lubricating oil, but a powdery solid substance. On a nanoscale, it consists of stacks of atomically thin sheets, like a tiny stack of cards.

When the material comes into contact with , these platelets can slide past each other very easily—a so-called tribofilm is created, which ensures extremely low . This makes COK-47 a highly interesting in .

Researchers have developed a freely available droplet microfluidic component library, which promises to transform the way microfluidic devices are created. This innovation, based on low-cost rapid prototyping and electrode integration, makes it possible to fabricate microfluidic devices for under $12 each, with a full design-build-test cycle completed within a single day. The components are biocompatible, high-throughput, and capable of performing multistep workflows, such as droplet generation, sensing, sorting, and anchoring, all critical for automating microfluidic design and testing.

Microfluidics, particularly droplet-based systems, has become a promising technology for diverse fields, including protein engineering, single-cell sequencing, and nanoparticle synthesis. However, the traditional methods of fabricating —typically using PDMS (polydimethylsiloxane)—are time-consuming and costly, often requiring cleanroom facilities or external vendors.

While alternatives like laser cutting and 3D printing have been explored, these methods often suffer from limitations in resolution, material compatibility, and scalability. As a result, there has been an urgent need for a more efficient, cost-effective, and accessible fabrication method to help propel innovation in microfluidic technology.

Researchers at North Carolina State University have demonstrated a new technique that uses light to tune the optical properties of quantum dots—making the process faster, more energy-efficient and environmentally sustainable—without compromising material quality.

The findings are published in the journal Advanced Materials.

“The discovery of quantum dots earned the Nobel Prize in chemistry in 2023 because they are used in so many applications,” says Milad Abolhasani, corresponding author of a paper on the work and ALCOA Professor of Chemical and Biomolecular Engineering at NC State. “We use them in LEDs, , displays, quantum technologies and so on. To tune their , you need to tune the bandgap of quantum dots—the minimum energy required to excite an electron from a bound state to a free-moving state—since this directly determines the color of light they emit.