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Alibaba’s Qwen 3

QWEN 3.5 running on iPhone Pro in airplane mode. Full large language model running onan edge device with no network connectivity.


5 is now running fully on device on an iPhone 17 Pro, and that’s a big deal.

Despite its compact size, Qwen 3.5 reportedly outperforms models up to four times larger. It shows strong multimodal capability, meaning it can interpret and reason over images as well as text. It also includes a reasoning toggle, letting users switch between faster responses and deeper step by step thinking depending on the task.

The demo uses a 2B parameter model quantized to 6 bit precision, optimized with MLX for Apple Silicon. That combination allows advanced AI to run locally, without relying on cloud servers.

If this scales, it signals a shift toward powerful, private, on device AI that doesn’t need a data center to compete.

Using tiny ripples at skin level to monitor for possible health problems below

Caltech scientists have developed a method that detects tiny, imperceptible movements at the surface of objects to reveal details about what lies beneath. By analyzing the physics of waves traveling across the surface of an object—whether that be a manufactured product or the human body—the new technique can determine both the stiffness and thickness of the underlying material or tissue. This lays the groundwork for the project’s ultimate goal of enabling inexpensive, at-home health monitoring using little more than a smartphone camera.

“There is information scattered all around us in plain sight that we just haven’t learned to tap into. Our work is trying to leverage that information to recover material properties from inside objects by studying tiny movements on the surface,” says Katie L. Bouman, professor of computing and mathematical sciences, electrical engineering, and astronomy at Caltech and both a Rosenberg Scholar and a Heritage Medical Research Institute (HMRI) Investigator.

Bouman and her colleagues from Caltech presented the technique, called visual surface wave elastography, and its medical applications in a paper presented at the International Conference on Computer Vision in Honolulu last fall. The lead authors are Alexander C. Ogren, Ph.D., and Berthy T. Feng, Ph.D., who completed the work while at Caltech.

Abstract: Challenging the dogma…

Here, Adrian Vella & team show hepatic resistance to glucagon’s effects on amino acid catabolism is not a significant factor in postprandial metabolism, regardless of obesity or hepatic steatosis: type2diabetes MASH Glucagon.


Address correspondence to: Adrian Vella, Endocrine Research Unit, Mayo Clinic College of Medicine, 200 First St. SW, 5–194 Joseph, Rochester, Minnesota 55,905, USA. Phone: 507.255.6515; Email: [email protected].

Find articles by Christie, H. in: | Google Scholar |

1Division of Endocrinology, Diabetes, Metabolism and Nutrition, Mayo Clinic, Rochester, Minnesota, USA.

Abstract: This study is directly relevant to the clinical care of patients with the most common malignant tumor of the peripheral nervous system

While providing fundamental biological insight👇

Harish N. Vasudevan & team reveal transcriptional, functional genetic, and cellular mechanisms of interferon signaling that underlie radiotherapy response in people with MPNST.


Address correspondence to: Harish N. Vasudevan, Helen Diller Cancer Research Building, 1,450 3rd Street, Mail Box 520, San Francisco, California 94,158, USA. Phone: 415.502.4107; Email: [email protected].

Encryption: A Key Guardian of Our Digital Future

By Chuck Brooks and Bill Bowers.


Every time you send a text, pay for groceries with your phone, or use your health site, you are relying on encryption. It’s an invisible shield that protects your data from prying eyes. Encryption is more than just a technological protection; it is the basis for digital trust.

Encryption is more than just safeguarding data; it is also about protecting people. It helps ensure privacy by protecting persons from spying and exploitation. And it is widely adopted to help ensure digital transaction security. For National Security it serves to protect key infrastructure and government communications. And it has a human rights function by providing citizens with peace of mind by ensuring the safety of their personal information. In places where surveillance is widespread, encryption can even defend free expression and opposition. It is a human right in this digital age.

In my book Inside Cyber: How AI, 5G, IoT, and Quantum Computing Will Transform Privacy and Security, I referred to encryption as the “linchpin of privacy and commerce in a connected society.” Without it, the digital economy would crumble under the strain of criminality, fraud, and spying.

Google Confirms CVE-2026–21385 in Qualcomm Android Component Exploited

There are currently no details on how the vulnerability is being exploited in the wild. However, Google acknowledged in its monthly Android security bulletin that “there are indications that CVE-2026–21385 may be under limited, targeted exploitation.”

Google’s March 2026 update contains patches for a total of 129 vulnerabilities, including a critical flaw in the System component (CVE-2026–0006) that could lead to remote code execution without requiring any additional privileges or user interaction. In contrast, Google addressed one Android vulnerability in January 2026 and none last month.

Also patched by Google are multiple critical-rated bugs: a privilege escalation bug in Framework (CVE-2026–0047), a denial-of-service (DoS) in System (CVE-2025–48631), and seven privilege escalation flaws in Kernel components (CVE-2024–43859, CVE-2026–0037, CVE-2026–0038, CVE-2026–0027, CVE-2026–0028, CVE-2026–0030, and CVE-2026–0031).

Abstract: This study challenges the long-standing notion of fibroblasts as passive bystanders in atopic dermatitis

Richard L. Gallo & team discover dermal fibroblasts respond to IL4 and IL13, producing Ccr3-binding chemokines, and driving T cell recruitment in atopic dermatitis:

The figure shows reduction of T cells (red) in an CCR3 antagonist-treated mouse model of atopic dermatitis.


Address correspondence to: Richard L. Gallo, Department of Dermatology, MC0869, UCSD, 9,500 Gilman Dr., La Jolla, California, 92,093, USA. Phone: 858.822.4608; Email: [email protected].

Find articles by Numata, T. in: | Google Scholar |

Department of dermatology, UCSD, la jolla, california, USA.

Abstract: The changing landscape of urothelial carcinoma: on the edge of paradigm shift

In this Review Joshua J. Meeks discusses advancements in biomarkers and novel therapeutics that are likely to dramatically improve survival of patients with Bladder Cancer.


1Departments of Urology and.

2Biochemistry and Molecular Genetics, Northwestern University, Feinberg School of Medicine, Chicago, Illinois, USA.

3Jesse Brown VA Medical Center, Department of Veterans Affairs, Chicago, Illinois, USA.

Address correspondence to: Joshua J. Meeks, Department of Urology, Biochemistry and Molecular Genetics, Northwestern University, Feinberg School of Medicine, Chicago, Illinois, USA. Phone: 312.695.8146; Email: [email protected].

Simulations show a path to ‘ideal glass’ with crystal-like entropy

The types of glass that we encounter in everyday life, such as window glass or smartphone screens, are disordered solids. This means that they consist of particles locked in place, like those in solids, but arranged randomly, similarly to how they would be in a liquid.

Almost a century ago, Walter Kauzmann, who was a chemistry professor at Princeton University at the time, was confronted with the possible existence of a so-called ideal glass, an amorphous system with the entropy of a crystal. This is a glass in which particles are still arranged randomly, but the particles fill space so efficiently that there is only one possible arrangement, as opposed to the many disordered arrangements of conventional glass.

Kauzmann’s theoretical proposals inspired numerous other physicists to explore the idea of this perfectly equilibrated glass. Previous studies suggested that this elusive state could not be reached using conventional cooling processes.

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