Lifeboat Foundation

Using non-invasive techniques to manipulate our emotions, it might be possible to curtail the screaming horrors that plague our sleep.

A study last year conducted on 36 patients diagnosed with a nightmare disorder showed that a combination of two simple therapies reduced the frequency of their bad dreams.

Scientists invited the volunteers to rewrite their most frequent nightmares in a positive light and then played sound associated with positive experiences as they slept.

Researchers at the University of Toronto have developed an artificial intelligence system that can create proteins not found in nature using generative diffusion, the same technology behind popular image-creation platforms such as DALL-E and Midjourney.

The system will help advance the field of generative biology, which promises to speed drug development by making the design and testing of entirely new therapeutic proteins more efficient and flexible.

“Our model learns from image representations to generate fully new proteins, at a very high rate,” says Philip M. Kim, a professor in the Donnelly Centre for Cellular and Biomolecular Research at U of T’s Temerty Faculty of Medicine. “All our proteins appear to be biophysically real, meaning they fold into configurations that enable them to carry out specific functions within cells.”

The WHO says covid is no longer an emergency, yet does not say where covid originated from. No one knows. What I know is that covid is a cute name for SARS/Coronavirus. Something made in a lab at UNC Chapel Hill with Ralph Baric and his collegue from Wuhan China which he shared his gain of function research with. However the Nature article published in 2015 has this disclaimer, yet there is no animal origin after more than 3 years. So what do we believe?

“30 March 2020 Editors’ note, March 2020: We are aware that this article is being used as the basis for unverified theories that the novel coronavirus causing COVID-19 was engineered. There is no evidence that this is true; scientists believe that an animal is the most likely source of the coronavirus.”

The results indicate that group 2b viruses encoding the SHC014 spike in a wild-type backbone can efficiently use multiple orthologs of the SARS receptor human angiotensin converting enzyme II (ACE2), replicate efficiently in primary human airway cells and achieve in vitro titers equivalent to epidemic strains of SARS-CoV. ACE2 🤔

Continue reading “A SARS-like cluster of circulating bat coronaviruses shows potential for human emergence Medicine” »

Will new molecular bioprinting technologies soon allow us to print our DNA?

Other research points to a future when we will be able to print DNA, nucleotide by nucleotide.

Servers running software sold by Salesforce are leaking sensitive data managed by government agencies, banks, and other organizations, according to a post published Friday by KrebsOnSecurity.

At least five separate sites run by the state of Vermont permitted access to sensitive data to anyone, Brian Krebs reported. The state’s Pandemic Unemployment Assistance program was among those affected. It exposed applicants’ full names, Social Security numbers, addresses, phone numbers, email addresses, and bank account numbers. Like the other organizations providing public access to private data, Vermont used Salesforce Community, a cloud-based software product designed to make it easy for organizations to quickly create websites.

Another affected Salesforce customer was Columbus, Ohio-based Huntington Bank. It recently acquired TCF Bank, which used Salesforce Community to process commercial loans. Data fields exposed included names, addresses, Social Security numbers, titles, federal IDs, IP addresses, average monthly payrolls, and loan amounts.

An artificial intelligence system enables robots to conduct autonomous scientific experiments—as many as 10,000 per day—potentially driving a drastic leap forward in the pace of discovery in areas from medicine to agriculture to environmental science.

Reported today in Nature Microbiology, the research was led by a professor now at the University of Michigan.

Continue reading “AI could run a million microbial experiments per year, says study” »

Scientists used a new, noninvasive method to successfully isolate DNA found on the prehistoric artifact.

An international team of researchers led by the Netherlands Cancer Institute developed a method to better predict the outgrowth of ductal carcinoma in situ (DCIS), a possible precursor of breast cancer, into invasive breast cancer. Using mice into which cells from women with DCIS were inserted, researchers can better identify which DCIS patients are at risk for breast cancer.

The study was published in Cancer Cell and is part of PRECISION, a major international research project on DCIS.

DCIS consists of aberrant cells in the milk ducts of the breast. In the Netherlands, it is found in about 2,300 women a year, about 80% of them detected at breast cancer screening. This is because calcium splashes can be seen on the X-ray of the breast (the mammogram), which may indicate DCIS.

Next week will see the first Sheba Longevity Conference, a meeting that will bring together all relevant stakeholders in the multidisciplinary field of longevity medicine, providing a forum for showcasing outstanding research and scientific breakthroughs. The conference will also include the opening ceremony of the public academic hospital longevity center at Sheba Hospital.

The conference aims to foster collaborations that will accelerate the translation of scientific discoveries into clinical practices and facilitate a shift in Israel’s national healthy longevity policy. The event will also include an exhibition space for sponsors, partners and industry representatives to promote dialogue and showcase their work.

Continue reading “New longevity conference will span research to evidence-based clinical practice” »