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Archive for the ‘neuroscience’ category

Apr 11, 2024

This fMRI technique promised to transform brain research — why can no one replicate it?

Posted by in categories: biotech/medical, neuroscience

In conventional functional MRI (fMRI), researchers monitor changes in blood flow to different brain regions to estimate activity. But this response lags by at least one second behind the activity of neurons, which send messages in milliseconds.

Park and his co-authors said that DIANA could measure neuronal activity directly, which is an “extraordinary claim”, says Ben Inglis, a physicist at the University of California, Berkeley.

The DIANA technique works by applying minor electric shocks every 200 milliseconds to an anaesthetized animal. Between shocks, an MRI scanner collects data from one tiny piece of the brain every 5 milliseconds. After the next shock, another spot is scanned. The software stitches together data from all the spots, to visualize changes in an entire slice of brain over a 200-millisecond period. The process is similar to filming an action pixel by pixel, where the action would need to be repeated to record every pixel, and those recordings stitched together, to create a full video.

Apr 10, 2024

Dr. Phyllis Ferrell, DrPH, MBA — Chief Impact Officer, Alzheimer’s Moonshot, StartUp Health

Posted by in categories: biotech/medical, business, life extension, neuroscience

Is Chief Impact Officer for StartUp Health’s Alzheimer’s Moonshot (https://www.startuphealth.com/alzheimers), a new global initiative created to develop a collaborative innovation community alongside leading companies, research teams, and stakeholders, with a mission to accelerate progress in prevention, diagnosis, and management of Alzheimer’s disease and related dementias. With support from the Alzheimer’s Drug Discovery Foundation (ADDF) and Gates Ventures, StartUp Health is looking to break down silos and foster meaningful collaboration between mission-aligned founders, funders, and partners.

Dr. Ferrell also serves as Strategic Advisor, Davos Alzheimer’s Collaborative (https://www.davosalzheimerscollaborat…) which is building a global clinical trial network and technology platform that will link trial sites around the world.

Continue reading “Dr. Phyllis Ferrell, DrPH, MBA — Chief Impact Officer, Alzheimer’s Moonshot, StartUp Health” »

Apr 10, 2024

Certain household chemicals could pose a threat to brain health, research suggests

Posted by in categories: biotech/medical, chemistry, health, neuroscience

Cell and animal tests suggest two classes of common chemicals might play a role in neurological disease.

Apr 10, 2024

Editorial: Nanotechnologies in Neuroscience and Neuroengineering

Posted by in categories: engineering, health, internet, nanotechnology, neuroscience

2 Department of Neurobiology, Duke University, Durham, NC, United States.

3Center for Bioelectric Interfaces of the Institute for Cognitive Neuroscience, National Research University Higher School of Economics, Moscow, Russia.

4Department of Information and Internet Technologies of Digital Health Institute, I.M. Sechenov First Moscow State Medical University, Moscow, Russia.

Apr 10, 2024

Brain Acidity Linked With Multiple Neurological Disorders

Posted by in categories: biotech/medical, genetics, neuroscience

In a global research effort, scientists have uncovered a relationship between metabolism problems in the brain and a range of neuropsychiatric and neurodegenerative disorders, from autism to Alzheimer’s disease and more.

Despite their diverse symptoms, these conditions – as well as depression, epilepsy, schizophrenia, intellectual disability, and bipolar disorder – all involve a degree of cognitive impairment and often share genetic or metabolic features, hinting at a common biological basis.

The extensive collaboration by the International Brain pH Project Consortium, involving 131 scientists from 105 labs in seven countries, identified changes in brain acidity and lactate levels in animals as key signs of this metabolic dysfunction.

Apr 10, 2024

Connecting lab-grown brain cells provides insight into how our own brains work

Posted by in categories: biotech/medical, neuroscience

The idea of growing functioning human brain-like tissues in a dish has always sounded far-fetched, even to researchers in the field. Towards the future goal, a Japanese and French research team has developed a technique for connecting lab-grown brain-mimicking tissue in a way that resembles circuits in our brain.

The work appears in Nature Communications.

It is challenging to study exact mechanisms of the brain development and functions. Animal studies are limited by differences between species in and function, and grown in the lab tend to lack the characteristic connections of cells in the human brain. What’s more, researchers are increasingly realizing that these interregional connections, and the circuits that they create, are important for many of the brain functions that define us as humans.

Apr 10, 2024

Step steady: Consistent walking improves brain function in older adults

Posted by in categories: biotech/medical, life extension, neuroscience

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In a recent study published in the journal Scientific Reports, researchers explored how changes in daily step counts and variability affect cognitive function in older adults during a 10-week physical activity intervention.

Study: Association between changes in habitual stepping activity and cognition in older adults. Image Credit: SibRapid / Shutterstock.

Continue reading “Step steady: Consistent walking improves brain function in older adults” »

Apr 9, 2024

Traumatic Brain Injury

Posted by in category: neuroscience

(TBI) is a sudden injury that causes damage to the brain. It may happen when there is a blow, bump, or jolt to the head. This is a closed head injury. A TBI can also happen when an object penetrates the skull. This is a penetrating injury.

Symptoms of a TBI can be mild, moderate, or severe. Concussions are a type of mild TBI. The effects of a concussion can sometimes be serious, but most people completely recover in time. More severe TBI can lead to serious physical and psychological symptoms, coma, and even death.

Apr 9, 2024

Repotrectinib Shrinks ROS1-Positive NSCLC Tumors

Posted by in categories: biotech/medical, neuroscience

For many of these individuals, the response to repotrectinib lasted for several years.

“Repotrectinib can lead to long-term responses for patients with ROS1 fusion–positive lung cancers, including those who have and have not received prior targeted therapy,” said Alexander Drilon, M.D., of Memorial Sloan Kettering Cancer Center, who led the TRIDENT-1 study.

Treatment with repotrectinib also shrank tumors that had spread to the brain, a common location for lung metastases, the researchers reported.

Apr 9, 2024

Stuart Hameroff — Can Consciousness be Non-Biological?

Posted by in categories: biological, neuroscience

Register for free to get subscriber-only benefits: https://closertotruth.com/If consciousness is 100% physical, we would have to conclude that the same kind…

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