Archive for the ‘life extension’ category: Page 352
Sep 24, 2019
Dr. Fernando Llorca Castro — Costa Rica’s Ambassador to the United States — ideaXme Show — Ira Pator
Posted by Ira S. Pastor in categories: aging, biotech/medical, geopolitics, governance, government, health, innovation, life extension, science, transhumanism
Sep 24, 2019
Reason at Ending Age-Related Diseases 2019
Posted by Steve Hill in categories: biotech/medical, life extension
We’re continuing to release talks from Ending Age-Related Diseases 2019, our highly successful two-day conference that featured talks from leading researchers and investors, bringing them together to discuss the future of aging and rejuvenation biotechnology.
In his talk, Reason of Repair Biotechnologies addressed the reasons why rejuvenation biotechnology is not proceeding as fast as it could be and discussed the ways in which his company is helping to expedite its development and release.
Sep 21, 2019
I Dismember Mama — Saul Kent, promoter of cryogenic immortality Part 1
Posted by Paul Battista in categories: electronics, life extension
From the Errol Morris tv series First Person.
This episode features the eccentric Saul Kent, promoter of cryogenic immortality.
Sep 21, 2019
Cyborgs and immortality: into the research of Dr. Huberman
Posted by Paul Battista in categories: cyborgs, life extension, transhumanism
Who doesn’t want to live forever?
Every society has its own set of myths about finding eternal life: the Fountain of Youth for the Spaniards and Shangri La for the Chinese, for example. For the transhumanists, this myth may become a reality.
Dr. Jennifer Huberman is a cultural anthropology professor at UMKC whose recent research has focused on this emerging high-tech society. Initially, Huberman did not set out to study the transhumanists.
Sep 20, 2019
Greg Fahy at Ending Age-Related Diseases 2019
Posted by Steve Hill in categories: biotech/medical, genetics, life extension
We’re continuing to release talks from Ending Age-Related Diseases 2019, our highly successful two-day conference that featured talks from leading researchers and investors, bringing them together to discuss the future of aging and rejuvenation biotechnology.
Dr. Greg Fahy of Intervene Immune gave a presentation about his company’s Phase 1 human trials in which the thymus, a critical organ of the immune system, was regenerated through a combination of existing drugs, restoring immune function and causing epigenetic biomarkers to show rejuvenation.
Sep 20, 2019
AgeX Therapeutics Publishes Theoretical Basis of Human Cell Age-Reversal in the Journal Regenerative Medicine
Posted by Montie Adkins in categories: biotech/medical, business, life extension
A unified theory of ageing, there is a vid and a paper linked within.
ALAMEDA, Calif.—( BUSINESS WIRE )—AgeX Therapeutics, Inc. (“AgeX”; NYSE American: AGE), a biotechnology company focused on therapeutics for human aging and regeneration, announced today that founder and CEO Michael D. West, Ph.D., and colleagues have authored a paper in the peer-reviewed scientific journal Regenerative Medicine on the theoretical foundation of the Company’s induced Tissue Regeneration (iTRTM) technology. The paper presents the work of the company’s scientists in describing a unified theory of aging and regeneration that could pave the way for the development of new therapies for a variety of age-related degenerative diseases and conditions.
“The longevity sector is advancing at an accelerating pace, but for the most part, without a consensus on the fundamental root causes of aging,” commented Dr. West. “We believe that it is now possible to collate the diverse observations about aging into a unified model. In the paper titled, ‘Toward a Unified Theory of Aging and Regeneration’ we outline such a theory that underlies the technological underpinnings of the company’s induced tissue regeneration (iTR) program.”
Sep 19, 2019
Rise of the new age billionaires; rise of the investments in longevity!
Posted by Paul Battista in category: life extension
If there’s anything that’s captivated mankind’s imagination more than new ways to kill one another, it’s how to beat the grim reaper. Just kidding, how to kill people still generates the most funding of all, but this article isn’t about that, it’s about immortality and the new age billionaires who are funding it.
Sep 19, 2019
The end of aging: Are you ready to live to 150?
Posted by Genevieve Klien in categories: biotech/medical, genetics, life extension
Meet the Harvard genetics genius who says we can stop growing old today – even without futuristic drugs.
Sep 19, 2019
The design, construction and characterization of new nanovibrational bioreactors for osteogenesis
Posted by Gerard Bain in categories: bioengineering, biotech/medical, computing, life extension, nanotechnology
In regenerative medicine, scientists aim to significantly advance techniques that can control stem cell lineage commitment. For example, mechanical stimulation of mesenchymal stem cells (MSCs) at the nanoscale can activate mechanotransduction pathways to stimulate osteogenesis (bone development) in 2-D and 3D culture. Such work can revolutionize bone graft procedures by creating graft material from autologous or allogenic sources of MSCs without chemically inducing the phenomenon. Due to increasing biomedical interest in such mechanical stimulation of cells for clinical use, both researchers and clinicians require a scalable bioreactor system to provide consistently reproducible results. In a new study now published on Scientific Reports, Paul Campsie and a team of multidisciplinary researchers at the departments of biomedical engineering, computing, physics, and molecular, cell and systems biology engineered a new bioreactor system to meet the existing requirements.
The new instrument contained a vibration plate for bioreactions, calibrated and optimized for nanometer vibrations at 1 kHz, a power supply unit to generate a 30 nm vibration amplitude and custom six-well cultureware for cell growth. The cultureware contained magnetic inserts to attach to the bioreactor’s magnetic vibration plate. They assessed osteogenic protein expression to confirm the differentiation of MSCs after initial biological experiments within the system. Campsie et al. conducted atomic force microscopy (AFM) of the 3D gel constructs to verify that strain hardening of the gel did not occur during vibrational stimulation. The results confirmed cell differentiation to be the result of nano-vibrational stimulations provided by the bioreactor alone.
The increasing incidence of skeletal injuries due to age-related conditions such as osteoporosis and osteoarthritis is a metric of the depleting quality of human life. The development of treatments for increased bone density or fracture healing are prime targets for the regenerative potential of mesenchymal stem cells (MSCs). Researchers have demonstrated controlled osteogenesis (development of bones) of MSCs via mechanical stimulation using several methods, including passive and active strategies. Passive methods typically alter the substrate topography to influence the cell adhesion profile, while active methods include exposure to varied forces from external sources.
