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Archive for the ‘life extension’ category: Page 349

Oct 31, 2019

In the long run, mutation is the key to evolution, but in the short run, it’s not exactly your health’s best friend

Posted by in categories: evolution, life extension

Here’s how genomic instability messes with your body and contributes to aging.

Oct 31, 2019

Delay ageing

Posted by in category: life extension

Want to stay young for long? If so, start exercising four to five times a week as it may help keep your heart stay healthy and slow down ageing, according to researchers.

Research showed that different sizes of arteries are affected differently by varying amounts of exercise.

While exercising for about two to three days a week for about 30 minutes may be sufficient to minimise stiffening of middle-sized arteries, exercising for about four to five days a week is required to keep the larger central arteries youthful.

Oct 30, 2019

CNIO researchers obtain the first mice born with hyper-long telomeres and show that it is possible to extend life without any genetic modification

Posted by in categories: biotech/medical, genetics, life extension

A chance finding ten years ago led to the creation by researchers of the Spanish National Cancer Research Centre (CNIO) of the first mice born with much longer telomeres than normal in their species. Given the relationship between telomeres and ageing – telomeres shorten throughout life, so older organisms have shorter telomeres -, scientists launched a study generating mice in which 100% of their cells had hyper-long telomeres. The findings are published in Nature Communications and show only positive consequences: the animals with hyper-long live longer in better health, free from cancer and obesity. The most relevant thing for the authors is the fact that longevity has been significantly increased for the first time ever without any genetic modification.

“This finding supports the idea that, when it comes to determining longevity, genes are not the only thing to consider”, indicates Maria Blasco, Head of the CNIO Telomeres and Telomerase Group and intellectual author of the paper. “There is margin for extending life without altering the genes”.

Telomeres form the end of chromosomes, in the nucleus of each cell in the body. Their function is to protect the integrity of the genetic information in DNA. Whenever the cells divide the telomeres, they are shortened a little, so one of the main characteristics of ageing is the accumulation of short telomeres in cells. “Telomere shortening is considered to be one of the primary causes of ageing, given that short telomeres cause ageing of the organism and reduce longevity”, as the paper published in Nature Communications explains.

Oct 30, 2019

Immortality’s a Red Herring; We Want Indefinite Life Extension

Posted by in categories: biotech/medical, life extension

A few years ago, popular YouTuber Life Noggin published a video titled “WHY DO WE DIE?” In this video, he briefly goes into the science behind the gradual cellular degradation of the biological substrate, which causes all known side-effects associated with aging. At the end of the video, however, he revealed that he’d much rather “live forever” than die.

As a result, his subscribers, which is nearly at 2.9 million, took to the comments section to overwhelmingly declare similar hopes. Not everyone was convinced, however.


As we continue searching for the cure to aging, we’ll need to better inform the public that we’ve no intention of dictating how long they’re to live and when they’re to die.

Continue reading “Immortality’s a Red Herring; We Want Indefinite Life Extension” »

Oct 29, 2019

Kevin Strange at Ending Age-Related Diseases 2019

Posted by in categories: biotech/medical, life extension

We’re continuing to release talks from Ending Age-Related Diseases 2019, our highly successful two-day conference that featured talks from leading researchers and investors, bringing them together to discuss the future of aging and rejuvenation biotechnology.

Kevin Strange discussed his company, Novo Biosciences, and how it is developing small molecules that restore the body’s ability to regenerate. He went into detail about how humans begin life with this ability but lose it as they age. He discussed MSI-1436, which is a prospective drug for reversing ischemic heart injury and making life easier for survivors of heart attack as well as reversing skeletal muscle degeneration.

Oct 29, 2019

Advances in anti-ageing research: how chemistry could hold the key to better health

Posted by in categories: chemistry, life extension

Has the chemistry of ageing come of age?

Oct 29, 2019

Curing biological Aging & Gene Therapy with Liz Parrish and Dr. Nick Delgado at RaadFest, Las Vegas

Posted by in categories: biotech/medical, genetics, life extension

Dr. Nick interviews Liz Parrish, the Founder, and CEO of BioViva Sciences USA Inc at RaadFest in Las Vegas. Nick Delgado, ABAAHP is one of the leading experts in the field of bio-identical hormones, herbs, nutrition, exercise, partner intimacy, mindful self-motivation. Our goal is to help you restore your cellular health to radically improve the quality of life and world health.
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Liz Parrish is the Founder and CEO of BioViva Sciences USA Inc. BioViva is committed to extending healthy lifespans using gene therapy. Liz is known as “the woman who wants to genetically engineer you,” she is a humanitarian, entrepreneur and innovator and a leading voice for genetic cures.
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Continue reading “Curing biological Aging & Gene Therapy with Liz Parrish and Dr. Nick Delgado at RaadFest, Las Vegas” »

Oct 29, 2019

SENS MitoMouse Q&A Webinar Video

Posted by in categories: biotech/medical, life extension

On Friday, October 25, we hosted a Q&A webinar with the team behind MitoMouse, the second MitoSENS program that we are funding. In this webinar, Drs. Aubrey de Grey, Amutha Boominathan, and Matthew “Oki” O’Connor answered viewer questions about the nature of their research and the SENS approach to age-related disease.

There are only a few days left to donate! If you haven’t already, help SENS Research Foundation fund the final stretch goal of this critical research at https://lifespan.io/mitomouse and help bring about the end of mitochondrial dysfunction more quickly.

Oct 28, 2019

Alert system for failing nuclear plant pipes uses thin films and sound vibrations

Posted by in categories: 3D printing, food, life extension, nanotechnology

A failing pipe can be tough to spot. It may cause a puddle, produce another sign of damage, or simply burst before detection. A flooded kitchen or laundry room is messy and inconvenient, but the stakes are much, much higher in nuclear power plants—which on average contain many miles of pipeline.

As concern about aging plants escalates, Vanderbilt engineers are working on an early warning system. They are using on the inside of the and 3D-printed polymer devices infused with nanoparticles as sensors to signal the changes on the outside of the pipe. And, they hope, sound.

A huge challenge is to detect the changes in the polymer film occurring inside the pipe. To create a useful and proactive technique, the team wants to use sound, or vibrometry, to identify these internal changes from outside the pipe.

Oct 27, 2019

What are the ethical consequences of immortality technology?

Posted by in categories: biotech/medical, finance, life extension

Immortality has gone secular. Unhooked from the realm of gods and angels, it’s now the subject of serious investment – both intellectual and financial – by philosophers, scientists and the Silicon Valley set. Several hundred people have already chosen to be ‘cryopreserved’ in preference to simply dying, as they wait for science to catch up and give them a second shot at life. But if we treat death as a problem, what are the ethical implications of the highly speculative ‘solutions’ being mooted?

Of course, we don’t currently have the means of achieving human immortality, nor is it clear that we ever will. But two hypothetical options have so far attracted the most interest and attention: rejuvenation technology, and mind uploading.

Like a futuristic fountain of youth, rejuvenation promises to remove and reverse the damage of ageing at the cellular level. Gerontologists such as Aubrey de Grey argue that growing old is a disease that we can circumvent by having our cells replaced or repaired at regular intervals. Practically speaking, this might mean that every few years, you would visit a rejuvenation clinic. Doctors would not only remove infected, cancerous or otherwise unhealthy cells, but also induce healthy ones to regenerate more effectively and remove accumulated waste products. This deep makeover would ‘turn back the clock’ on your body, leaving you physiologically younger than your actual age. You would, however, remain just as vulnerable to death from acute trauma – that is, from injury and poisoning, whether accidental or not – as you were before.