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Jun 25, 2023

A jump through time — new technique rewinds the age of skin cells by 30 years

Posted by in categories: biotech/medical, genetics, life extension

Research from the Babraham Institute has developed a method to ‘time jump’ human skin cells by 30 years, turning back the ageing clock for cells without losing their specialised function. Work by researchers in the Institute’s Epigenetics research programme has been able to partly restore the function of older cells, as well as rejuvenating the molecular measures of biological age. The research is published today in the journal eLife and whilst at an early stage of exploration, it could revolutionise regenerative medicine.

What is regenerative medicine?

As we age, our cells’ ability to function declines and the genome accumulates marks of ageing. Regenerative biology aims to repair or replace cells including old ones. One of the most important tools in regenerative biology is our ability to create ‘induced’ stem cells. The process is a result of several steps, each erasing some of the marks that make cells specialised. In theory, these stem cells have the potential to become any cell type, but scientists aren’t yet able to reliably recreate the conditions to re-differentiate stem cells into all cell types.

Jun 24, 2023

Science Saturday: Study finds senescent immune cells promote lung tumor growth

Posted by in categories: biotech/medical, science

Researchers have discovered a type of white blood cell in the lungs, called senescent macrophages, that promote tumor growth.

Jun 24, 2023

MIT’s Nematic Leap: Physicists Discover a New Switch for Superconductivity

Posted by in categories: materials, particle physics

MIT researchers have found a new mechanism by which the superconductor iron selenide transitions into a superconducting state. Unlike other iron-based superconductors, iron selenide’s transition involves a collective shift in atoms’ orbital energy, not atomic spins. This breakthrough opens up new possibilities for discovering unconventional superconductors.

Under certain conditions — usually exceedingly cold ones — some materials shift their structure to unlock new, superconducting behavior. This structural shift is known as a “nematic transition,” and physicists suspect that it offers a new way to drive materials into a superconducting state where electrons can flow entirely friction-free.

But what exactly drives this transition in the first place? The answer could help scientists improve existing superconductors and discover new ones.

Jun 24, 2023

Pepsi Reveals Tesla Semi Operations Details With Real Mileage Numbers

Posted by in category: transportation

Three days ago CNBC reporters visited Pepsi’s Frito-Lay facility in Modesto, California, where it is using Tesla Semi’s new electric trucks. CNBC wanted to see whether the Semis live up to the hype. Watching that report I learned a couple of very interesting details about Pepsi Tesla Semi operations and here I wanted to share with you.

Jun 24, 2023

Tesla is removing one of the last barriers to EV ownership

Posted by in category: futurism

Tesla is preparing to open to its previously exclusive Supercharger network via partnerships with Ford, GM, and Rivian. That could help EV adoption.

Jun 24, 2023

Alan Turing and the Limits of Computation

Posted by in categories: biological, mathematics, robotics/AI

Note: June 23 is Alan Turing’s birth anniversary.

Alan Turing wore many scientific hats in his lifetime: a code-breaker in World War II, a prophetic figure of artificial intelligence (AI), a pioneer of theoretical biology, and a founding figure of theoretical computer science. While the former of his roles continue to catch the fancy of popular culture, his fundamental contribution to the development of computing as a mathematical discipline is possibly where his significant scientific impact persists to date.

Jun 24, 2023

Physicists Discover a New State of Matter Hidden in The Quantum World

Posted by in categories: particle physics, quantum physics, space

You’re familiar with the states of matter we encounter daily – such as solid, liquid, and gas – but in more exotic and extreme conditions, new states can appear, and scientists from the US and China just found one.

They’re calling it the chiral bose-liquid state, and as with every new arrangement of particles we discover, it can tell us more about the fabric and the mechanisms of the Universe around us – and in particular, at the super-small quantum scale.

States of matter describe how particles can interact with one another, giving rise to structures and various ways of behaving. Lock atoms in place, and you have a solid. Allow them to flow, you have a liquid or gas. Force charged partnerships apart, you have a plasma.

Jun 24, 2023

New Study Reveals A Hidden Mechanism for Controlling A Cell’s Molecules

Posted by in category: biotech/medical

Some mutations were like a tax rebate and raised the propensity of TAR to adopt its biologically active structures, while other modifications raised the tax and decreased the odds that TAR would adopt a biologically active structure.

Hidden mechanism may lead to new drugs

“What we found was a hidden mechanism for controlling the activity of a molecule in a cell,” says Al-Hashimi. By altering the propensity of TAR to form biologically active states—by changing the tax rate—the researchers could fine-tune the molecule’s activity in cells.

Jun 24, 2023

Porsche is developing an exclusive electric sports boat

Posted by in categories: sustainability, transportation

With ambitious goals of being a leader in sustainable mobility, Porsche has joined forces with Frauscher Shipyard in Austria to engineer an electric yacht that is also intended to set standards on the water with its typical Porsche E-Performance. The vehicle is called the Frauscher x Porsche 850 Fantom Air highlighting the collaboration that made it possible.


Porsche.

This is according to a press release by the carmaker published on Saturday.

Continue reading “Porsche is developing an exclusive electric sports boat” »

Jun 24, 2023

YouTuber turns a Raspberry Pi-powered truck into a giant printer

Posted by in categories: computing, transportation

Many people love the Raspberry Pi (us included). Not only are the computing boards cheap, but you can do so much with them. Wild, wonderful projects spring up all the time with RPi boards as a central piece. The latest creation to catch our eye might just rank as one of the most astonishing: a truck transformed into a dot matrix printer.

As spotted by Tom’s Hardware, YouTuber Ryder Damen (who runs the channel Ryder Calm Down) uses a Raspberry Pi to control his homebrew “printer,” which involves a pickup truck, water, and a whole array of gear to spell out messages on the ground. Damen calls it “skywriting, but on the road.”

In the video, Damen explains how the idea came to be (watching trucks paint markers on the road), as well as the process of constructing the “printer” and the materials used. A plywood and a trailer hitch form the frame of the rig, with solenoids, valves, and hoses then mounted to the wood to serve as printer parts. The solenoids control the valves—when 12V current is applied to them, they open. Meanwhile, the hoses split the water flow from a central point (a pump and a bucket full of water) to each valve.