How can improved methods for recycling tires help the environment? This is what a recent study published in Chem hopes to address as a team of researchers | Chemistry And Physics
Category: chemistry
Satyendra Nath Bose
Satyendra Nath Bose FRS, MP [ 1 ] (/ ˈ b oʊ s / ; [ 4 ] [ a ] 1 January 1894 – 4 February 1974) was an Indian theoretical physicist and mathematician. He is best known for his work on quantum mechanics in the early 1920s, in developing the foundation for Bose–Einstein statistics, and the theory of the Bose–Einstein condensate. A Fellow of the Royal Society, he was awarded India’s second highest civilian award, the Padma Vibhushan, in 1954 by the Government of India. [ 5 ] [ 6 ] [ 7 ]
The eponymous particles class described by Bose’s statistics, bosons, were named by Paul Dirac. [ 8 ] [ 9 ]
A polymath, he had a wide range of interests in varied fields, including physics, mathematics, chemistry, biology, mineralogy, philosophy, arts, literature, and music. He served on many research and development committees in India, after independence. [ 10 ] .
Exploring late accretion’s role in terrestrial planet evolution
Southwest Research Institute has collaborated with Yale University to summarize the scientific community’s notable progress in advancing the understanding of the formation and evolution of the inner rocky planets, the so-called terrestrial planets. Their paper focuses on late accretion’s role in the long-term evolution of terrestrial planets, including their distinct geophysical and chemical properties as well as their potential habitability.
The Review paper is published in the journal Nature.
Solar systems form when clouds of gas and dust begin to coalesce. Gravity pulls these elements together, forming a central star, like our sun, surrounded by a flattened disk of consolidating materials. Our terrestrial planets—Mercury, Venus, Earth and Mars—formed as smaller rocky objects accumulated, or accreted, into larger planetesimals and eventually protoplanets, when late impacts made critical contributions. Earth was probably the last terrestrial planet to form, reaching about 99% of its final mass within about 60–100 million years after the first solids began to consolidate.
A Fiery Mineral Found in an Icy Asteroid Baffles Scientists
A tiny grain from asteroid Ryugu has revealed djerfisherite, a mineral that normally forms in scorching, oxygen-poor settings—conditions Ryugu was never thought to experience.
The surprise find hints that the asteroid either endured unexpected heat spikes or captured exotic material transported across the early Solar System. Microscopy and chemical clues now challenge the idea that Ryugu is compositionally uniform and point to a far more chaotic mixing of planetary building blocks. Scientists are turning to isotopic “fingerprints” to trace the grain’s true origin and decode how primitive asteroids really formed.
Hayabusa2 brings ryugu samples & surprising mineral clues.
Highly Scalable, Wearable Surface‐Enhanced Raman Spectroscopy
The last two decades have witnessed a dramatic growth of wearable sensor technology, mainly represented by flexible, stretchable, on-skin electronic sensors that provide rich information of the wearer’s health conditions and surroundings. A recent breakthrough in the field is the development of wearable chemical sensors based on surface-enhanced Raman spectroscopy (SERS) that can detect molecular fingerprints universally, sensitively, and noninvasively. However, while their sensing properties are excellent, these sensors are not scalable for widespread use beyond small-scale human health monitoring due to their cumbersome fabrication process and limited multifunctional sensing capabilities. Here, a highly scalable, wearable SERS sensor is demonstrated based on an easy-to-fabricate, low-cost, ultrathin, flexible, stretchable, adhesive, and biointegratable gold nanomesh. It can be fabricated in any shape and worn on virtually any surface for label-free, large-scale, in situ sensing of diverse analytes from low to high concentrations (10–106 × 10−9 m). To show the practical utility of the wearable SERS sensor, the sensor is tested for the detection of sweat biomarkers, drugs of abuse, and microplastics. This wearable SERS sensor represents a significant step toward the generalizability and practicality of wearable sensing technology.
Beyond the crystal: Dynamic model captures loop flexibility in swine virus drug design
Porcine reproductive and respiratory syndrome virus (PRRSV) continues to devastate the global swine industry, yet the structural basis of how small molecules block its entry into host cells remains unclear. Researchers at the University of Tsukuba and Mahidol University developed a refined model of the PRRSV receptor domain CD163-SRCR5 using state-of-the-art computational approaches, offering new avenues for rational drug design.
While traditional drug discovery often relies on static crystal structures, many biologically important proteins, including the scavenger receptor CD163-SRCR5, contain flexible loop regions poorly captured by crystallography. These loops are critical for recognizing ligands and viral proteins, making them challenging yet attractive drug targets.
In their new study published in The Journal of Physical Chemistry Letters, the researchers used molecular dynamics (MD) simulations, ensemble docking, and fragment molecular orbital calculations to generate a dynamic, physiologically relevant structural model of the CD163-SRCR5 domain.
SGLT-2 Inhibitors and Serious Liver Events in Patients With Cirrhosis
This retrospective cohort study was conducted using data from TriNetX, a multi-institutional health research network. Using the TriNetX platform, we accessed deidentified electronic health records from over 212 million patients across 120 major health care organizations.9 The built-in analytic functions of TriNetX enable patient-level analyses while ensuring that only population-level data are reported.
This study was approved by WCG Clinical, which granted a waiver to TriNetX as a federated network and was deemed exempt from informed consent owing to the use of existing, non–human participant data that were deidentified per the US Health Insurance Portability and Accountability Act privacy rule. The study followed the Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) reporting guideline.
We included patients with cirrhosis (International Statistical Classification of Diseases and Related Health Problems, Tenth Revision [ICD-10] codes K74.6 and K74.69), who were taking furosemide (RxNorm [National Library of Medicine] code 4603) and spironolactone (RxNorm code 9997) between January 2013 and July 2021. For patients receiving an SGLT-2 inhibitor (Anatomical Therapeutic Chemical code A10BK), the index event was defined as the date on which they were concurrently prescribed spironolactone, furosemide, and an SGLT-2 inhibitor. For the control group, the index event was the date on which they were prescribed concurrent spironolactone and furosemide but not an SGLT-2 inhibitor. Each patient was followed up for 3 years from the index event, with follow-up ending on July 11, 2024.
Artificial photosynthesis system surpasses key efficiency benchmark for direct solar-to-hydrogen conversion
A research team affiliated with UNIST has introduced a cutting-edge modular artificial leaf that simultaneously meets high efficiency, long-term stability, and scalability requirements—marking a major step forward in green hydrogen production technology essential for achieving carbon neutrality.
Jointly led by Professors Jae Sung Lee, Sang Il Seok, and Ji-Wook Jang from the School of Energy and Chemical Engineering, this innovative system mimics natural leaves by producing hydrogen solely from sunlight and water, without requiring external power sources or emitting carbon dioxide during the process—a clean hydrogen production method. The study is published in Nature Communications.
Unlike conventional photovoltaic-electrochemical (PV-EC) systems, which generate electricity before producing hydrogen, this direct solar-to-chemical conversion approach reduces losses associated with electrical resistance and minimizes installation footprint. However, prior challenges related to low efficiency, durability, and scalability hindered commercial deployment.