Lifeboat Foundation

Scientists have uncovered changes in neurological structure that could underlie the autism spectrum disorder known as Pitt Hopkins syndrome, thanks to the help of lab-grown brains developed from human cells.

Furthermore, the researchers were able to recover lost genetic functions through the use of two different gene therapy strategies – hinting at the possibility of treatments that could one day give those with the condition new options in improving their quality of life.

Pitt Hopkins syndrome is a neurodevelopmental condition stemming from a mutation in a DNA-management gene called transcription factor 4 (TCF4). Classed on the autism spectrum on account of its severe impact on motor skills and sensory integration, it’s a complex condition that presents with a range of severities.

What explains the dramatic progress from 20th-century to 21st-century AI, and how can the remaining limitations of current AI be overcome? The widely accepted narrative attributes this progress to massive increases in the quantity of computational and data resources available to support statistical learning in deep artificial neural networks. We show that an additional crucial factor is the development of a new type of computation. Neurocompositional computing adopts two principles that must be simultaneously respected to enable human-level cognition: the principles of Compositionality and Continuity. These have seemed irreconcilable until the recent mathematical discovery that compositionality can be realized not only through discrete methods of symbolic computing, but also through novel forms of continuous neural computing.

Consciousness defines our existence. It is, in a sense, all we really have, all we really are, The nature of consciousness has been pondered in many ways, in many cultures, for many years. But we still can’t quite fathom it.

Continue reading “Consciousness is the collapse of the wave function” »

To better automate reasoning, machines should ideally be able to systematically revise the view they have obtained about the world. Timotheus Kampik’s dissertation work presents mathematical reasoning approaches that strike a balance between retaining consistency with previously drawn conclusions and rejecting them in face of overwhelming new evidence.

When reasoning and when making decisions, humans are continuously revising what their view of the world is, by rejecting what they have previously considered true or desirable, and replacing it with an updated and ideally more useful perspective. Enabling machines to do so in a similar manner, but with logical precision, is a long-running line of artificial intelligence research.

In his dissertation, Timotheus advances this line of research by devising reasoning approaches that balance retaining previously drawn conclusions for the sake of ensuring consistency and revising them to accommodate new compelling evidence. To this end, he applies well-known mathematical principles from economic theory to formal argumentation, an approach to logic-based automated reasoning.

A new NASA climate simulation suggests that extremely large volcanic eruptions called “flood basalt eruptions” might significantly warm Earth’s climate and devastate the ozone layer that shields life from the Sun’s ultraviolet radiation.

It’s not often that a failed clinical trial leads to a scientific breakthrough.

When patients in the UK started showing adverse side effects during a cancer immunotherapy trial, researchers at La Jolla Institute for Immunology (LJI) Center for Cancer Immunotherapy and University of Liverpool went back through the data and worked with patient samples to see what went wrong.

Their findings, published recently in Nature, provide critical clues to why many immunotherapies trigger dangerous side effects—and point to a better strategy for treating patients with solid tumors.

Researchers from the U.S. Naval Research Laboratory (NRL) have demonstrated the feasibility of terrestrial microwave power beaming by transmitting 1.6 kilowatts (kW) over a distance of 1 kilometre (km) – the most significant advance for this technology in nearly 50 years.

Circa 2021

With SpaceX continuing the testing phase for Starship and enthusiasm spreading for an actual crewed flight to Mars, an interesting magnetic thrust rocket concept conceived by physicist Fatima Ebrahimi at the US Department of Energy’s (DOE) Princeton Plasma Physics Laboratory (PPPL) might make the mission much more cost effective.

Continue reading “Physicist designs magnetic thrust engine that could rocket us to the Red Planet” »

Recent Study on the effects of Dark Energy suggests expansion of the universe could in fact slow down and eventually reverse itself to eventually result in a “Big Crunch” billions of years from now. Such a theory had been proposed in the past but was previously rejected due to observed accelerating expansion attributed to Dark Energy.

The universe may stop expanding in just 100 million years if dark energy decays over time, a new study suggests.