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Miniaturized semiconductor devices with energy harvesting features have paved the way to wearable technologies and sensors. Although thermoelectric systems have attractive features in this context, the ability to maintain large temperature differences across device terminals remains increasingly difficult to achieve with accelerated trends in device miniaturization. As a result, a group of scientists in applied sciences and engineering has developed and demonstrated a proposal on an architectural solution to the problem in which engineered thin-film active materials are integrated into flexible three-dimensional (3D) forms.

The approach enabled efficient thermal impedance matching, and multiplied heat flow through the harvester to increase efficient power conversion. In the study conducted by Kewang Nan and colleagues, interconnected arrays of 3D thermoelectric coils were built with microscale ribbons of the active material monocrystalline silicon to demonstrate the proposed concepts. Quantitative measurements and simulations were conducted thereafter to establish the basic operating principles and key design features of the strategy. The results, now published on Science Advances, suggested a scalable strategy to deploy hard thermoelectric thin-films within energy harvesters that can efficiently integrate with soft material systems including human tissue to develop wearable sensors in the future.

Thermoelectric devices provide a platform to incorporate ubiquitous thermal gradients that generate electrical power. To operate wearable sensors or the “Internet of Things” devices, the temperature gradient between the surrounding environment and the human body/inanimate objects should provide small-scale power supplies. Continued advances in the field focus on aggressive downscaling of power requirements for miniaturized systems to enhance their potential in thermoelectric and energy harvesting applications. Integrated processors and radio transmitters for example can operate with power in the range of subnanowatts, some recent examples are driven via ambient light-based energy harvesting and endocochlear potential. Such platforms can be paired with sensors with similar power to enable distributed, continuous and remote environmental/biochemical monitoring.

Continue reading “Stretchable thermoelectric coils for energy harvesting in miniature flexible wearable devices” »

MORGANTOWN — World-leading brain experts at West Virginia University’s Rockefeller Neuroscience Institute are celebrating the historic breakthrough Alzheimer patients around the global have been waiting for.

“For Alzheimer’s, there’s not that many treatments available despite hundreds of clinical trials over the past two decades and billions of dollars spent,” said Dr. Ali Rezai, a neurosurgeon at WVU who led the team of investigators that successfully performed a phase II trial using focused ultrasound to treat a patient with early stage Alzheimer’s.

The WVU team tested the innovative treatment in collaboration with INSIGHTEC, an Israeli medical technology company. Earlier this year, INSIGHTEC was approved by the U.S. Food and Drug Administration to begin a phase II clinical trial of the procedure and selected the WVU Rockefeller Neuroscience Institute as the first site in the United States for the trial.

Continue reading “Historic breakthrough: WVU Rockefeller Neuroscience team first to use ultrasound to treat Alzheimer’s” »

Inspired by success with T cells, scientists equip other immune cells with cancer-homing protein.

Scientists are now closer than ever to being able to use graphene as a superconductor – to conduct electricity with zero resistance – making it useful for developing energy efficient gadgets, improving medical research, upgrading power grids, and much more besides.

The key to the new approach is heating a silicon carbide (SiC) crystal, itself a superconductor, until the silicon atoms have all evaporated. This leaves two graphene layers on top of each other in a way that, in certain conditions, offers no resistance to electrical current.

A similar dual-layer approach was also successfully used to turn graphene into a superconductor earlier this year. The difference here is the layers don’t have to be carefully angled on top of each other, which should make it easier to reproduce at scale.

Continue reading “We Just Got Closer Than Ever to Unlocking Graphene’s Superconducting Powers” »

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New research is zeroing in on a biochemical basis for the placebo effect — possibly opening a Pandora’s box for Western medicine.

Credit Credit Photo illustration by Paul Sahre.

Continue reading “What if the Placebo Effect Isn’t a Trick?” »

With the Ebola outbreak in the Democratic Republic of Congo continuing to spread, neighboring Uganda deploys its health care defenses.

An extraordinary new film about identical triplets throws doubt on the dominance of DNA.

Motivation is such an intangible aspect of the human spirit that we often forget it has very real, neurochemical origins. We admire it in others and strive for it in ourselves (see: every Nike ad ever made), and now we are getting closer to potentially inducing that motivational feeling with drugs.

John Salamone, Ph.D., a professor at the University of Connecticut with a background in neural and behavioral pharmacology, has been working with the drug company Chronos Therapeutics to develop a drug that can restore motivation in people who have lost it — whether that’s due to the symptoms of depression, struggle with disease, or otherwise. He unveiled his early results on rats this week in a presentation at the Society For Neuroscience’s conference in San Diego, where he tells Inverse his board was bustling with activity:

“Basically we stood there for four hours and were busy the entire time,” says Salamone. The reception was overwhelmingly positive, he adds. “We didn’t have anyone say ‘This is crazy! This will never work!’”.

Continue reading “Potent, Cocaine-Like Motivational Drug Unveiled at Neuroscience Conference” »