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In the middle of the night, the world can sometimes feel like a dark place. Under the cover of darkness, negative thoughts have a way of drifting through your mind, and as you lie awake, staring at the ceiling, you might start craving guilty pleasures, like a cigarette or a carb-heavy meal.

Plenty of evidence suggests the human mind functions differently if it is awake at nighttime. Past midnight, negative emotions tend to draw our attention more than positive ones, dangerous ideas grow in appeal and inhibitions fall away.

Some researchers think the human circadian rhythm is heavily involved in these critical changes in function, as they outline in a new paper summarizing the evidence of how brain systems function differently after dark.

Continue reading “The Human Mind Is Not Meant to Be Awake After Midnight, Scientists Warn” | >

New York’s Gorbunova Aging Research Center team is encouraged by frailty results from SIRT6 activator trial.

SIRT6, the so-called “longevity sirtuin” has been making rather a name for itself.

SIRT6 is a protein with an important job. It is vital for both normal base excision repair and double-strand break repair of DNA damage – damage that can lead to genomic instability, which ultimately contributing to aging. These repairs decline with age but can be boosted with SIRT6 [1].

But SIRT6 has another string to its longevity bow; back in 2019, Vera Gorbunova, professor of biology at the University of Rochester, and her team, demonstrated an overexpression of SIRT6 protein leads to extended lifespan. The researchers also showed that the opposite is also true – a deficiency in SIRT6 can cause premature aging [2].

Continue reading “Longevity sirtuin clinical trial teases promising results” | >

The technology, even the interceptor systems already exists; We just need to integrate them. See my survey of the existing interceptors and how we could use them in conjunction with space launch rockets, such as a derivative of the Ares I-X which has already flown! Listen as I explain how many of these various interceptors you can fly in massive drone swarms from Ares I style boosters and larger variants.

Awesome deals for long term food supplies for those long missions to deep space (or prepping in case your spaceship crashes: See the Special Deals at My Patriot Supply: www.PrepWithGreg.com.

Continue reading “Stop Sarmat (Satan II), Hypersonics — All Missiles — the Details” | >

MPXV was first discovered during a nonfatal outbreak at an animal facility in Copenhagen, Denmark, in 1958. The facility received a continual supply of Asian monkeys (mostly M. fascicularis) and rhesus macaques (Macaca mulatta), which were used for polio vaccine research. The first outbreak occurred 2 months after the monkeys had been received and the second outbreak occurred 4 months after the initial outbreak. The outbreaks occurred in M. fascicularis that had arrived from Singapore. Upon arrival, monkeys were treated with antibiotics and appeared in satisfactory health.

Monkeypox virus (MPXV) was discovered in 1958 during an outbreak in an animal facility in Copenhagen, Denmark. Since its discovery, MPXV has revealed a propensity to infect and induce disease in a large number of animals within the mammalia class from pan-geographical locations. This finding has impeded the elucidation of the natural host, although the strongest candidates are African squirrels and/or other rodents. Experimentally, MPXV can infect animals via a variety of multiple different inoculation routes; however, the natural route of transmission is unknown and is likely to be somewhat species specific. In this review we have attempted to compile and discuss all published articles that describe experimental or natural infections with MPXV, dating from the initial discovery of the virus through to the year 2012. We further discuss the comparative disease courses and pathologies of the host species.

Keywords: aerosol, animals, infection, intrabronchial, intradermal, intramuscular, intranasal, intratracheal, intravenous, outbreak, primates, subcutaneous.

Orthopoxviruses (OPVs) have host specificities ranging from narrow (e.g., ectromelia and variola [VARV]) to broad (e.g., cowpox and vaccinia [VACV]). Monkeypox virus (MPXV) has a broad host-range and is capable of infecting many species from across the globe. In nature, the major environs of MPXV are restricted to the Congo Basin (CB) and West Africa (WA). The MPXV virion is a brick-shaped enveloped virus of 200–250 nm, characterized by surface tubules and a dumbbell-shaped core. Humans and highly susceptible nonhuman primates (NHPs) infected with MPXV have near identical clinical manifestations compared to humans infected with VARV. For humans, the only obvious difference in clinical signs is the absence of lymphadenopathy in smallpox patients [1,2].

Continue reading “A review of experimental and natural infections of animals with monkeypox virus between 1958 and 2012” | >

Advances in the fields of robotics, autonomous driving and computer vision have increased the need for highly performing sensors that can reliably collect data in different environmental conditions. This includes imagers that can operate at near-infrared wavelengths (i.e., 0.7–1.4 µm), thus potentially collecting high resolution images in complex or unfavorable atmospheric conditions, such as in the presence of rain, fog and smoke.

Researchers at Huazhong University of Science and Technology (HUST), HiSilicon Optoelectronics Co. Limited, and Optical Valley Laboratory have recently developed a near-infrared colloidal quantum dot (CQD) imager. This highly efficient imager was presented in a paper published in Nature Electronics.

“Our group was founded at Wuhan National Laboratory for Optoelectronics, HUST in 2012 and continuously conducts research on CQD materials and devices with Associate Prof. Jianbing Zhang,” Liang Gao, one of the researchers involved in the study, told TechXplore.

Continue reading “A highly efficient colloidal quantum dot imager that operates at near-infrared wavelengths” | >

Computer-based animators who are tasked with bringing to life imaginary worlds and characters are aided by simulators that can model the many possible ways an object or fluid might move through a physical space. Known as “solvers,” these simulators provide a significant head start on the work of animation. But there’s a catch. As computers have gotten faster, these solvers often create too many options for the animator to effectively sort through looking for just the right one.

“A simulator can return thousands of options. It’s so time consuming to sort through them that these helpful solvers can’t be used to their full potential,” said Purvi Goel, a doctoral candidate in at Stanford, who with her mentor, professor Doug James, has created a new approach to refine the search and narrow results to the most promising options.

Continue reading “A new, faster way to browse physics-based animations” | >

Threat actors are increasingly mimicking legitimate applications like Skype, Adobe Reader, and VLC Player as a means to abuse trust relationships and increase the likelihood of a successful social engineering attack.

Other most impersonated legitimate apps by icon include 7-Zip, TeamViewer, CCleaner, Microsoft Edge, Steam, Zoom, and WhatsApp, an analysis from VirusTotal has revealed.

“One of the simplest social engineering tricks we’ve seen involves making a malware sample seem a legitimate program,” VirusTotal said in a Tuesday report. “The icon of these programs is a critical feature used to convince victims that these programs are legitimate.”

Continue reading “VirusTotal Reveals Most Impersonated Software in Malware Attacks” | >
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