Lifeboat Foundation

The story illuminates the way that many scientific discoveries become life-changing innovations: with decades of dead ends, rejections and battles over potential profits, but also generosity, curiosity and dogged persistence against scepticism and doubt. “It’s a long series of steps,” says Paul Krieg, a developmental biologist at the University of Arizona in Tucson, who made his own contribution in the mid-1980s, “and you never know what’s going to be useful”.

Hundreds of scientists had worked on mRNA vaccines for decades before the coronavirus pandemic brought a breakthrough.

Simple creation of a super multi-element catalyst homogeneously containing 14 elements.

A research group in Japan has successfully developed a “nanoporous super multi-element catalyst”^[1] that contains 14 elements^[2] which are mixed uniformly at the atomic level and used as a catalyst. A high-entropy alloy.

A mixture of two metallic elements typically used to give greater strength or higher resistance to corrosion.

Continue reading “Realization of Omnipotent Catalysts Expected After Breakthrough Creation of Super Multi-Element Catalyst” »

That successful demonstration paves the way for practical, commercial, carbon-free power.

Circa 2014

Scientists researching nuclear energy have made a breakthrough in nuclear fusion with an experiment that generated more fuel than was put in.

Continue reading “Scientists Make Thermonuclear Fusion Breakthrough that Has No Real-World Application Yet” »

Tesla’s insane laser windshield wiper patent has been officially granted by the United States Patent Office this week. Filed in May 2,019 the U.S. Patent Office granted the application, giving Tesla an exclusive right for the invention.

Tesla has played around with several ideas for windshield wipers in the past. In fact, in February, the company had a patent approved for a new wiper design for the Roadster, which would utilize an electromagnetic linear actuator to rid the windshield of moisture. It would essentially move from one side of the windshield to the other with one wiper in one motion.

Tesla Roadster’s revolutionary wiper design secures U.S. Patent approval

Innovative coronavirus disease2019(COVID-19) vaccines, with elevated global manufacturing capacity, enhanced safety and efficacy, simplified dosing regimens, and distribution that is less cold chain-dependent, are still global imperatives for tackling the ongoing pandemic. A previous phase I trial indicated that the recombinant COVID-19 vaccine (V-01), which contains a fusion protein (IFN-PADRE-RBD-Fc dimer) as its antigen, is safe and well tolerated, capable of inducing rapid and robust immune responses, and warranted further testing in additional clinical trials. Herein, we aimed to assess the immunogenicity and safety of V-01, providing rationales of appropriate dose regimen for further efficacy study.

Methods:

A randomized, double-blind, placebo-controlled phase II clinical trial was initiated at the Gaozhou Municipal Centre for Disease Control and Prevention (Guangdong, China) in March 2021. Both younger (n = 440; 18–59 years of age) and older (n = 440; ≥60 years of age) adult participants in this trial were sequentially recruited into two distinct groups: two-dose regimen group in which participants were randomized either to follow a 10 or 25 μg of V-01 or placebo given intramuscularly 21 days apart (allocation ratio, 3:3:1, n = 120 120, 40 for each regimen, respectively), or one-dose regimen groups in which participants were randomized either to receive a single injection of 50 μg of V-01 or placebo (allocation ratio, 3:1, n = 120 40, respectively). The primary immunogenicity endpoints were the geometric mean titers of neutralizing antibodies against live severe acute respiratory syndrome coronavirus 2 and specific binding antibodies to the receptor binding domain (RBD).

Continue reading “Immunogenicity and safety of a recombinant fusion protein… : Chinese Medical Journal” »

Google shares its latest breakthroughs in the area of using artificial intelligence to upscale low-res photos, and the results are amazing.

A new coronavirus variant, C.1.2, has been detected in South Africa and a number of other countries, with concerns that the variant could be more infectious and evade vaccines, according to a new preprint study by South Africa’s National Institute for Communicable Diseases and the KwaZulu-Natal Research Innovation and Sequencing Platform. The study is awaiting peer review.

The C.1.2 variant first detected in South Africa is more mutated compared to the original virus than any other known variant.

Continue reading “New COVID variant detected in South Africa, most mutated variant so far” »