Lifeboat Foundation

One of the especially promising therapies to appear in the realm of anti-aging research involves a set of molecules known as Yamanaka factors, which scientists have deployed to rejuvenate aging cells, trigger muscle regeneration and tackle glaucoma. New research at the Salk Institute has sought to build on these short-term and specific use cases by demonstrating how these molecules can reverse signs of aging in middle-aged and elderly mice, with no evidence of health problems following the extended treatment.

The Yamanaka factors at the center of this study are a set of four reprogramming molecules that can reset the molecular clock found in the cells of the body. They do so by returning unique patterns of chemicals known as epigenetic markers, which evolve through aging, to their original states.

Continue reading “Anti-aging molecules safely reset mouse cells to youthful states” »

For researchers, a robot that’s easy to build, maintain, and deploy saves time, energy, and budget for the team’s primary goals. Learn what goes into an effecti… See more.

Researchers consider many factors when selecting a robot, but the most important factor is that the robot enables these teams to prioritize the research.

Two such certificates were part of the Nvidia hack attack haul we reported on last week.

Among all the sensitive hardware and driver data spilled by hacking extortion group Lapsus$, there were some expired but still usable Nvidia code-signing certificates.

Circa 2020

The short-term prospects for wind and solar power look rocky amid the economic upheaval of the coronavirus. But long term, renewables could emerge stronger than ever, especially if governments integrate support for clean energy into Covid-19 economic-recovery programs.

Circa 2012

Hydrogen sulphide (H2S) is a colourless gas with the odour of rotten eggs and has recently been recognized as a signal mediator in physiological activities related with the regulation of homeostasis, the vascular system and the inflammatory system. Here we show that H2S donors, including sodium hydrogen sulphide (NaHS), GYY 4137 and diallyltrisulfide (DATS), synergistically enhanced the anti-cancer effect of a green tea polyphenol (−)-epigallocatechin-3-O-gallate (EGCG) against multiple myeloma cells without affecting normal cells. NaHS significantly potentiated the anti-cancer effect of EGCG and prolonged survival in a mouse xenograft model. In this mechanism, H2S enhanced apoptotic cell death through cyclic guanosine monophosphate (cGMP)/acid sphingomyelinase pathway induced by EGCG.

Circa 2017 Egcg an active ingredient in green tea kills cancer.

Hydrogen sulphide (H2S) is a colourless gas with the odour of rotten eggs and has recently been recognized as a signal mediator in physiological activities related with the regulation of homeostasis, the vascular system and the inflammatory system. Here we show that H2S donors, including sodium hydrogen sulphide (NaHS), GYY 4137 and diallyltrisulfide (DATS), synergistically enhanced the anti-cancer effect of a green tea polyphenol (−)-epigallocatechin-3-O-gallate (EGCG) against multiple myeloma cells without affecting normal cells. NaHS significantly potentiated the anti-cancer effect of EGCG and prolonged survival in a mouse xenograft model. In this mechanism, H2S enhanced apoptotic cell death through cyclic guanosine monophosphate (cGMP)/acid sphingomyelinase pathway induced by EGCG.

To maintain peak efficiency, solar cells must be regularly cleaned of dust and other accumulated dirt. However, many panels are installed in high or hard-to-reach locations, which makes cleaning them difficult, time-consuming, and also simply dangerous. One solution is to use aerial drones to spray soapy water on dirty solar panels. However, these drones often run out of battery quite quickly. In addition, they also do not make direct contact with the panels, so they may not completely wash away dirt.

To solve these problems, a Belgian startup, ART Robotics, has developed HELIOS, an automated cleaning service for solar panels. It’s a fully autonomous system that can access difficult-to-reach places and eliminates dangerous and costly work.

Continue reading “Meet HELIOS, an automated solar panel cleaning system” »

It can create a lot of mist and it really looks like a magic smoke capacitor. I can say the project is a success. The idea is to add perfume to the water and give a good smell to your home. Just a few drops and it will give a very nice odor to the water mist. So this project is cool but is useful as well.

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A new study reveals that the iconic extinct Megalodon or megatooth shark grew to larger sizes in cooler environments than in warmer areas.

DePaul University paleobiology professor Kenshu Shimada and coauthors take a renewed look through time and space at the body size patterns of Otodus megalodon, the fossil shark that lived nearly worldwide roughly 15 to 3.6 million years ago. The new study appears in the international journal Historical Biology.

Otodus megalodon is commonly portrayed as a gigantic, monstrous shark in novels and films, such as the 2018 sci-fi thriller “The Meg.” In reality, this species is only known from teeth and vertebrae in the fossil record, although it is generally accepted scientifically that the species was indeed quite gigantic, growing to at least 50 feet (15 meters) and possibly as much as 65 feet (20 meters). The new study re-examined published records of geographic occurrences of Megalodon teeth along with their estimated total body lengths.