The ancient evolution of fish mouths could help solve a modern source of plastic pollution.
Inspired by these natural filtration systems, scientists in Germany have invented a way to remove 99 percent of plastic particles from water. It’s based on how some fish filter-feed to eat microscopic prey.
The research team has already filed a patent in Germany, and in the future, they hope their creation will help curb a ubiquitous form of plastic pollution that many are unaware of.
Evolution doesn’t always take thousands or millions of years. Sometimes it happens right before our eyes.
Such is the case with the Anna’s hummingbird, a species that has undergone a dramatic transformation in just a few generations, all thanks to the advent of hummingbird feeders.
Beaks have grown longer and larger, and ranges have expanded to follow the feeders.
Astronomers from the Aryabhatta Research Institute of Observational Sciences (ARIES) in India and elsewhere have conducted a long-term photometric and spectroscopic study of a young stellar object known as V1180 Cassiopeiae. Results of the study, published December 23 on the arXiv preprint server, unveil the dual nature of this object.
Young stellar objects (YSOs) are stars in the early stages of evolution; in particular, protostars and pre-main sequence (PMS) stars. They are usually observed embedded in dense molecular clumps, environments containing plenty of molecular gas and interstellar dust.
Given that episodic accretion processes occur in YSOs, these objects may experience accretion-driven outbursts. Astronomers usually divide such events into EX Lup (also known as EXors) and FU Ori outbursts (or FUors). EXors are a few magnitudes in amplitude, and last from a few months to one or two years. FUors are more extreme and rare as they can be up to 5–6 magnitudes in amplitude and last from decades to even centuries.
In acute ischemic stroke, insulin resistance worsens outcomes by increasing blood-brain barrier permeability in the ischemic core.
Acute large‐vessel occlusion of head and neck severely affect quality of life. One of the critical pathological events associated with prognosis of acute ischemic stroke (AIS) is the disruption of the blood–brain barrier (BBB), a highly selective barrier maintaining the brain’s microenvironment.1 Ischemia causes BBB dysfunction,2 exacerbated by peripheral immune cell infiltration,3 leading to increased parenchymal injury, hemorrhage,4 and edema.4, 5 Therefore, accurately determining the evolution and severity of BBB permeability are crucial for prognostic evaluation in patients with AIS.
Research on BBB disruption in patients with AIS primarily focuses on pathological mechanisms and imaging evaluations. Numerous studies use animal models and cell culture experiments to elucidate the physiological and molecular bases of BBB disruption.2, 5, 6, 7, 8 Additionally, imaging techniques like magnetic resonance imaging are widely used to assess evolution of BBB permeability1, 9, 10, 11, 12 and demonstrate correlations between BBB damage, cerebral edema, hemorrhagic transformation, and poor prognosis. Despite significant advances, several issues remain unresolved. First, differences between animal models and human disease limit clinical applicability. Second, while magnetic resonance imaging is widely used to provide quantitative data on BBB disruption, they still face the limitations of being time consuming and inconvenient in the clinical environment. However, BBB disruption in patients with AIS based on computed tomography perfusion (CTP) needs further study.
Insulin resistance (IR) is linked to adverse cardiovascular13, 14 and metabolic outcomes.15, 16 Therefore, identifying patients with IR aids early risk stratification and management. The triglyceride–glucose (TyG) index, which combines fasting triglyceride and glucose levels, has been proposed as a marker of IR. Currently, research on the TyG index primarily focuses on type 2 diabetes,17 obesity,18 and cardiovascular diseases.19 Recent studies have found that an elevated TyG index is associated with higher stroke recurrence,19, 20 functional deterioration,21, 22 and death.23 However, whether the underlying mechanisms involved in the association of IR with stroke outcomes have not been fully understood. IR exacerbated vascular inflammation and endothelial dysfunction,24, 25, 26 which were critical contributors to BBB disruption in AIS. Previous studies have shown that metabolic dysregulation, including hypertriglyceridemia27 and hyperglycemia,28 aggravates BBB permeability by triggering oxidative stress and inflammatory pathways.29, 30 Specifically, IR leads to the generation of reactive oxygen species and the activation of NADPH oxidase, which contribute to oxidative stress and endothelial damage.30, 31 Inflammatory cytokines such as tumor necrosis factor‐α, interleukin‐1β, and interleukin‐6 are also elevated in the insulin‐resistant state, activating nuclear factor‐κB and Janus kinase signaling pathways that further compromise endothelial tight junction proteins such as occludin, claudin‐5, and zonula occludens‐1, crucial for BBB integrity.29, 32 These mechanisms are known to increase BBB permeability, facilitating the entry of harmful substances into the brain and contributing to worsened stroke outcomes. These findings indicated that the relationship between IR and stroke outcomes may be mediated by increased BBB permeability. However, the TyG index’s relationship with BBB disruption and outcomes in patients with AIS is not well studied.
