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Unfinished business: ending the HIV epidemic

SINCE the 1980s, researchers have worked tirelessly to develop effective treatments that can suppress the HIV virus to undetectable levels. As a result, by taking a single daily dose of an antiretroviral (ARV) medicine, people with HIV can now expect to live long and healthy lives – as well as prevent transmission to others.

The impact has been dramatic, with annual global AIDS-related deaths having fallen from 2.1 million at the peak in 2004 to 630,000 in 2024. The number of new acquisitions has plummeted too: an estimated 1.3 million people acquired the virus in 2024, marking a 60 per cent decline since the peak in 1995.

“We’re at a pivotal moment in the quest to end the HIV epidemic,” says Jean van Wyk, chief medical officer at ViiV Healthcare. This quest is to meet the UN’s 2030 goals that ViiV has been involved with since the 1980s as the pioneers of the first ARV medicine.

Video Conferencing, Web Conferencing, Webinars, Screen Sharing

Zoom is the leader in modern enterprise video communications, with an easy, reliable cloud platform for video and audio conferencing, chat, and webinars across mobile, desktop, and room systems. Zoom Rooms is the original software-based conference room solution used around the world in board, conference, huddle, and training rooms, as well as executive offices and classrooms. Founded in 2011, Zoom helps businesses and organizations bring their teams together in a frictionless environment to get more done. Zoom is a publicly traded company headquartered in San Jose, CA.

These Billionaires Plan To Bring Self-Driving Tech To Everything That Moves

Applied Intuition’s cofounders are building software that can drive everything from planes to tanks to automobiles. But to expand beyond its $800 million business selling tech for cars, they will have to take on Tesla, Google, Nvidia and a host of other startups jostling for pole position in the autonomy race.

What Growing Up On Mars Would Do to the Human Body

An enjoyable article exploring the science of reproduction in space. I appreciate the genuine curiosity and hopeful outlook here!

The annual SXSW conference in Austin, Texas, can be a bit overwhelming. What started as a fairly modest four-day music festival in 1987, drawing some 700 attendees, has become a ten-day extravaganza of panel presentations featuring celebrities and business leaders, film screenings, technology showcases, and—yes—music. These days hundreds of thousands of people converge on downtown Austin for “South By,” as it’s called by those in the know. When I was a graduate student at the University of Texas in the early 2000s, I always avoided the festival and its inevitable crowds, which was relatively easy to do since it tended to be held the same week as the university’s Spring Break.

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But when I received an invitation in 2023 to attend a SXSW panel presentation with the title “Sex in Space: Sex and Reproduction Beyond Earth,” I knew I had to go. After all, any plans to create a permanent settlement on Mars or elsewhere in space wouldn’t last long if we can’t have kids there.

PayPal discloses data breach that exposed user info for 6 months

PayPal is notifying customers of a data breach after a software error in a loan application exposed their sensitive personal information, including Social Security numbers, for nearly 6 months last year.

The incident affected the PayPal Working Capital (PPWC) loan app, which provides small businesses with quick access to financing.

PayPal discovered the breach on December 12, 2025, and determined that customers’ names, email addresses, phone numbers, business addresses, Social Security numbers, and dates of birth had been exposed since July 1, 2025.

Washington Hotel in Japan discloses ransomware infection incident

The Washington Hotel brand in Japan has announced that that its servers were compromised in a ransomware attack, exposing various business data.

The hospitality group has established an internal task force and engaged external cybersecurity experts to assess the impact of the intrusion, determine whether customer data was compromised, and coordinate recovery efforts.

Washington Hotel, a brand operating under Fujita Kanko Inc. (WHG Hotels), is a business-focused hospitality chain with 30 locations across Japan. WHG has 11,000 rooms over its properties and has nearly 5 million guests every year.

Q-Day: Catastrophic For Businesses Ignoring Quantum-Resistant Encryption

#Quantum #CyberSecurity

Quantum computing is not merely a frontier of innovation; it is a countdown. Q-Day is the pivotal moment when scalable quantum computers undermine the cryptographic underpinnings of our digital realm. It is approaching more rapidly than many comprehend.

For corporations and governmental entities reliant on outdated encryption methods, Q-Day will not herald a smooth transition; it may signify a digital catastrophe.

Comprehending Q-Day: The Quantum Reckoning

Q-Day arrives when quantum machines using Shor’s algorithm can dismantle public-key encryption within minutes—a task that classical supercomputers would require billions of years to accomplish.

Malicious Chrome Extensions Caught Stealing Business Data, Emails, and Browsing History

Cybersecurity researchers have discovered a malicious Google Chrome extension that’s designed to steal data associated with Meta Business Suite and Facebook Business Manager.

The extension, named CL Suite by @CLMasters (ID: jkphinfhmfkckkcnifhjiplhfoiefffl), is marketed as a way to scrape Meta Business Suite data, remove verification pop-ups, and generate two-factor authentication (2FA) codes. The extension has 33 users as of writing. It was first uploaded to the Chrome Web Store on March 1, 2025.

However, the browser add-on also exfiltrates TOTP codes for Facebook and Meta Business accounts, Business Manager contact lists, and analytics data to infrastructure controlled by the threat actor, Socket said.

How SpaceX and XAI Will Build Moonbase Alpha and Mass Drivers

SpaceX, in collaboration with xAI, plans to build a lunar base called Moonbase Alpha using advanced technologies such as mass drivers, solar power, and Starship, aiming to make human activity on the moon visible, affordable, and sustainable ##

## Questions to inspire discussion.

Launch Infrastructure Economics.

🚀 Q: What launch costs could SpaceX’s moon infrastructure achieve? A: Mature SpaceX moon operations could reduce costs to $10/kg to orbit and $50/kg to moon surface, enabling $5,000 moon trips for people under 100kg (comparable to expensive cruise pricing), as mentioned by Elon Musk.

⚡ Q: How could lunar mass drivers scale satellite deployment? A: Lunar mass drivers using magnetic rails at 5,600 mph could launch 10 billion tons of satellites annually with 2 terawatts of power, based on 2023 San Jose State study updating 1960s-70s mass driver literature.

Starship Capabilities.

Continue reading “How SpaceX and XAI Will Build Moonbase Alpha and Mass Drivers” | >

Claude Opus 4.6 vs GPT 5.3 Codex: Which is better for programming? | Peter Steinberger

Claude Opus 4.6 and GPT 5.3 Codex, two AI models, have different strengths and interaction styles, highlighting the trade-offs between elegance, reliability, and efficiency in their performance ##

## Questions to inspire discussion.

Model Selection Strategy.

🎯 Q: Which AI model should I choose for different programming tasks?

A: Use Opus for interactive roleplay and quick command following with trial-and-error workflows, while Codex excels at delivering elegant solutions when given proper context and reads more code by default.

🔄 Q: How long does it take to effectively switch between AI models?

Continue reading “Claude Opus 4.6 vs GPT 5.3 Codex: Which is better for programming? | Peter Steinberger” | >
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