A new experimental drug for cancer was discovered to foster nerve regeneration after spinal trauma.
𝙎𝙘𝙞𝙚𝙣𝙩𝙞𝙨𝙩𝙨 𝙛𝙧𝙤𝙢 𝙩𝙝𝙚 𝙐𝙣𝙞𝙫𝙚𝙧𝙨𝙞𝙩𝙮 𝙤𝙛 𝘽𝙞𝙧𝙢𝙞𝙣𝙜𝙝𝙖𝙢 𝙝𝙖𝙫𝙚 𝙨𝙝𝙤𝙬𝙣 𝙩𝙝𝙖𝙩 𝙖 𝙗𝙧𝙖𝙞𝙣-𝙥𝙚𝙣𝙚𝙩𝙧𝙖𝙩𝙞𝙣𝙜 𝙘𝙖𝙣…
Researchers from Santa Clara University, New Jersey Institute of Technology and the University of Hong Kong have been able to successfully teach microrobots how to swim via deep reinforcement learning, marking a substantial leap in the progression of microswimming capability.
There has been tremendous interest in developing artificial microswimmers that can navigate the world similarly to naturally-occuring swimming microorganisms, like bacteria. Such microswimmers provide promise for a vast array of future biomedical applications, such as targeted drug delivery and microsurgery. Yet, most artificial microswimmers to date can only perform relatively simple maneuvers with fixed locomotory gaits.
The artificial intelligence-powered swimmer switches between different modes of locomotory gaits (color-coded) autonomously in tracing a complex trajectory ‘SWIM’. (Image: Commun. Phys., 5,158 (2022))
New York’s Gorbunova Aging Research Center team is encouraged by frailty results from SIRT6 activator trial.
SIRT6, the so-called “longevity sirtuin” has been making rather a name for itself.
SIRT6 is a protein with an important job. It is vital for both normal base excision repair and double-strand break repair of DNA damage – damage that can lead to genomic instability, which ultimately contributing to aging. These repairs decline with age but can be boosted with SIRT6 [1].
Continue reading “Longevity sirtuin clinical trial teases promising results” »
MPXV was first discovered during a nonfatal outbreak at an animal facility in Copenhagen, Denmark, in 1958. The facility received a continual supply of Asian monkeys (mostly M. fascicularis) and rhesus macaques (Macaca mulatta), which were used for polio vaccine research. The first outbreak occurred 2 months after the monkeys had been received and the second outbreak occurred 4 months after the initial outbreak. The outbreaks occurred in M. fascicularis that had arrived from Singapore. Upon arrival, monkeys were treated with antibiotics and appeared in satisfactory health.
Monkeypox virus (MPXV) was discovered in 1958 during an outbreak in an animal facility in Copenhagen, Denmark. Since its discovery, MPXV has revealed a propensity to infect and induce disease in a large number of animals within the mammalia class from pan-geographical locations. This finding has impeded the elucidation of the natural host, although the strongest candidates are African squirrels and/or other rodents. Experimentally, MPXV can infect animals via a variety of multiple different inoculation routes; however, the natural route of transmission is unknown and is likely to be somewhat species specific. In this review we have attempted to compile and discuss all published articles that describe experimental or natural infections with MPXV, dating from the initial discovery of the virus through to the year 2012. We further discuss the comparative disease courses and pathologies of the host species.
Keywords: aerosol, animals, infection, intrabronchial, intradermal, intramuscular, intranasal, intratracheal, intravenous, outbreak, primates, subcutaneous.
As most of you know I have cancer called multiple myeloma and have had it for almost a decade now. Unfortunately medical bills are staggering, especially in the US. I am asking to reach a goal of $10,000 to help wipe out if not most of my medical debt and expenses. I have over 1,000 friends on Facebook. If each friend donated $8.00 this would help me not only reach but exceed my goal. Please consider helping:
If anyone needs proof of my diagnosis or medical debt please message me.
I have outlined my journey with cancer several years ago on Lifeboat Foundation’s blog: https://lifeboat.com/blog/2018/09/83169
Continue reading “Cancer Bills, organized by Nicholas Avery” »
Circa 2018
New research has opened doors to using the gene-editing tool CRISPR to stop cancer cells from dividing indefinitely.
Scientists warn that the findings aren’t yet clinically relevant but say the research raises ethical questions about the definition of death.
They claimed that artificial intelligence can actually solve some of the hardest challenges that affect the delivery of dementia treatment to old people, especially those with Alzheimer’s disease.
In 2021, the National Library of Medicine revealed that more than 6.2 million U.S. residents are suffering from Alzheimer’s.
Researchers from TU Delft have constructed the smallest flow-driven motors in the world. Inspired by iconic Dutch windmills and biological motor proteins, they created a self-configuring flow-driven rotor from DNA that converts energy from an electrical or salt gradient into useful mechanical work. The results open new perspectives for engineering active robotics at the nanoscale.
The article is now published in Nature Physics (“Sustained unidirectional rotation of a self-organized DNA rotor on a nanopore”).
Rotary motors have been the powerhouses of human societies for millennia: from the windmills and waterwheels across the Netherlands and the world to today’s most advanced off-shore wind turbines that drive our green-energy future.
