Lifeboat Foundation

Aging. We all face it. Nobody’s immune and we’ve long tried to reverse it, stop it or just even slow it down. While advances have been made, true age-reversal at a cellular level remains difficult to achieve. By taking a different approach, however, researchers at Houston Methodist made a surprising discovery leading to the development of technology with the ability to rejuvenate human cells. And that couldn’t be more important for the small population of children who are aging too quickly — children with progeria.

John P. Cooke, M.D., Ph.D., department chair of cardiovascular sciences at Houston Methodist Research Institute, and his colleagues, describe their findings in a Research Letter titled “Telomerase mRNA Reverses Senescence in Progeria Cells,” appearing online July 31 and in print Aug. 8 in the Journal of the American College of Cardiology, a leading medical journal in the field of cardiovascular disease.

Cooke studied cells from children with progeria, a rare condition marked by rapid aging that usually robs them of the chance to live beyond their early teens. They focused on progeria, because the condition tells them a lot about aging in general that’s ultimately relevant to all of us.

Continue reading “Researchers develop technology to make aged cells younger” »

It’s one thing to be wowed by Amazon’s Alexa and her ability to turn off Katy Perry, or turn on the lights. But what if the voice-activated artificial intelligence could help control a robotic device designed to help people walk?

That’s the hope of Bionik Laboratories, which announced Tuesday that it has integrated Alexa into its ARKE lower body exoskeleton. The product is in clinical development, and the future goal is for individuals who have suffered a spinal cord injury or are otherwise severely impaired in their lower body to gain mobility such as standing and walking.

Cellular senescence is widely considered by academia to be one of the causes of aging and one that leads to a number of age-related diseases. There has been a high level of interest in recent years in cellular senescence and approaches that seek to remove senescent cells as a route to delaying or even preventing age-related diseases.

Today we have a new study where researchers focus on pulmonary fibrosis and the role of cellular senescence.

Dr. Oliver Medvedik, Dr. Aubrey de Grey, and Dr. Alexandra Stolzing discuss.

News from Veritas and remember Veritas are offering a whole genome sequence as one of the rewards in our AgeMeter campaign at Lifespan.io:

https://www.lifespan.io/campaigns/agemeter-biomarker-scan/#reward_12

“On August 3, sequencing company Veritas Genetics bought one of the most influential: seven-year old Curoverse. Veritas thinks AI will help interpret the genetic risk of certain diseases and scour the ever-growing databases of genomic, medical, and scientific research.”

Continue reading “Veritas Genetics Scoops Up an AI Company to Sort Out Its DNA” »

As one of the most visible 2016 presidential candidates—and now as a leading 2018 contender for Governor in California—Zoltan Istvan has been the “Science Candidate,” traveling around America to discuss the issues of transhumanism and radical longevity that are transforming humanity. Soon the issues of AI, genetic editing, designer babies, bionic organs, automation, and neural prosthetics will challenge and dominate political discourse. America must embrace radical science with bold polices.

The study of consciousness and what makes us individuals is a topic filled with complexities. From a neuroscience perspective, consciousness is derived from a self-model as a unitary structure that shapes our perceptions, decisions and feelings. There is a tendency to jump to the conclusion with this model that mankind is being defined as self-absorbed and only being in it for ourselves in this life. Although that may be partially true, this definition of consciousness doesn’t necessarily address the role of morals and how that is shaped into our being. In the latest addition to The Galactic Public Archives, Dr. Ken Hayworth tackles the philosophical impact that technologies have on our lives.

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Dr. Alexandra Stolzing and Dr. Aubrey de Grey discuss.

Jennifer Doudna reflects on what she sees as achievements and misuses of CRISPR genetic editing method.