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Archive for the ‘biotech/medical’ category: Page 1885

Oct 31, 2019

Severe Vision Loss From Niacin (Vitamin B3) Can Be Reversed

Posted by in category: biotech/medical

I Believe it is the Sun-damaged parts of the body that cause the so-termed hives of Niacin. I knew this without seeing data on such I when taking my Niacin {even very small doses as I take averaging about 75 mg every other day} causes a disturbance in my eyes.


In a first-of-its-kind clinical report, retina specialists at the New York Eye and Ear Infirmary of Mount Sinai (NYEE) have shown that severe vision loss from a self-prescribed high dose of over-the-counter niacin is linked to injury of a specific cell type in a patient’s eye. The experts report that discontinuing the vitamin led to reversal of the condition and have published their findings in the fall issue of Journal of VitreoRetinal Diseases.

Niacin, also known as vitamin B3, is used for lowering hyperlipidemia or cholesterol and comes in prescription and over-the-counter forms; it can produce a rare toxic reaction called niacin-induced cystoid maculopathy, a form of retinal swelling.

Continue reading “Severe Vision Loss From Niacin (Vitamin B3) Can Be Reversed” »

Oct 31, 2019

Genome-scale CRISPR screens are efficient in non-homologous end-joining deficient cells

Posted by in category: biotech/medical

  • Article
  • Open Access
  • Published: 31 October 2019

Oct 31, 2019

Chinese scientists develop new material for treatment of liver cancer

Posted by in categories: biotech/medical, engineering, nanotechnology

Photo shows how the new nanomaterial can be used to treat liver cancer in mice. Experimental results prove that the material is efficient and safe in fighting tumors.(Photo provided to Xinhua)

Chinese scientists have invented a nanomaterial which has been proved effective in fighting liver tumors, providing new hope for cancer patients.

NANJING, Oct. 31 (Xinhua) — Chinese scientists have developed a nanometer material that can be used for liver cancer treatment, according to the Suzhou Institute of Biomedical Engineering and Technology under the Chinese Academy of Sciences Wednesday.

Oct 31, 2019

AI allows paralyzed person to ‘handwrite’ with his mind

Posted by in categories: biotech/medical, robotics/AI

Technology could nearly double writing speed for “locked-in” individuals.

Oct 30, 2019

Neural network reconstructs human thoughts from brain waves in real time

Posted by in categories: biotech/medical, robotics/AI

Researchers from Russian corporation Neurobotics and the Moscow Institute of Physics and Technology have found a way to visualize a person’s brain activity as actual images mimicking what they observe in real time. This will enable new post-stroke rehabilitation devices controlled by brain signals. The team published its research as a preprint on bioRxiv and posted a video online showing their “mind-reading” system at work.

To develop devices controlled by the brain and methods for cognitive disorder treatment and post-stroke rehabilitation, neurobiologists need to understand how the brain encodes information. A key aspect of this is studying the brain activity of people perceiving visual information, for example, while watching a video.

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Oct 30, 2019

Cancer Cells Converted into Harmless Fat Cells in Mice

Posted by in category: biotech/medical

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Oct 30, 2019

To survive in the human gut, bacteria need genetic ‘passcode’

Posted by in categories: biotech/medical, genetics

Humans’ guts are a dangerous place.

Bacteria living in people’s intestines pump out toxins to deter microbial intruders. But each person’s gut comes with its own set of toxins—an individualized “passcode” microbes must solve to survive, scientists report October 30, 2019, in the journal Nature.

The findings suggest that there’s not a one-size-fits-all approach to probiotics or live biotherapeutics, the microbial supplements that promote the growth of healthy bacteria, says study coauthor Joseph Mougous, a Howard Hughes Medical Institute (HHMI) Investigator at the University of Washington (UW). His team’s work is an early step toward figuring out how scientists might instead tailor beneficial microbes to different people.

Oct 30, 2019

‘Protein-Scaffolding’ for Repairing DNA Damage

Posted by in categories: biotech/medical, genetics

At the University of Copenhagen, researchers have discovered how some types of proteins stabilize damaged DNA and thereby preserve DNA function and integrity. This new finding also explains why people with inborn or acquired defects in certain proteins cannot keep their DNA stable and develop diseases such as cancer.

Every day, the body’s cells divide millions of times, and the maintenance of their identity requires that a mother cell passes complete genetic information to daughter cells without mistakes.

This is not a small task because our DNA is constantly under attack, both from the environment but also from the cell’s own metabolic activities. As a result, DNA strands can be broken at least once during each cell division cycle and this frequency can increase by certain lifestyles, such as smoking, or in individuals who are born with defects in DNA repair.

Oct 30, 2019

Serum elaidic acid levels tied to dementia, Alzheimer’s disease

Posted by in categories: biotech/medical, neuroscience

Higher serum levels of elaidic acid, an objective biomarker for industrial trans fat, are associated with an increased risk for developing all-cause dementia and Alzheimer disease, according to a study published online Oct. 23 in Neurology.

Takanori Honda, Ph.D., from Kyushu University in Fukuoka, Japan, and colleagues examined the prospective correlation between serum elaidic acid (trans 18:1 n-9) levels and incident dementia in 1,628 Japanese community residents aged 60 years and older without dementia. Participants underwent screening examination in 2002 to 2003 and were followed prospectively to November 2012.

The researchers found that 377 participants developed some type of dementia during follow-up. After adjustment for traditional risk factors, significant correlations were seen for higher serum elaidic acid levels with greater risk for developing all-cause dementia and Alzheimer disease. After adjustment for dietary factors, including total energy intake and intakes of saturated and , these associations remained significant. There was no significant correlation noted for serum elaidic acid levels and vascular dementia.

Oct 30, 2019

CNIO researchers obtain the first mice born with hyper-long telomeres and show that it is possible to extend life without any genetic modification

Posted by in categories: biotech/medical, genetics, life extension

A chance finding ten years ago led to the creation by researchers of the Spanish National Cancer Research Centre (CNIO) of the first mice born with much longer telomeres than normal in their species. Given the relationship between telomeres and ageing – telomeres shorten throughout life, so older organisms have shorter telomeres -, scientists launched a study generating mice in which 100% of their cells had hyper-long telomeres. The findings are published in Nature Communications and show only positive consequences: the animals with hyper-long live longer in better health, free from cancer and obesity. The most relevant thing for the authors is the fact that longevity has been significantly increased for the first time ever without any genetic modification.

“This finding supports the idea that, when it comes to determining longevity, genes are not the only thing to consider”, indicates Maria Blasco, Head of the CNIO Telomeres and Telomerase Group and intellectual author of the paper. “There is margin for extending life without altering the genes”.

Telomeres form the end of chromosomes, in the nucleus of each cell in the body. Their function is to protect the integrity of the genetic information in DNA. Whenever the cells divide the telomeres, they are shortened a little, so one of the main characteristics of ageing is the accumulation of short telomeres in cells. “Telomere shortening is considered to be one of the primary causes of ageing, given that short telomeres cause ageing of the organism and reduce longevity”, as the paper published in Nature Communications explains.