Lifeboat Foundation

Innovation is key for developing the future of agriculture and sometimes it comes from unlikely places.

The NASA Artemis Mission is working to develop space exploration, but here on Earth, they are partnering with the University of California Berkeley to use Land Satellite Seven to benefit agriculture.

According to NASA Administrator Jim Bridenstine, “We can use that data from space and combine it with weather stations from Earth, and we can get very precise evapotranspiration measurements, down to a quarter of an acre. What that means is we can provide farmers with very specific irrigation plans.”

Continue reading “NASA’s Artemis Mission looks to help better agriculture” »

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Maximal lifespan in calorie restricted (CR) mice can range from 45 — 55 months. In this video, I present data for 3 studies on rapamycin-can it beat CR for maximal lifespan?

Scientists at the Department of Energy’s (DOE) Argonne National Laboratory have developed a light-activated coating for filtration membranes—the kind used in water treatment facilities, at semiconductor manufacturing sites and within the food and beverage industry—to make them self-cleaning, eliminating the need to shut systems down in order to repair them.

Cheap and effective, water filtration membranes have been around for years but have always been vulnerable to clogging from organic and inorganic materials that stop up its pores over time, a phenomenon known as fouling.

“Anything you stick in water is going to become fouled sooner or later,” said Argonne senior scientist Seth Darling.

Scientists investigating Alzheimer’s treatments at the Salk Institute have uncovered some key mechanisms that enable an experimental drug to reverse memory loss in mouse models of the disease. The discovery not only bodes well for the possibility of clinical trials, but provides researchers with a new target to consider in the wider development of compounds to counter the degenerative effects of the condition.

The research centers on a drug called CMS121, which is a synthetic version of a chemical called fisetin that occurs naturally in fruits and vegetables. The Salk team’s previous studies concerning CMS121 have produced some very promising results, with one paper published last year describing how the drug influences age-related metabolic pathways in the brain, protecting against the type of degeneration associated with Alzheimer’s. This followed earlier studies demonstrating how fisetin can prevent memory loss in mice engineered to develop Alzheimer’s.

Work continues at Salk to understand how exactly fisetin and the synthetic variant CMS121 produces these anti-aging effects on the brain. In their latest study, the researchers again turned to mice engineered to develop Alzheimer’s, which were administered daily doses of CMS121 from the age of nine months. This is the equivalent to middle age in humans, with the mice already exhibiting learning and memory problems before the treatment began.

Bay Area based artist-inventor and amateur mycologist Phil Ross has an international patent pending on a method of producing fungus as a sustainable construction material. It may be surprising to hear that a biodegradable, durable, and non-toxic building material is on sale in the vegetable aisle at the supermarket. However, it’s not the tasty caps that Ross is after, but the root-like fibers of mushrooms form an enormous underground tangle called mycelium. Dried mycelium forms a lightweight mold and water resistant fire-proof material that is an effective insulator. It is also very sturdy stuff. Bob Engels of Gourmet Mushrooms notes, “Hardened steel blades on equipment at our farm need regular attention following their encounters with these massed threads of hyphae.”

Ross reported that multiple saw blades and metal files were destroyed while shaping the five hundred mycelium bricks he grew into an archway. The archway was a 6×6 foot sculpture titled Mycotectural Alpha, and was likely the first man-made structure made entirely out of mushrooms. Others have taken notice of the potential of fungus—a new start-up called Evocative Design producing mycelium alternatives to styrofoam and insulation material has received grants from the National Science Foundation, the Environmental Protection Agency, and the Department of Agriculture.

Ross’s “biotechnical” artwork encompasses drawings, paintings, sculptures, prototypes, and extensive materials research. Over the past 15 years he has been experimenting with fungus, growing and shaping mushrooms in sterile laboratory-like environments, even learning to make his own air filters to provide the necessary clean air. He says mycelium bricks can be grown in about a week from a mixture poured into a mold, but the more organic-looking mushroom sculptures that are created by adding or subtracting gas or air from their growing environment can take years to create. the artist explains how the “myotecture” bricks are made:

Circa 2014

The waste fibres from hemp crops can be transformed into high-performance energy storage devices, scientists say.

They “cooked” cannabis bark into carbon nanosheets and built supercapacitors “on a par with or better than graphene” — the industry gold standard.

Continue reading “Hemp fibres ‘better than graphene’” »

Ogba Educational Clinic promoting tech in Africa.

An update to Google’s blindness assistance app adds AI image recognition for food shopping.

Ensuring nobody goes to bed hungry.

🔎 Learn more about the state of global hunger: https://buff.ly/3eZEypq

Lactoferrin is a nutrient classically found in mammalian milk. It binds iron and is transferred via a variety of receptors into and between cells, serum, bile, and cerebrospinal fluid. It has important immunological properties, and is both antibacterial and antiviral. In particular, there is evidence that it can bind to at least some of the receptors used by coronaviruses and thereby block their entry. Of importance are Heparan Sulfate Proteoglycans (HSPGs) and the host receptor angiotensin-converting enzyme 2 (ACE2), as based on other activities lactoferrin might prevent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) from attaching to the host cells. Lactoferrin (and more specifically enteric-coated LF because of increased bioavailability) may consequently be of preventive and therapeutic value during the present COVID-19 pandemic.

Lactoferrin (LF) or lactotransferrin has recently come under the spotlight, particularly with regards to the new coronavirus pandemic that started in 2019 (COVID-19). Diet and supplements support a well-functioning immune system, and favorably influence the body’s ability to fight infection. Although LF is produced by the body itself, as a secretion by exocrine glands (such as maternal milk or tears) and secondary granules of human neutrophils (1), it can also be taken as a supplement, where it then acts as nutraceutical or functional food. Our particular focus is on its role as an oral supplement. Here we also collate some of the evidence that shows how LF may be an important nutrient to support host immunity, including as an antibacterial and antiviral agent, but particularly with the current COVID-19 pandemic in mind.

We summarize what is already known about LF, including its immunological properties, as well as its antibacterial and antiviral activities. We also discuss how LF uses Heparan Sulfate Proteoglycans (HSPGs) on cell surfaces to facilitate entry. This is of particular importance to coronaviruses, as these viruses are considered to bind to the host cell by attaching first to HSPGs using them as preliminary docking sites on the host cell surface. LF is known to interfere with some of the receptors used by coronaviruses, it may thus contribute to the prevention and treatment of SARS CoV-2 infections. In COVID-19 infection, LF may therefore have a role to play, not only sequestering iron and inflammatory molecules that are severely increased during the cytokine burst, but also possibly in assisting by occupying receptors and HSPGs.