Lifeboat Foundation

Rejuvenate Bio’s treatment is a gene therapy that dials up expression of the genes sTGFbetaR2 and FGF21 to reduce levels of the cytokine TGF-beta1 and boost levels of the hormone FGF21, respectively. Both genes are associated with longevity.

“What we have seen from using a combination of two genes is the ability to affect multiple age-related diseases at once,” Oliver said.

Rejuvenate Bio published data in November 2019 showing that targeting these two genes in mice reduced kidney atrophy and reversed weight gain and Type 2 diabetes. The company had given extra copies of those genes, alone and in combination with each other and another gene called alpha-Klotho to see if they could boost the mice’s health and life spans. It found out that more isn’t necessarily better, as mice that were given all three genes together fared worse than the other animals did.

Someday, scientists believe, tiny DNA-based robots and other nanodevices will deliver medicine inside our bodies, detect the presence of deadly pathogens, and help manufacture increasingly smaller electronics.

Researchers took a big step toward that future by developing a new tool that can design much more complex DNA robots and nanodevices than were ever possible before in a fraction of the time.

Continue reading “MagicDNA: Tiny, Complex DNA Robots Designed in Minutes Instead of Days” »

If you want to own a piece of a longevity technology company, here is your chance.

Invest as little as $100 in startups and small businesses. Wefunder is the largest Regulation Crowdfunding portal.

The Art Of Human Care For Covid-19 — Dr. Hassan A. Tetteh MD, Health Mission Chief, U.S. Department of Defense (DoD), Joint Artificial Intelligence Center, The Pentagon.

Dr. Hassan A. Tetteh, MD, is the Health Mission Chief, at the Department of Defense (DoD) Joint Artificial Intelligence Center, serving to advance the objectives of the DoD AI Strategy, and improve war fighter healthcare and readiness with artificial intelligence implementations.

Continue reading “Dr. Hassan Tetteh, MD — Health Mission Chief — DoD/JAIC — The Art of Human Care For COVID-19” »

The number of confirmed cases of the coronavirus-borne illness COVID-19 climbed above 142 million on Tuesday, and India remained a hot spot, recording more than 250000 new infections and over 1700 deaths in the past 24 hours alone.

India has the second-highest case tally in the world after the U.S. with more than 15 million cases, according to data aggregated by Johns Hopkins University. The country of more than 1.3 billion has suffered more than 180000 deaths — and experts say these numbers are likely an undercount, the Associated Press reported.

The capital New Delhi entered lockdown again on Monday in an effort to curb a surge in cases that has hospitals overflowing, intensive-care units full and oxygen in short supply.

Circa 2020

Robots and stranger machines have been using a particular band of ultraviolet light to sterilize surfaces that might be contaminated with coronavirus. Those that must decontaminate large spaces, such as hospital rooms or aircraft cabins, use large, power-hungry mercury lamps to produce ultraviolet-C light. Companies around the world are working to improve the abilities of UV-C producing LEDs, to offer a more compact and efficient alternative. Earlier this month, Seoul Viosys showed what it says is the first 99.9 percent sterilization of SARS-COV-2, the coronavirus that causes COVID-19, using ultraviolet LEDs.

UV LEDs are deadly to viruses and bacteria, because the 100–280 nanometer wavelength C-band shreds genetic material. Unfortunately, it’s also strongly absorbed by nitrogen in the air, so sources have to be powerful to have an effect at a distance. (Air is such a strong barrier, that the sun’s UV-C doesn’t reach the Earth’s surface.) Working with researchers at Korea University, in Seoul, the company showed that its Violed LED modules could eliminate 99.9 percent of the SARS-COV-2 virus using a 30-second dose from a distance of three centimeters.

Continue reading “Ultraviolet-LED Maker Demonstrates 30-Second Coronavirus Kill” »

The dirt scattered across the floor of an ancient, remote cave in Mexico has yielded a new source of viable ancient DNA.

For the first time, scientists have sequenced ancient DNA from soil samples — and it’s all thanks to the Upper Paleolithic bears that prolifically used the cave as their toilet around 16000 years ago.

The scientists describe their work as “the Moon landing of genomics”, as the breakthrough means fossilized remains are no longer the only way of obtaining ancient DNA. Further, it shows ancient DNA can now be studied in the context of populations, rather than scattered, fragmentary individuals.

Cancer and other diseases have another means of travel.

The continuous network of fluid-filled compartments crosses organ barriers and might serve as a conduit for tumor cells to spread.

The mRNA technology at the heart of two Covid-19 shots has been decades in the making. Now it may soon be used to fight cancer and HIV.

#Prognosis #Vaccine #BloombergQuicktake.

Continue reading “How Covid Vaccine Tech Could Fight Cancer Soon” »