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New work led by researchers at the University of Exeter, King’s College London, the London School of Hygiene and Tropical Medicine and the University of Liverpool has found that women who had at least one contact with mental health services in the seven years prior to their pregnancy were at increased risk of preterm birth.

The study, “Obstetric and neonatal outcomes in pregnant women with and without a history of specialist mental health care: a national population-based cohort study using linked routinely collected data in England,” published in Lancet Psychiatry, analyzed data from more than two million pregnant women, and found that one in 10 women who had used mental health services before their pregnancy had a preterm birth, compared to one in 15 in those who had not.

Researchers also found that women who had used mental health services faced a higher risk of giving birth to a baby that was small for its gestational age, increasing from 65 per 1,000 births in women who had not used mental health services to 75 per 1,000 births in women who had.

We’re seeing major advancements in tech that can decode brain signals, interpreting neural activity to reveal what’s on someone’s mind, what they want to say, or – in the case of a new study – which song they’re listening to.

US researchers have been able to reconstruct a “recognizable version” of a Pink Floyd song based on the pulses of activity moving through a specific part of the brain’s temporal lobe in volunteers as they listened to the hit Another Brick in the Wall Part 1.

Continue reading “Scientists Recreate Classic Pink Floyd Track From The Brains of Listeners” »

Dr. Howard Tucker has been practicing medicine and neurology for over 75 years. The 101-year-old doctor shares his No. 1 secret for keeping your brain sharp.

Blood vessels form the transportation network within our bodies. They are streets where red and white blood cells drive. They are the delivery system to oxygenate our brain and other vital organs and muscles. There are other highways in our bodies such as our nervous and lymphatic systems, but blood vessels are the ones that are central to healthy heart function and keeping our brain supplied with oxygen. When blood vessels are compromised we can suffer a stroke, heart attack, aneurysm or die.

When usual causes of heart attacks are blocked coronary arteries. The coronary arteries supply blood and oxygen to the heart. When partially blocked people experience symptoms like angina. When blocked they can suffer a myocardial infarction, the fancy name for a heart attack.

Today, harvested blood vessel grafts from human donors or the patient are used for bypassing coronary blood vessel blockages. But researchers at the University of Melbourne believe that fabricated blood vessel tissue that can be shaped to any need would be an effective substitute for existing grafts. The team in its search for a graft alternative has combined a variety of materials and living tissue with a fabrication technique to create complex blood vessels that can serve multiple purposes.

M3GAN wasn’t malicious. It followed its programming, but without any care or respect for other beings—ultimately including Cady. In a sense, as it engaged with the physical world, M3GAN became an AI sociopath.

Sociopathic AI isn’t just a topic explored in Hollywood. To Dr. Leonardo Christov-Moore at the University of Southern California and colleagues, it’s high time we build artificial empathy into AI—and nip any antisocial behaviors in the bud.

In an essay published last week in Science Robotics, the team argued for a neuroscience perspective to embed empathy into lines of code. The key is to add “gut instincts” for survival—for example, the need to avoid physical pain. With a sense of how it may be “hurt,” an AI agent could then map that knowledge onto others. It’s similar to the way humans gauge each others’ feelings: I understand and feel your pain because I’ve been there before.

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In this “Ask Me Anything” (AMA) episode, Peter delves into the realm of genetics, unraveling its connection to disease and emphasizing the value of understanding one’s genetic risks. He elucidates essential background knowledge on genetics before delving into the myriad reasons why individuals might consider genetic testing. Peter differentiates scenarios where genetic testing provides genuine insights from those where it may not be as useful. From there, Peter explores a comprehensive comparison of commercial direct-to-consumer genetic tests, providing insights on interpreting results and identifying the standout options for gaining insights into personal health.

Continue reading “Genetics: how they impact disease risk, what you can do about it, testing & more [AMA 50 sneak peek]” »

A comprehensive new study provides evidence that various personality traits and cognitive abilities are connected. This means that if someone is good at a certain cognitive task, it can give hints about their personality traits, and vice versa.

For example, being skilled in math could indicate having a more open-minded approach to new ideas, but might also be associated with lower levels of politeness. These connections can help us understand why people are different in how they think and act.

The research has been published in the Proceedings of the National Academy of Sciences.

University of Michigan researchers published a study detailing a new method for making brain organoids, or miniature lab-grown brains used in neuroscience research, last June. Previously, the most common method for creating human brain organoids relied on Matrigel — a substance made of cells from mouse sarcomas — to provide structure for the organoids, but the new method uses an engineered extracellular matrix composed of human-derived proteins.

The lack of cells from other species in the new organoids means they more closely resemble actual human brains, opening up research possibilities on neurodegenerative diseases such as Alzheimer’s and Parkinson’s. U-M alum Ayse Muñiz, who worked on the research as part of her Ph.D. thesis while at the University, said in an interview with The Michigan Daily that having organoids with only human cells is advantageous for translational research — the process of turning knowledge from lab research into something with real-world applications.

“When you’re doing translational research, having contamination from other species will limit your ability to translate this into the clinic,” Muñiz said. “The presence of other species basically elicits immunogenic responses, and can just be a limitation for scale and other things like that. And so here now that you’ve taken that out, it makes the path to translation a lot easier.”

I first posted about Orgaanoids for the heart, beause I have a family member with heart problems, and I know how the innovation is a game changer. I like to think of myself as a futurist, and being ahead of most everyone. My post about Mastodon proves such…oh wait someone else posted it and threads uses the same ActivityPub protocol that is Mastodon. I should get Him to repost it if I know Him 🙄, while as if I thought it. Let us always embrace the future, and futurists. 😁

For over a century, scientists have dreamed of growing human organs sans humans. This technology could put an end to the scarcity of organs for transplants. But that’s just the tip of the iceberg. The capability to grow fully functional organs would revolutionize research. For example, scientists could observe mysterious biological processes, such as how human cells and organs develop a disease and respond (or fail to respond) to medication without involving human subjects.

As described in the aforementioned Nature paper, Żernicka-Goetz and her team mimicked the embryonic environment by mixing these three types of stem cells from mice. Amazingly, the stem cells self-organized into structures and progressed through the successive developmental stages until they had beating hearts and the foundations of the brain.

Continue reading “The organoid revolution: From a breast in Jello to a synthetic embryo” »