A blood-test analysis developed at Stanford Medicine can determine the “biological ages” of 11 separate organ systems in individuals’ bodies and predict the health consequences.
Category: life extension
NASA Flips a Mars Orbiter Upside Down — And Discovers a Hidden World
NASA’s Mars Reconnaissance Orbiter (MRO) is a long-running spacecraft mission dedicated to studying the Red Planet from orbit. Launched in 2005 and managed by NASA’s Jet Propulsion Laboratory (JPL) in Southern California for the agency’s Science Mission Directorate, MRO is part of NASA’s broader Mars Exploration Program. It plays a key role in analyzing Mars’ surface, atmosphere, and subsurface using a suite of advanced instruments.
One of MRO’s standout tools is SHARAD (Shallow Radar), which probes beneath the Martian surface to detect features like ice and rock layers. Provided by the Italian Space Agency and operated by Sapienza University of Rome, SHARAD is a collaborative effort analyzed by a joint U.S.-Italian science team, with U.S. participation led by the Planetary Science Institute in Tucson, Arizona.
Lockheed Martin Space, based in Denver, built the orbiter and continues to support its operations, ensuring the spacecraft’s longevity and scientific productivity well into its second decade.
Cheap Daily Supplement Appears to Boost Brain Function in Older People
What’s good for your aging gut may also be good for your aging brain. The first study of its kind in twins found that taking daily protein and prebiotic supplements can improve scores on memory tests in people over the age of 60.
Published early last year, the findings are food for thought, especially as the same visual memory and learning test is used to detect early signs of Alzheimer’s disease.
The double-blinded trial involved two cheap plant fiber prebiotics that are available over the counter in numerous nations around the world.
Mitochondria Expert: This Supplement Reversed Vascular Aging by 20 Years
Discover how MitoQ reverses vascular aging by 15–20 years! Chief Scientific Officer Dr. Mitchell reveals research on mitochondrial health, showing 42% improvement in blood flow and superior results vs CoQ10 for longevity.
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Akkermansia https://pendulumtherapeutics.sjv.io/b… Daily https://pendulumtherapeutics.sjv.io/N… OmegaQuant 5% discount Code MODERN https://omegaquant.com/shop/ OneSkin 15% Discount: Code MODERN OS-01 Face https://oneskin.pxf.io/Z6Yg0K In this comprehensive interview, Dr. Mitchell, Chief Scientific Officer at MitoQ, breaks down the revolutionary science behind mitochondrial-targeted antioxidants and their impact on aging and disease prevention. *Key Topics Covered:* • How MitoQ delivers 90% bioavailability to mitochondria vs 10% for regular CoQ10 • Clinical study showing 42% improvement in flow-mediated dilation (vascular function) • Why mitochondrial dysfunction is the root cause of aging diseases • Exercise performance benefits: improved VO2 max, peak power, and recovery • Brain health and cognitive function improvements • Cardiovascular benefits: reduced oxidized LDL, improved artery flexibility • Immune system support and inflammation reduction • Diabetes prevention through improved glucose metabolism • Proper dosing protocols and supplement combinations *Research Highlights:* ✓ 25+ clinical studies and 800+ research papers ✓ Reverses vascular aging by 15–20 years according to leading researcher Doug Seals ✓ Professional cyclists and elite athletes using MitoQ for performance ✓ Ongoing trials for frailty, cognitive function, and neurovascular health ✓ 300+ independent researchers studying MitoQ applications Learn why targeting mitochondria may be the key to preventing age-related diseases and optimizing healthspan. Discover the science-backed approach to cellular energy and antioxidant protection that’s changing how we think about aging. ⏲️Chapters 0:00 The problem with mitochondria 3:34 How Mitochondria Dysfunction Occurs with Aging 5:43 Natural Protective Mechanisms and CoQ10 7:38 The Invention of MitoQ — Superior Mitochondrial Targeting 11:15 How MitoQ Differs from CoQ10 13:31 MitoQ vs CoQ10 — Research Comparisons 17:52 Cardiovascular Benefits and Flow-Mediated Dilation 23:32 Heart Muscle Function and Immune System Effects 28:16 Exercise Performance and V2 Max Improvements 32:04 Research Funding and Collaborative Programs 36:11 Diabetes Prevention and Glucose Metabolism 39:02 Brain Health and Cognitive Benefits 44:23 Dosing Protocol and Administration Guidelines 48:04 Supplement Combinations and Future Directions 🌐Links in this video MitoQ Home page https://www.mitoq.com/ Mitochondrial Collaborative Research Program https://www.mcrp.dev/ *************************************** Health claims Disclosure: Information provided on this video is not a substitute for direct, individual medical treatment or advice. Please consult with your doctor first. Products or services mentioned in this video are not a recommendation. Audio Copyright Disclaimer Please note that we have full authorization to the music that we used in our videos as they were created using the service WeVideo which provides the rights to the music. The rights are detailed in the terms of use that can be reviewed here https://www.wevideo.com/terms-of-use and any following inquiries should be addressed to [email protected]. ************************************************ #MitoQ #Mitochondria #Longevity.
