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Research teams have successfully regenerated mouse brain circuits using rat stem cells, showcasing a new method for restoring brain function and studying interspecies brain development.

These findings open up possibilities for treating neurological diseases and understanding brain evolution, while also hinting at future clinical applications and ethical challenges in using similar techniques for human organ transplantation.

Scientists regenerate neural pathways in mice with cells from rats.

Hacking my brain implant wouldn’t do much, he asserted, adding, “You might be able to see like some of the brain signals. You might be able to see some of the data that Neuralink’s collecting.”

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Norland Arbaugh did not specify the data that is being collected by Neuralink chip which is almost the size of a coin and contains thousands of electrodes that monitor and stimulate brain activity, as per the company. This information is digitally transmitted to researchers.

In February 2023, Frontiers in Science published an article titled “Organoid Intelligence (OI): The New Frontier in Biocomputing and Intelligence-in-a-Dish.” Since its publication, this research has sparked significant scientific interest and gained coverage in Forbes, Financial Times, Wall Street Journal, BBC, CNN and many others.

So, what is organoid intelligence and why has this article gathered such attention?

Continue reading “Brain in a dish — the potential of organoid intelligence and biological computing” »

About 170 billion cells are in the brain, and as they go about their regular tasks, they produce waste — a lot of it.

The brain appears to rely on synchronized waves to wash out waste products, including toxins associated with Alzheimer’s disease.

Neurogenetic disorders, such as neurofibromatosis type 1 (NF1), are diseases caused by a defect in one or more genes, which can sometimes result in cognitive and motor impairments. Better understanding the neural underpinning of these disorders and how they affect motor and cognitive abilities could contribute to the development of new treatment strategies.

Researchers at Stanford University and Washington University School of Medicine recently performed a study on mice aimed at investigating the impact of Nf1 gene mutations, which cause the NF1 neurogenetic disorder, on oligodendroglial plasticity, an adaptive brain process known to contribute to cognitive and motor functions.

Their findings, published in Nature Neuroscience, provide strong evidence that Nf1 mutations delay the development of oligodendroglia, a type of glial cells that support the functioning of the central nervous system, causing disruptions in motor learning.

From the dynamical point of view, most cognitive phenomena are hierarchical, transient and sequential. Such cognitive spatio-temporal processes can be represented by a set of sequential metastable dynamical states together with their associatedions: The state is quasi-stationary close to one metastable state before a rapidion to another state. Hence, we postulate that metastable states are the central players in cognitive information processing. Based on the analogy of quasiparticles as elementary units in physics, we introduce here the quantum of cognitive information dynamics, which we term “cognon”. A cognon, or dynamical unit of thought, is represented by a robust finite chain of metastable neural states. Cognons can be organized at multiple hierarchical levels and coordinate complex cognitive information representations.

MIT just produced three groundbreaking innovations that allowed them to map whole hemispheres of the human brain.

A parasitic fungus compels its insect host to behave in strange ways by hijacking secretory neurons and circadian pathways.

Current computing systems rely on Boolean logic and von Neumann architecture, where computing cells are based on high-speed electron-conducting complementary metal-oxide-semiconductor (CMOS) transistors. In contrast, ions play an essential role in biological neural computing. Compared with CMOS units, the synapse/neuron computing speed is much lower, but the human brain performs much better in many tasks such as pattern recognition and decision-making. Recently, ionic dynamics in oxide electrolyte-gated transistors have attracted increasing attention in the field of neuromorphic computing, which is more similar to the computing modality in the biological brain. In this review article, we start with the introduction of some ionic processes in biological brain computing. Then, electrolyte-gated ionic transistors, especially oxide ionic transistors, are briefly introduced. Later, we review the state-of-the-art progress in oxide electrolyte-gated transistors for ionic neuromorphic computing including dynamic synaptic plasticity emulation, spatiotemporal information processing, and artificial sensory neuron function implementation. Finally, we will address the current challenges and offer recommendations along with potential research directions.

Keywords: bio-inspired computing; ionic transistors; oxide semiconductors.

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