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Apr 18, 2021

Ergothioneine: A ‘Longevity Vitamin’ With Potential Benefits For Age-Related Outcomes?

Posted by in categories: biotech/medical, life extension, neuroscience

Papers referenced in the video:

Dietary Thiols: A Potential Supporting Strategy against Oxidative Stress in Heart Failure and Muscular Damage during Sports Activity:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7765667/

Continue reading “Ergothioneine: A ‘Longevity Vitamin’ With Potential Benefits For Age-Related Outcomes?” »

Apr 15, 2021

Part-human, part-monkey embryos grown in lab dishes

Posted by in categories: bioengineering, biotech/medical, life extension

Scientists injected dozens of human stem cells into developing monkey embryos, and the resulting hybrids survived for up to 20 days in lab dishes.

These human-monkey embryos could someday serve as helpful models for human disease, embryonic development and aging, the study authors noted in a new report, published April 15 in the journal Cell. By zooming in on the interaction of human and animal cells in the embryos, scientists could also learn how to help human cells survive amongst animal cells, potentially advancing the effort to grow human organs in living animal models.

Apr 14, 2021

Bill Gates Backs the Waterless Toilet

Posted by in categories: life extension, solar power, sustainability

The waterless toilet was developed by Cranfield University.
The toilet was developed for use in countries that doesn’t have running water.
This toilet doesn’t smell which is a result of multiple actions that go on beneath the toilet once the lid is closed.
–A set of gears within the toilet are turned when the lid is closed, these gears rotate the basin where the fecal delight was deposited.
–The waste falls into a holding chamber where a swipe blade wipes the inside of the holding basin.
–The solids drop down to the bottom, and the liquid floats to the top.
–An archimedes screw carries the waste upwards where it gets rolled into pellets that drop into a combustor and are burned.
–The combustor on the toilet will be on all the time but will require an initial source of power to get it going. The team had an initial idea of attaching a hand crank or a bicycle to generate the power needed but recently scrapped that idea. A solar panel could be installed above the toilet but that wouldn’t be very cost effective. The team has other ideas they are still working through to solve this issue.
–The poop ash that is accumulated from the combustor needs to be removed once a week.
–The liquid floats through a set of pipes that are above the combustor.
–The liquid is heated and passed through a set of 4 membrane bundles that purifies the water.
–This purified water drips down to the bottom where it travels to and is stored in the front step of the toilet.
–This water while purified isn’t clean enough to drink but it can be used in the garden to grow plants as well as for cleaning.
–This waterless toilet needs to be serviced every 3 months, the 4 membranes need to be replaced to continue to purify the water.
–So now you have the full overview of this toilet what problems do you guys foresee with this invention?
–The only thing I’m going to say is that I’m sure the swipe blade will wipe most of the poop out of the holding basin, you know there’s gonna be some nasty skip marks in there.
In reality though places in the world where people have real struggles in life, a skip mark isn’t one of them.

Sources:
https://www.youtube.com/watch?v=jGPpXF7y9Rg.
http://www.sciencedirect.com/science/article/pii/S0196890416306628

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Apr 14, 2021

Donna Butts, Exec. Director, Generations United — Health, Aging, And Intergenerational Collaboration

Posted by in categories: innovation, life extension

Donna butts — executive director, generations united — focusing on the psycho-social aspects of healthy aging and wellness.


Donna Butts is the Executive Director of Generations United, an organization with a mission to improve the lives of children, youth, and older people through intergenerational collaboration, public policies, and programs for the enduring benefit of all, a position she has held since 1997. For more than 30 years, Ms. Butts has worked tirelessly to promote the well-being of children, youth and older adults through nonprofit organizations across the country and around the world. She began her career in her home state of Oregon as a youth worker with the YWCA, where she worked one-on-one with teens and saw the positive effects of intergenerational programs firsthand.

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Apr 14, 2021

Change Your Diet Change Your Life

Posted by in categories: biotech/medical, food, life extension

How seriously do you take your diet?

It is one of the foundations upon which everything else stands.

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Apr 13, 2021

AgeX Discussion of Paper on Protocadherins, Aging, and Regeneration

Posted by in categories: biotech/medical, life extension

Click on photo to start video.

Michael D. West talking about regeneration.


[Reuploaded from Vimeo: https://vimeo.com/522148118]

In this video, Dr. Michael West, CEO of AgeX Therapeutics, discusses the non-peer reviewed preprint article in bioRxiv on the potential role of the clustered protocadherin genes in regeneration, aging, and cancer, and the relevance of the discovery for iTR product development.

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Apr 12, 2021

Aubrey de Grey talks about putting aging under medical control (con S/T en Español)

Posted by in categories: biotech/medical, life extension

Aubrey de Grey’s talk during the South Summit that took place in Spain last October 2020. Aubrey explains why he thinks science and technology is close to bringing aging under complete medical control.

He also describes how along the process we will reach what he calls “Longevity Escape Velocity”. Once we reach it, we will be able to stay one step ahead of the curve of aging, and extend significantly, eventually indefinetely, human health and lifespan.

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Apr 12, 2021

Study reveals neural stem cells age rapidly

Posted by in categories: biotech/medical, engineering, life extension, neuroscience

In a new study published in Cell Stem Cell, a team led by USC Stem Cell scientist Michael Bonaguidi, Ph.D., demonstrates that neural stem cells—the stem cells of the nervous system—age rapidly.

“There is chronological aging, and there is , and they are not the same thing,” said Bonaguidi, an Assistant Professor of Stem Cell Biology and Regenerative Medicine, Gerontology and Biomedical Engineering at the Keck School of Medicine of USC. “We’re interested in the biological aging of neural stem cells, which are particularly vulnerable to the ravages of time. This has implications for the normal cognitive decline that most of us experience as we grow older, as well as for dementia, Alzheimer’s disease, epilepsy and .”

In the study, first author Albina Ibrayeva, a Ph.D. candidate in the Bonaguidi Lab in the Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research at USC, joined her colleagues in looking at the brains of young, middle-aged and .

Apr 11, 2021

‘Artificial Immortality’: Watch The First Trailer For Hot Docs Opener About AI & Biotech

Posted by in categories: biotech/medical, education, life extension, robotics/AI, singularity

The film features Nick Bostrom, author of Superintelligence; Japanese roboticist, Hiroshi Ishiguro; Douglas Rushkoff, author of Team Human; Ben Goertzel, founder of Singularity.net; and Deepak Chopra, who is creating his own A.I. mind twin.


EXCLUSIVE: Here’s the first trailer for Hot Docs opener Artificial Immortality by filmmaker Ann Shin.

The documentary explores the latest advancements in AI, robotics and biotech with visionaries who argue for a new age of post-biological life. It poses the questions: if you were able to create an immortal version of yourself, would you?; and will AI be the best, or the last thing we ever do as a species?

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Apr 11, 2021

Aging isn’t nice — Let’s bring world leaders to the quest of solving it

Posted by in categories: biotech/medical, life extension, neuroscience

Aging is maleable and can be intervened to slow down and even reverse it.
Several experiments in animal models have shown that certain gene therapies as well as interventions via partial cellular reprograming can significantly extend healthspan and lifespan in mice and other model organisms.

An article published on December 30, 2020 in Fortune magazine, reaches the following conclusions:
* Without treatments to slow or reverse aspects of biological aging, an aging population means we are in for a health care cost tsunami.
* The most exciting opportunity for such an improvement in health productivity is to understand and address the biology of aging.
* There is promising scientific research on reversing aspects of aging, some of which is not far from clinical application.
* While all this research represents thrilling progress, we invest far too little in research that could help us go further in understanding and treating aging.

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