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X-ray four-wave mixing captures elusive electron interactions inside atoms and molecules

Scientists at the X-ray free-electron laser SwissFEL have realized a long-pursued experimental goal in physics: to show how electrons dance together. The technique, known as X-ray four-wave mixing, opens a new way to see how energy and information flow within atoms and molecules. In the future, it could illuminate how quantum information is stored and lost, eventually aiding the design of more error-tolerant quantum devices. The findings are reported in Nature.

Much of the behavior of matter arises not from electrons acting alone, but from the ways they influence each other. From chemical systems to advanced materials, their interactions shape how molecules rearrange, how materials conduct or insulate and how energy flows.

In many quantum technologies —not least quantum computing—information is stored in delicate patterns of these interactions, known as coherences. When these coherences are lost, information disappears—a process known as decoherence. Learning how to understand and ultimately control such fleeting states is one of the major challenges facing quantum technologies today.

First breathing ‘lung-on-chip’ developed using genetically identical cells

Researchers at the Francis Crick Institute and AlveoliX have developed the first human lung-on-chip model using stem cells taken from only one person. These chips simulate breathing motions and lung disease in an individual, holding promise for testing treatments for infections like tuberculosis (TB) and delivering personalized medicine.

The research is published in the journal Science Advances.

Air sacs in the lungs called alveoli are the essential site of gas exchange and also an important barrier against inhaled viruses and bacteria that cause respiratory diseases like flu or TB.

Archaeology, Anthropology, and Interstellar Communication

Addressing a field that has been dominated by astronomers, physicists, engineers, and computer scientists, the contributors to this collection raise questions that may have been overlooked by physical scientists about the ease of establishing meaningful communication with an extraterrestrial intelligence. These scholars are grappling with some of the enormous challenges that will face humanity if an information-rich signal emanating from another world is detected. By drawing on issues at the core of contemporary archaeology and anthropology, we can be much better prepared for contact with an extraterrestrial civilization, should that day ever come.

NASA SP-2013–4413

Tiny tech, big AI power: What are 2-nanometer chips?

Taiwan’s world-leading microchip manufacturer TSMC says it has started mass producing next-generation “2-nanometer” chips.

AFP looks at what that means, and why it’s important:

What can they do? The computing power of chips has increased dramatically over the decades as makers cram them with more microscopic electronic components.

Soft, 3D transistors could host living cells for bioelectronics

New research from the WISE group (Wearable, Intelligent, Soft Electronics) at The University of Hong Kong (HKU-WISE) has addressed a long-standing bioelectronic challenge: the development of soft, 3D transistors.

This work introduces a new approach to semiconductor device design with transformative potential for bioelectronics. It is published in Science.

Led by Professor Shiming Zhang from the Department of Electrical and Electronic Engineering, Faculty of Engineering, the research team included senior researchers who joined HKU-WISE from the University of Cambridge and the University of Chicago, together with HKU Ph.D. students and undergraduate participants—an international, inclusive, and dynamic research community.

Neutral-atom arrays, a rapidly emerging quantum computing platform, get a boost from researchers

For quantum computers to outperform their classical counterparts, they need more quantum bits, or qubits. State-of-the-art quantum computers have around 1,000 qubits. Columbia physicists Sebastian Will and Nanfang Yu have their sights set much higher.

“We are laying critical groundwork to enable quantum computers with more than 100,000 qubits,” Will said.

In a paper published in Nature, Will, Yu, and their colleagues combine two powerful technologies— optical tweezers and metasurfaces—to dramatically scale the size of neutral-atom arrays.

Familial Hypercholesterolemia Screening in Childhood and Early Adulthood: A Cost-Effectiveness Study

Sequential childhood or early adulthood screening for familial hypercholesterolemia may lower lifetime CVD risk, but is unlikely to be cost-effective unless ongoing follow-up for elevated cholesterol is widely implemented.


This study uses a computer model to estimate the cost-effectiveness of sequential familial hypercholesterolemia screening at age 10 or 18 years using 3 low-density lipoprotein cholesterol (LDL-C) thresholds.

裂 The Virus That Rewrote Its Own Rulebook: What D1.1 Teaches Us About Living in an Evolving World

Bird Flu 2026

Researchers analyzed 17,500 genomes using Bayesian phylodynamics. Mapped origin, spread, and evolutionary timeline with precision.

The infrastructure failure: Of 1,722 D1.1 sequences, 9% have complete metadata (date + location).

We’re tracking a super-spreader blind.

#OpenScience #DataScience


“Avian Flu in North America: The D1.1 Evolutionary Leap” explores the emergence of a game-changing H5N1 virus variant that has fundamentally altered North America’s disease landscape since mid-2024. Through accessible explanation of cutting-edge genomic science, this episode reveals how the D1.1 genotype achieved unprecedented spread, infected all seven documented host categories including humans, and represents a major evolutionary shift. The podcast examines the massive computational effort behind tracking viral evolution, exposes critical gaps in our surveillance infrastructure, and confronts a paradigm-shifting reality: the Americas have become a primary engine of H5N1 evolution, reversing decades of global health assumptions.

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