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Archive for the ‘neuroscience’ category

Jan 28, 2023

Special Vascular Cells Adjust Blood Flow in Brain Capillaries Based on Local Energy Needs

Posted by in categories: biotech/medical, neuroscience

Its impressive how adaptive the brain is to each situation. It can sense which portions of the brain need more blood flow depending on energy usage and makes the needed tiny adjustments.


Summary: Researchers identified a specific type of cell that sits on top of the brain’s smallest blood vessels that sense when their region of the brain is in need of energy.

Source: University of Maryland

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Jan 27, 2023

Even simple motions make ripples across brain, study finds

Posted by in category: neuroscience

Even a simple movement like pushing a button sends ripples of activity throughout networks of neurons spanning across the brain, new University of Oregon research shows.

The finding highlights just how complex the is, challenging the simplified textbook picture of distinct areas dedicated to specific functions.

“It’s really well known that that the primary motor cortex controls output,” said Alex Rockhill, a graduate student in the lab of human physiology professor Nicki Swann. “But there’s a lot more to movement than this one brain area.”

Jan 27, 2023

A drug that increases dopamine can reverse the effects of inflammation on the brain in depression, Emory study shows

Posted by in categories: biotech/medical, chemistry, neuroscience

𝐀 𝐝𝐫𝐮𝐠 𝐭𝐡𝐚𝐭 𝐢𝐧𝐜𝐫𝐞𝐚𝐬𝐞𝐬 𝐝𝐨𝐩𝐚𝐦𝐢𝐧𝐞 𝐜𝐚𝐧 𝐫𝐞𝐯𝐞𝐫𝐬𝐞 𝐭𝐡𝐞 𝐞𝐟𝐟𝐞𝐜𝐭𝐬 𝐨𝐟 𝐢𝐧𝐟𝐥𝐚𝐦𝐦𝐚𝐭𝐢𝐨𝐧 𝐨𝐧 𝐭𝐡𝐞 𝐛𝐫𝐚𝐢𝐧 𝐢𝐧 𝐝𝐞𝐩𝐫𝐞𝐬𝐬𝐢𝐨𝐧, 𝐄𝐦𝐨𝐫𝐲 𝐬𝐭𝐮𝐝𝐲 𝐬𝐡𝐨𝐰𝐬

𝘼𝙣 𝙀𝙢𝙤𝙧𝙮 𝙐𝙣𝙞𝙫𝙚𝙧𝙨𝙞𝙩𝙮 𝙨𝙩𝙪𝙙𝙮 𝙥𝙪𝙗𝙡𝙞𝙨𝙝𝙚𝙙 𝙞𝙣 𝙉𝙖𝙩𝙪𝙧𝙚’𝙨 𝙈𝙤𝙡𝙚𝙘𝙪𝙡𝙖𝙧 𝙋𝙨𝙮𝙘𝙝𝙞𝙖𝙩𝙧𝙮 𝙨𝙝𝙤𝙬𝙨 𝙡𝙚𝙫𝙤𝙙𝙤𝙥𝙖, 𝙖 𝙙𝙧𝙪𝙜 𝙩𝙝𝙖𝙩 𝙞𝙣𝙘𝙧𝙚𝙖𝙨𝙚𝙨 𝙙𝙤𝙥𝙖𝙢𝙞𝙣𝙚 𝙞𝙣 𝙩𝙝𝙚 𝙗𝙧𝙖𝙞𝙣, 𝙝𝙖𝙨 𝙥𝙤𝙩𝙚𝙣𝙩𝙞𝙖𝙡 𝙩𝙤 𝙧𝙚𝙫𝙚𝙧𝙨𝙚 𝙩𝙝𝙚 𝙚𝙛𝙛𝙚𝙘𝙩𝙨 𝙤𝙛 𝙞𝙣𝙛𝙡𝙖𝙢𝙢𝙖𝙩𝙞𝙤𝙣 𝙤𝙣 𝙗𝙧𝙖𝙞𝙣 𝙧𝙚𝙬𝙖𝙧𝙙 𝙘𝙞𝙧𝙘𝙪𝙞𝙩𝙧𝙮, 𝙪𝙡𝙩𝙞𝙢𝙖𝙩𝙚𝙡𝙮 𝙞𝙢𝙥𝙧𝙤𝙫𝙞𝙣𝙜 𝙨𝙮𝙢𝙥𝙩𝙤𝙣𝙨 𝙤𝙛 𝙙𝙚𝙥𝙧𝙚𝙨𝙨𝙞𝙤𝙣.

Numerous labs across the world have shown that inflammation causes reduced motivation and anhedonia, a core symptom of depression, by affecting the brain’s reward pathways.

Continue reading “A drug that increases dopamine can reverse the effects of inflammation on the brain in depression, Emory study shows” »

Jan 27, 2023

Daniel C. Dennett — What is Consciousness?

