Researchers across 14 medical centers in China, including Peking University People’s Hospital, have found that an investigational drug, berberine ursodeoxycholate (HTD1801), significantly lowered blood sugar levels and improved metabolic and liver health in patients with type 2 diabetes (T2D). The findings and an invited commentary, both published in JAMA Network Open, suggest that HTD1801 could serve as a new oral treatment option for T2D and its related complications.
Researchers develop nanoscale 3D printing method to create biodegradable vaccine carriers with controlled release.
Researchers at NYU Abu Dhabi (NYUAD) have developed an innovative tool that enhances surgeons’ ability to detect and remove cancer cells during cryosurgery, a procedure that uses extreme cold to destroy tumors. This breakthrough technology involves a specialized nanoscale material that illuminates cancer cells under freezing conditions, making them easier to distinguish from healthy tissue and improving surgical precision.
Detailed in the study “Freezing-Activated Covalent Organic Frameworks for Precise Fluorescence Cryo-Imaging of Cancer Tissue” in the Journal of the American Chemical Society, the Trabolsi research group at NYUAD designed a unique nanoscale covalent organic framework (nTG-DFP-COF) that responds to extreme cold by increasing its fluorescence. This makes it possible to clearly differentiate between cancerous and healthy tissues during surgery.
The material, prepared by Gobinda Das, Ph.D., a researcher in the Trabolsi Research Group at NYUAD, is engineered to be biocompatible and low in toxicity, ensuring it interacts safely within the body. Importantly, it maintains its fluorescent properties even in the presence of ice crystals inside cells, allowing real-time monitoring during cryosurgery.
This method enables applications in photonics, electronics, and advanced materials for energy and environmental use.
This technique will control functional nanoparticle assembly into uniform monolayers over large surfaces.
Employing nanoparticle components is often challenging despite its versatility, especially when fabricating a device. Therefore, scientists presented an electrostatic assembly as a potential solution, where nanoparticles attach to oppositely charged surfaces.
However, this process can take a lot of work, and thus, the South Korean scientists devised the “mussel-inspired” one-shot nanoparticle assembly technique that transports materials from water in microscopic volumes to two-inch wafers in 10 seconds.
The researchers indicate that several challenges remain. The current system operates at cryogenic temperatures, which limits practical applications. While photons themselves can function at room temperature, the quantum dot requires cooling to maintain stability. Researchers are exploring alternative materials and designs that could allow operation at higher temperatures.
Additionally, the experiment used a single quantum dot, which is not easily scalable to large numbers of qubits needed for universal quantum computing. Future work will need to integrate multiple quantum dots or alternative photon sources that can be mass-produced with high consistency.
Another limitation is the reliance on superconducting detectors with an efficiency of 79%. If detection efficiency is improved beyond 93.7%, the overall system efficiency could surpass the required threshold even further. Advancements in superconducting nanowire technology suggest this is feasible in the near future.
This innovation sidesteps the usual size limitations, enabling strong signal reception despite its microscopic dimensions. With high tunability and real-world transmission tests proving its viability, the nano-antenna could transform communications in extreme environments.
Nano-enhanced perovskite solar cells last 10x longer by trapping iodine, paving the way for durable, affordable solar technology.
Stretchable display materials, which are gaining traction in the next-generation display market, have the advantage of being able to stretch and bend freely, but the limitations of existing materials have resulted in distorted screens and poor fit.
General elastomeric substrates are prone to screen distortion due to the “Poisson’s ratio” phenomenon, in which stretching in one direction causes the screen to shrink in the vertical direction. In particular, electronics that are in close contact with the skin, such as wearable devices, are at risk of wrinkling or pulling on the skin during stretching and shrinking, resulting in poor fit and performance.
A research team led by Dr. Jeong Gon Son of the Korea Institute of Science and Technology (KIST) and Professor Yongtaek Hong of Seoul National University have developed a nanostructure-aligned stretchable substrate that dramatically lowers the Poisson’s ratio. The work is published in the journal Advanced Materials.
The current microelectronics manufacturing method is expensive, slow and energy and resource intensive.
But a Northeastern University professor has patented a new process and printer that not only can manufacture advanced electronics and chips more efficiently and cheaply, it can make them at the nanoscale.
“I thought that there must be an easier way to do this, there must be a cheaper way to do this,” says Ahmed A. Busnaina, the William Lincoln Smith professor and a distinguished university professor at Northeastern University. “We started, basically, with very simple physical chemistry with a very simple approach.”
A platform developed nearly 20 years ago previously used to detect protein interactions with DNA and conduct accurate COVID-19 testing has been repurposed to create a highly sensitive water contamination detection tool.
The technology merges two exciting fields—synthetic biology and nanotechnology—to create a new platform for chemical monitoring. When tuned to detect different contaminants, the technology could detect the metals lead and cadmium at concentrations down to two and one parts per billion, respectively, in a matter of minutes.
The paper was published this week in the journal ACS Nano and represents research from multiple disciplines within Northwestern’s McCormick School of Engineering.
