Lifeboat Foundation

For those interested in life extension and bionic / cyborg type enhancements, this CMU Robotics Institute Seminar gives an overview of the background and current developments in artificial vision. José Alain Sahel MD is a world leading ophthalmologist with a lengthy bio and numerous honors and appointments.

In the future, if you’re going blind, these sight restoration technologies may be used to remediate your vision loss.

Three major ideas are covered. 1) Implanting arrays of tiny 3-color LEDs under a failed retina to stimulate still-okay cells, and 2) using gene therapy to express a novel photoreceptor, borrowed from algae, to restore a form of sight to failed cells. These can be done together. Lots of studies in mice, primates, and humans. Some coverage is also given to 3) directly implanting electronics in the brain to send complete images to vision centers, but this is still at an early stage.

Continue reading “Artificial Vision, Artificial Retina, Optogenetics, José Alain Sahel MD, CMU RI Seminar” »

Nice. My friend Alex Zhavoronkov will appreciate this article.

Feb. 16 (UPI) — Researchers at McGill University in Montreal have found that targeting the internal circadian or biological clock of cancer cells can affect growth.

Most cells in the human body have an internal clock that sets a rhythm for activities of organs depending on the time of day. However, this internal clock in cancer cells does not function at all or malfunctions.

Continue reading “Study finds targeting biological clock in cells slows cancer” »

Not too shock by this given other transplant patient’s stories of memories, etc.

There are a lot of outrageous claims being made within the halls of neuroscience and artificial intelligence. Whether exaggerations, wishful thinking, the dreams of the egocentric and megalomaniacal to be immortal, or just drumming up funding for a never-ending round of “scientific investigation,” the year 2045 seems to always be cited as a target date.

Continue reading “Company Claims Brain Transplants Could Bring Back the Dead by 2045” »

New research on Parkinson and holds additional insights in cell & neuro technology.

Autophagy functions as a main route for the degradation of superfluous and damaged constituents of the cytoplasm. Defects in autophagy are implicated in the development of various age-dependent degenerative disorders such as cancer, neurodegeneration and tissue atrophy, and in accelerated aging. To promote basal levels of the process in pathological settings, we previously screened a small molecule library for novel autophagy-enhancing factors that inhibit the myotubularin-related phosphatase MTMR14/Jumpy, a negative regulator of autophagic membrane formation. Here we identify AUTEN-99 (autophagy enhancer-99), which activates autophagy in cell cultures and animal models. AUTEN-99 appears to effectively penetrate through the blood-brain barrier, and impedes the progression of neurodegenerative symptoms in Drosophila models of Parkinson’s and Huntington’s diseases. Furthermore, the molecule increases the survival of isolated neurons under normal and oxidative stress-induced conditions. Thus, AUTEN-99 serves as a potent neuroprotective drug candidate for preventing and treating diverse neurodegenerative pathologies, and may promote healthy aging.

Another new interface method.

Engineering researchers at The University of Texas at Austin have designed ultra-flexible, nanoelectronic thread (NET) brain probes that can achieve more reliable long-term neural recording than existing probes and don’t elicit scar formation when implanted.

The researchers described their findings in a research article published in Science Advances (“Ultraflexible nanoelectronic probes form reliable, glial scar–free neural integration”).

Continue reading “Nanoelectronic thread probes form reliable, scar-free integration with the brain” »

A neuropeptide called orexin has been shown to prevent mice from dying from septic shock.

The problems that I have seen when limiting the topic of quantum mechanics to the human mind topic is that the relationship around Quantum Mechanics to biology is missed completely. For example, it has only be in the recent few years that scientists began to understand Quantum Mechanics Action of ELF electromagnetic fields and its relationship to human cells. And, this find has open valuable research in how cells can (through electromagnetic fields can spin a low temperatures) mimic telepathy communicating between the human cells.

Nobody understands what consciousness is or how it works. Nobody understands quantum mechanics either. Could that be more than coincidence?

Scientists have discovered a groundbreaking immunotherapy combination that kills brain cancer, promotes long-term immunity and is highly effective against breast cancer and myeloma.

Researchers at the Children’s Hospital of Eastern Ontario (CHEO) in Ottawa had the promising findings published Wednesday in the journal ‘Nature Communications’.

The study outlines how the team developed a unique combination of drugs known as SMAC Mimetics and immune checkpoint inhibitors (ICIs) that produce high kill rates for cancer tumor cells in mice.

This video is part of a series on genius, in proud collaboration with 92Y’s 7 Days of Genius Festival.

In the late 1990s, scientists thought they were close to locating specific genes that controlled for human intelligence in all its manifestations: musical genius, analytical acumen, physical prowess, etc. But the truth turns out to be more complicated, says Harvard psychologist and linguist Steven Pinker. There are many genes — perhaps thousands — that affect human intelligence, and while manipulating them may have predictable benefits, the adverse consequences remain unpredictable. Thus experimenting with our so-called intelligence genes will likely be met with high levels of skepticism in caution. It’s proof, says Pinker, that technological advancement doesn’t always march to the drum beat of inexorable forward progress.