Petitpas et al. dissect the single-cell transcriptome underlying the sequential steps of pre-malignant lesions and early anorectal cancer, mimicking disease evolution seen in patients, at the epithelial and immune level. They reveal a key epithelial-immune cell crosstalk involving IL-17-producing T lymphocytes and neutrophils as essential for the dysplasia-carcinoma progression.
Hair is a signature mammalian characteristic with versatile functions, including thermoregulation, protection from ultraviolet radiation, physical and chemical insults, sensation of pain, vibration and touch, and defence from predators.1–3 Human hair patterns, which feature prominently reduced body hair length combined with extremely long scalp hair,4–8 are an outlier among mammals. The likely original function of long scalp hair was to shield the sun-exposed head of upright-standing human ancestors. Long scalp hair probably reduced the amount of sweat secretion required to counter the total thermal load experienced by individuals from incoming solar radiation in equatorial Africa, and from endogenous muscle-generated heat during exercise.9 Tightly curled scalp hair is more efficacious at reducing heat gains compared with other hair shapes, and such hair probably represents the ancestral scalp hair form (Figure 1).9 Variability in hair shapes increased over time. These variations are thought to be associated with the dispersal of anatomically modern humans (AMHs) and accompanying effects of populational bottlenecks, admixture with Neanderthals and Denisovans, and adaptations to diverse environments at new geographic locations (Figure 1a).10 Extreme scalp hair length was probably universal across all African AMH populations and available for diverse functions, other than thermoregulation. In this sense, long scalp hair is an excellent example of exaptation, a form of evolutionary co-option,11 whereby it acquired secondary essential functions in communicating social cues.12 Under these conditions, unwanted hair loss triggered significant psychological stress in affected individuals.
Despite variations, both across different species and different body regions, hair typically has a finite length. A fully grown hair fibre commonly remains attached within its hair follicle (HF) until a new round of growth replaces it. In a typical adult human, approximately 90% of scalp HFs are in active growth (anagen) at any given time, which lasts for 5–7 years.13,14 This is in contrast to small (vellus) body HFs, which have short-lasting anagen, such as 22–28 days on the upper arm.15 When large (terminal) scalp HFs reduce in size, start growing vellus-like hairs, and/or stop growing for an extended period, they are considered to be entering a pathological state.
Elucidation of long scalp hair roles in human prehistory requires further investigation of its thermoregulatory benefit vs. the physical burden it may have caused by hindering vision and locomotion. Continuous hair growth is also metabolically expensive, requiring synthesis of large quantities of keratins and keratin-associated proteins.1,2,16,17 Conversely, highly visible long scalp hair effectively communicates a good state of fitness, whereas compromised hair growth implies poor nutrition and disease.17,18 Indeed, kwashiorkor, a disease caused by severe dietary protein deficit, features dramatic hair thinning and depigmentation.19 The ornamental potential of long hair enables the use of distinct hairstyles to signify a person’s social position, creativity and manual skills.20 Therefore, in prehistory, hair styling likely became an essential part of social communication, which probably further promoted long-hair trait selection.
A research team led by Prof. Liu Liangyun from the Aerospace Information Research Institute of the Chinese Academy of Sciences (AIRCAS) has produced the first comprehensive, high-resolution map of global city and town boundaries, offering a view of how urban boundaries have expanded and transformed over the past two decades. The new dataset—derived from 30-meter-resolution satellite observations—fills a long-standing gap in global urban studies.
Cities and towns are the dominant form of human settlement, playing a crucial role in sustaining ecological balance and advancing sustainable development. However, their complex spatial structures and rapid evolution have made high-resolution global urban boundary datasets scarce. To address this gap, the team integrated the GISD30 global impervious surface dynamic dataset with LandScan global population data to develop the Global City and Town Boundaries (GCTB) Dataset, which covers the period from 2000 to 2022.
Published in Scientific Data, the study details the researchers’ development of a morphology-oriented boundary delineation framework that combines kernel density estimation (KDE) and cellular automata (CA) to accurately map urban boundaries. When compared with multiple reference datasets, the GCTB Dataset showed the strongest agreement with the manually curated Atlas of Urban Expansion, achieving an R2 value of approximately 0.88—indicating high reliability in capturing urban extents.
Liu et al. report chromosome-level genomes of 11 species across 10 Polygonaceae genera (including four previously published genomes), which encompass diverse habitats. Integrating genomic and transcriptomic analyses, this study provides insights into the evolutionary adaptation strategies of Polygonaceae to thrive in various habitats.
As we evolve we become more intelligent, loving, creative and beautiful, so actually we are moving exponentially to have greater levels of the very properties we ascribe to god without limit. But we never become literally infinite but we are moving exponentially in that direction so that we become more God-like. Evolution is a spiritual process that moves us closer to God — Ray Kurzweil.
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