Posted by in category: neuroscience

Consciousness is what we can know best and explain least. It is the inner subjective experience of what it feels like to see red or smell garlic or hear Beethoven. Consciousness has intrigued and baffled philosophers. To begin, we must define and describe consciousness. What to include in a complete definition and description of consciousness?

Free access to Closer to Truth’s library of 5,000 videos: http://bit.ly/376lkKN

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Jan 27, 2023

Scientists find a drug that treats obesity, fatty liver, heart disease

Posted by in categories: biotech/medical, food, neuroscience

According to the U.S. Centers for Disease Control and Prevention, more than 40% of people living in the U.S. are obese; and 43% of American women over the age of 60—long past menopause—are considered obese. A recent Johns Hopkins study showed that a drug first developed to treat Alzheimer’s disease, schizophrenia, and sickle cell disease could treat obesity and fatty liver and improve heart function—without changes in food intake or daily activity.

Jan 27, 2023

Toward Singularity — Neuroscience Inspiring AI

Posted by in categories: education, neuroscience, robotics/AI, singularity

Takes a look at how neuroscience is inspiring the development of artificial intelligence. Our amazing brain, one of the most complicated systems we know about, is inspiring the development of intelligence machines. Machines that may well surpass our own intelligence and could birth a new species on the planet. Opportunity and danger lie beyond the singularity!

For those who purchase the video on Vimeo https://vimeo.com/ondemand/towardsingularity there are extended interviews that give further insight into biologically inspired AI technology.

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Jan 26, 2023

Neuroimaging study offers new insight into brain activity patterns linked to PTSD

Posted by in categories: biotech/medical, neuroscience

A new neuroimaging study showed that people suffering from posttraumatic stress disorder (PTSD) exhibited increased activation in the amygdala region of the brain when shown surprised and neutral facial expressions. The same phenomenon was observed in identical twins of these individuals who did not suffer from PTSD.

The study, which was published in the Journal of Psychiatric Research, sheds new light on the neural mechanisms underlying the development of PTSD.

PTSD is a condition that develops in approximately 20% of individuals exposed to psychological trauma in their lifetime. It is defined by wide clusters of symptoms that include intrusive memories, negative alterations in mood, heightened levels of arousal, and other symptoms. Currently, there are many treatment options available for PTSD; however, for some patients, the treatments offered do not provide clinical relief.

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Jan 26, 2023

Cognition after the representation war (part 2) — 4E Cognition

Posted by in categories: computing, neuroscience

Through the issue of mental representation addressed in the previous article, it is possible to get a first idea about the theoretical discontinuity between traditional cognitive science and more recent approaches gathered under the umbrella of so-called 4E Cognition. In fact, in many cases those latter reflect — directly or in a collateral way — the attempt to overcome the problem of representation in human cognition, even thought, as we’re going to say, this doesn’t entail a unite consensus at all.

4E Cognition has not to be seen as a specific and well-defined theoretical system, rather, it is a term referring to all those works (hypothesis, theories, experiments, etc.) which deviate from the traditional representational-computational model of cognition (see part 1), taking a dynamic and enactive approach, namely, conceiving cognition as embodied, embedded, enactive and extended (that’s why 4E). In a nutshell, mental states and cognitive processes would be: embodied when they are partly constituted by bodily processes; embedded when there is an essential causal dependence between such states and processes and the environment; enacted when the actions of the subject can partly constitute these states and processes; and extended when objects or processes in the environment can partly constitute those states and processes [4].

Here you can find a quick conversational introduction to 4E cognition made by professor Shaun Gallagher:

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Jan 26, 2023

My Anti-Aging Protocol Broke a World Record… — YouTube

Posted by in categories: biological, life extension, neuroscience

Bryan Johnson releases his rejuvenation protocol:


Blueprint is a public science experiment to determine whether it’s possible to stay the same biological age. This requires slowing down aging processes as much as possible and then reversing the aging that has happened. Currently my speed of aging is .76 (DunedinPACE). That means for every 365 days each year, I age 277 days. My goal is to remain the same age biologically for every 365 days that pass.

Continue reading “My Anti-Aging Protocol Broke a World Record… — YouTube” »

Jan 26, 2023

Twelve-hour rhythms in transcript expression within the human dorsolateral prefrontal cortex are altered in schizophrenia

Posted by in categories: biotech/medical, neuroscience

Twelve-hour (12 h) ultradian rhythms are a well-known phenomenon in coastal marine organisms. While 12 h cycles are observed in human behavior and physiology, no study has measured 12 h rhythms in the human brain. Here, we identify 12 h rhythms in transcripts that either peak at sleep/wake transitions (approximately 9 AM/PM) or static times (approximately 3 PM/AM) in the dorsolateral prefrontal cortex, a region involved in cognition. Subjects with schizophrenia (SZ) lose 12 h rhythms in genes associated with the unfolded protein response and neuronal structural maintenance. Moreover, genes involved in mitochondrial function and protein translation, which normally peak at sleep/wake transitions, peak instead at static times in SZ, suggesting suboptimal timing of these essential processes.

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