Lifeboat Foundation

Sinclair’s first episode. Enjoy.

In this episode, Dr. David Sinclair and co-host Matthew LaPlante discuss why we age. In doing so, they discuss organisms that have extreme longevity, the genes that control aging (mTOR, AMPK, Sirtuins), the role of sirtuin proteins as epigenetic regulators of aging, the process of “ex-differentiation” in which cells begin to lose their identity, and how all of this makes up the “Information Theory of Aging”, and the difference between “biological age” and “chronological age” and how we can measure biological age through DNA methylation clocks.

Continue reading “The Science Behind Why We Age | Lifespan with Dr. David Sinclair #1” »

Solar roofing provider GAF Energy announced today its Timberline Solar product uses solar shingles that you can nail to a roof.

GAF Energy, a division of Standard Industries, has made a solar roof system that integrated easily into traditional roofing processes in materials thanks to what it calls the first “nailable” solar shingle, the Timberline Solar Energy Shingle, which will be assembled domestically at GAF Energy’s manufacturing and R&D facility in San Jose, California. The company showed off the tech at the CES 2022 trade event in Las Vegas.

The project will create local American jobs and hopefully create more demand for residential clean energy. One of the challenges to date has been the need to house solar tiles on platforms that have to be attached to roofs, making a solar roof installation more complicated than putting on a traditional roof.

The vehicle showcased at the event was Model SD-03, which was a demonstration for the autonomous SD-05 which is currently under development. The company is aiming to kickstart its business with the latter after unveiling it as a flying taxi at the World Expo 2025 in Osaka. It is worth mentioning that SkyDrive has been tested for manned flights and recently got certified by the Japanese government. “SkyDrive recently advanced toward commercialization with the Japanese transportation ministry’s acceptance of its type certificate application, a major milestone that no other flying vehicle developers have reached in Japan”, the company said in its statement.

READ | Flying car completes first 35-minute inter-city flight test in Slovakia

The model released by SkyDrive at the CES 2022 is a driver-only vehicle that runs on electricity and is equipped with eight propellers. As per SkyDrive’s description of the vehicle, it can carry a maximum weight of 400 kg and is capable of cruising at 40–50 kilometres per hour for five to ten minutes. The company had revealed the first prototype of its eVTOL in 2018 and conducted the first manned flight in 2020. According to a report by Interesting Engineering, more companies such as Lilium and Volocopter are also planning to kickstart their flying car business this decade.

China’s technology giant Baidu is stepping up its efforts to expand in the autonomous vehicle segment with the commercial launch of a car model with Level-2 self-driving technology next year.

Last week the company’s CEO Robin Li confirmed that Jidu Auto, Baidu’s joint venture with local automaker Zhejiang Geely Holding Group, plans to begin mass production of its first electric vehicle (EV) with Level-2 autonomous driving technologies in 2023. The vehicle’s self-driving system is powered by Nvidia chips and is scheduled to be unveiled at the Beijing Auto Show in April of this year.

Baidu, known widely as an internet search engine and artificial intelligence company, is targeting the autonomous vehicle segment as a key growth industry and is in the process of rolling out autonomous taxi services across China.

Yanko Design.

Say goodbye to those hulking boxes in your living room with a single projector that might actually be doing too much.

Chief information security officers’ (CISOs) greatest challenge going into 2022 is countering the speed and severity of cyberattacks. The latest real-time monitoring and detection technologies improve the odds of thwarting an attack but aren’t foolproof. CISOs tell VentureBeat that bad actors avoid detection with first-line monitoring systems by modifying attacks on the fly. That’s cause for concern, especially with CISOs in financial services and health care.

Enterprises are in react mode

Enterprises fail to get the most value from threat monitoring, detection, and response cybersecurity strategies because they’re too focused on data collection and security monitoring alone. CISOs tell VentureBeat they’re capturing more telemetry (i.e., remote) data than ever, yet are short-staffed when it comes to deciphering it, which means they’re often in react mode.

The James Webb Telescope (JWST) has finished unfolding its primary mirror, ending a series of major deployments that took place over the span of two weeks. All of those deployments needed to go perfectly in order for the massive space telescope, which was decades in the making, to function.

The JWST has two primary mirror panels on either side that it will use to collect infrared light from the distant Universe. Each of them consists of three gold-plated hexagonal mirrors. Today, the rightmost wing was successfully unfurled, just one day after the leftmost wing was deployed. Now that both sides have been locked into place, this completes the array of 18 mirrors that makes up the 21-foot-wide JWST.

Congratulations, @NASAWebb! You are fully deployed!

DNA damage is constantly occurring in cells, either due to external sources or as a result of internal cellular metabolic reactions and physiological activities. Accurate repair of such DNA damages is critical to avoid mutations and chromosomal rearrangements linked to diseases including cancer, immunodeficiencies, neurodegeneration, and premature aging.

A team of researchers at Massachusetts General Hospital and the National Cancer Research Centre have identified a way to repair genetic damage and prevent DNA alterations using machine learning techniques.

The researchers state that it is possible to learn more about how cancer develops and how to fight it if we understand how DNA lesions originate and repair. Therefore, they hope that their discovery will help create better cancer treatments while also protecting our healthy cells.

Part 2 of TED Radio Hour episode Reshaping Evolution

Stem cells have long been heralded as a potential tool to treat illnesses. Nabiha Saklayen explains how it’s still early, but scientists are getting closer to turning this vision into a reality.