Lifeboat Foundation

A revolutionary new DNA tool could help take humanity a step closer to eternal life. The device (pictured) pioneers a new technique that makes it cheaper and easier to synthesise genes ‘overnight’, say scientists — a process that normally takes several days.

Scientists at the University of California at Berkeley said it could lead to ‘DNA printers’ in research labs that work like the 3D printers in many modern workshops.

Continue reading “Genetic tool could let scientists create new DNA ‘overnight’ that may help humans live forever” »

Humanity is made of individuals; preserving the life of individuals preserves humanity. Thus, life extension and the preservation of our species aren’t incompatible.

What is it that really matters: preserving individual lives or preserving humanity? Is it more important to grant individuals the option to live as long as they’d like in good health, or is it more important to ensure the preservation of our species? This sort of question isn’t unheard of in the context of discussions of pros and cons of rejuvenation biotechnology; at times, when presented with the possibility of indefinite lifespans, some people reply that focusing on the preservation of our species is more important. This observation is reminiscent of the “other priorities” objection, and one could respond to it in the same way. However, this issue is also worth examining from other angles.

Quick comeback: the two goals aren’t incompatible

Continue reading “Humanity first, or individuals first?” »

For the June edition of Journal Club, we will be taking a look at the recent paper entitled “Changes at the nuclear lamina alter binding of pioneer factor Foxa2 in aged liver”.

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https://onlinelibrary.wiley.com/doi/abs/10.1111/acel.12742

The exponential potential of longevity technologies.

Jim Mellon became a billionaire by pouncing on a wide variety of opportunities, from the dawn of business privatization in Russia to uranium mining in Africa and real estate in Germany. But all of that might eventually look small, he says, compared to the money to be made in the next decade or so from biotechnologies that will increase human longevity well past 100.

The British investor is so enthusiastic about these technologies that he co-authored a 2017 book about them, Juvenescence: Investing in the Age of Longevity, and launched a company, Juvenescence Ltd., to capitalize on them. “Juvenescence” is a real word — it’s the state of being youthful. Says Mellon, who is 61: “I’m hoping that this stuff works on me as well as on my portfolio.”

Continue reading “Longevity, the Greatest Investment Opportunity of All Time” »

An interview with Dr. Vadim Gladyshev, Harvard University.

We have recently had occasion to have a chat with Dr. Vadim Gladyshev, Professor of Medicine and Director of Redox Medicine at Brigham and Women’s Hospital, Harvard Medical School, in Boston, Massachusetts. He is an expert in aging and redox biology and is known for his characterization of the human selenoproteome. His research laboratory focuses on comparative genomics, selenoproteins, redox biology, and, naturally, aging and lifespan control.

Dr. Gladyshev graduated from Moscow State University, in Moscow, Russia; his postdoctoral studies in the 1990s took place at the National Heart, Lung, and Blood Institute, and the National Cancer Institute, in Bethesda, Maryland. Even when he was young, he was very much interested in chemistry and experimental science: he twice won the regional Olympiad in chemistry and graduated from high school with a gold medal. He also graduated with the highest honors from Moscow State University. This enviable track record is even more impressive considering that Dr. Gladyshev completed music school and high school at the same time and became a chess player equivalent to national master during his college years.

Continue reading “Dr. Vadim Gladyshev – Harvard University” »

At least in the developed world, cancer, heart diseases, and neurodegenerative diseases are among the greatest causes of mortality. One emerging and very promising way to prevent or cure these diseases is through bio-nanotechnology.

Nanotechnology is the design, synthesis and application of materials or devices that are on the nanometer scale (one billionth of a meter). Due to the small scale of these devices, they can have many beneficial applications, both in industry and medicine. The use of nanodevices in medicine is called nanomedicine. Here, we will look at some applications of nanomedicine in curing or preventing the diseases that are most likely to kill us.

Today we will be taking a look at some of the stories people tell themselves to help them pretend aging is not a problem.

If you ask most people what they think about aging, they will shrug their shoulders and say that it is a natural process. With complete tranquility on their faces, they will agree that, yes, in old age, we are haunted by many diseases, but nothing can be done about it, so it makes no sense to worry about it while you are young and healthy. Just live your life.

Then, the conversation will turn towards an even stranger direction: they will start looking for something good about aging – for example, that it ensures a change of generations, prevents society from becoming stuck in obsolete ideas, and, in general, is the engine of evolution. They’ll explain that the notion of death gives meaning to life and makes us accomplish as much as possible in the little time we have.

Continue reading “Is aging not scary? The children’s tales that are killing us” »

It seems reasonable that people would want to maximize various aspects of life if they were given the opportunity to do so, whether it’s the pleasure they feel, how intelligent they are, or how much personal freedom they have. In actuality, people around the world seem to aspire for more moderate levels of these and other traits, according to findings published in Psychological Science, a journal of the Association for Psychological Science.

“Our research shows that people’s sense of perfection is surprisingly modest,” says psychological scientist Matthew J. Hornsey of the University of Queensland, first author on the research. “People wanted to have positive qualities, such as health and happiness, but not to the exclusion of other darker experiences—they wanted about 75% of a good thing.”

Furthermore, people said, on average, that they ideally wanted to live until they were 90 years old, which is only slightly higher than the current average life expectancy. Even when participants imagined that they could take a magic pill guaranteeing eternal youth, their ideal life expectancy increased by only a few decades, to a median of 120 years old. And when people were invited to choose their ideal IQ, the median score was about 130—a score that would classify someone as smart, but not a genius.

Continue reading “Around the world, people have surprisingly modest notions of the ‘ideal’ life” »

Glorious news! Undoing Aging 2019 has been announced today hosted by Forever Healthy and the SENS Research Foundation. We loved being there last year and bringing the community all the news and interviews from the event and we are delighted to see it is making a return in 2019.

We are very pleased to see that there will be a return of the successful Undoing Aging Conference in 2019. We attended the conference earlier this year, and as we reported at the time, it was a really positive experience.

This was, from the outset, a serious conference focused on the rapid science and research going on in the field and was just the kind of conference that the community needed. The conference was a superb mixture of respected researchers, investors, and thought leaders from the community, and it had no hint of the snake oil that has plagued our community in past years.

Continue reading “Undoing Aging 2019 is Confirmed” »