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In this comprehensive interview, Dr. Mitchell, Chief Scientific Officer at MitoQ, breaks down the revolutionary science behind mitochondrial-targeted antioxidants and their impact on aging and disease prevention.
*Key Topics Covered:*
• How MitoQ delivers 90% bioavailability to mitochondria vs 10% for regular CoQ10
• Clinical study showing 42% improvement in flow-mediated dilation (vascular function)
• Why mitochondrial dysfunction is the root cause of aging diseases.
• Exercise performance benefits: improved VO2 max, peak power, and recovery.
• Brain health and cognitive function improvements.
• Cardiovascular benefits: reduced oxidized LDL, improved artery flexibility.
• Immune system support and inflammation reduction.
• Diabetes prevention through improved glucose metabolism.
• Proper dosing protocols and supplement combinations.
*Research Highlights:*
✓ 25+ clinical studies and 800+ research papers.
✓ Reverses vascular aging by 15–20 years according to leading researcher Doug Seals.
✓ Professional cyclists and elite athletes using MitoQ for performance.
✓ Ongoing trials for frailty, cognitive function, and neurovascular health.
✓ 300+ independent researchers studying MitoQ applications.
Learn why targeting mitochondria may be the key to preventing age-related diseases and optimizing healthspan. Discover the science-backed approach to cellular energy and antioxidant protection that’s changing how we think about aging.
When stem cells feel the squeeze, they start building bone
In a discovery that could reshape approaches to regenerative medicine and bone repair, researchers have found that human stem cells can be prompted to begin turning into bone cells simply by squeezing through narrow spaces.
The study suggests that the physical act of moving through tight, confining spaces, like those between tissues, can influence how stem cells develop. This could open new possibilities for engineering materials and therapies by guiding cell behavior using physical, rather than chemical, signals.
The research was led by Assistant Professor Andrew Holle from the Department of Biomedical Engineering in the College of Design and Engineering at the National University of Singapore (NUS), and the Mechanobiology Institute (MBI) at NUS, and was published on 8 May 2025 in the journal Advanced Science.
Can psychedelic mushrooms turn back the clock? Study suggests psilocybin preserves telomere length
A compound found in psychedelic mushrooms may have antiaging properties. Researchers at Baylor College of Medicine have found that psilocybin, the active compound in psychedelic mushrooms, may extend both cellular and organismal lifespans.
The findings, published in the journal npj Aging, show that psilocybin reduced multiple hallmarks of aging in cells while also improving survival in aged mice.
“There have been a number of clinical studies that have explored the therapeutic potential of psilocybin in psychiatric conditions such as depression and anxiety; however, few studies have evaluated its impacts outside the brain,” said Dr. Louise Hecker, associate professor of medicine— cardiovascular research at Baylor and senior author of the study.
Psilocybin treatment extends cellular lifespan and improves survival of aged mice
Psilocybin, the naturally occurring psychedelic compound produced by hallucinogenic mushrooms, has received attention due to considerable clinical evidence for its therapeutic potential to treat various psychiatric and neurodegenerative indications. However, the underlying molecular mechanisms remain enigmatic, and few studies have explored its systemic impacts. We provide the first experimental evidence that psilocin (the active metabolite of psilocybin) treatment extends cellular lifespan and psilocybin treatment promotes increased longevity in aged mice, suggesting that psilocybin may be a potent geroprotective agent.
Kato, K., Kleinhenz, J.M., Shin, YJ. et al. Psilocybin treatment extends cellular lifespan and improves survival of aged mice. npj Aging 11, 55 (2025). https://doi.org/10.1038/s41514-025-00244-x.
Functional Features of Senescent Cells and Implications for Therapy
Cellular senescence is a key mechanism of aging. Senescent cells negatively affect the function of tissues and organs, significantly contributimg to the aging of the organism. Functional and structural characteristics of senescent cells, such as genomic changes and cell cycle arrest, lysosome and mitochondrial dysfunction, and production of SASP factors, are promising therapeutic targets in the context of healthy longevity. The present review was designed to characterize the features of senescent cells in order to discuss current methods and problems of geroprotective therapy and perspective factors for the development of new strategies of anti-aging treatment. Publications were searched based on the analysis of articles containing the keywords “senescent cells, aging, senolytic therapy, SASP, mitochondrial dysfunction” in the PubMed and Scopus databases up to March 2025.
