Lifeboat Foundation

Viruses are masterful invaders. They cannibalize host cells by injecting their genetic material, often making thousands of copies of themselves in a single cell to ensure their replication and survival.

Some RNA viruses insert their genetic material as a single piece, while others chop it up into pieces. The latter are aptly named segmented viruses.

Such segmented RNA viruses—including several that cause human diseases like influenza—have been a longstanding enigma to researchers: How do they accomplish the precise copying and insertion of each segment? How do they ensure that individual segments are all copied by the same enzyme while ensuring that each segment can make different amounts of RNA? Such exquisite regulation is critical to make the correct levels of the viral proteins necessary for successful replication.

Continue reading “Study uncovers key mechanism that allows some of the world’s deadliest viruses to replicate” »

Huge plastic waste dumps float in the Oceans bigger than continents. Some 10% of world’s plastic waste finds its way into the sea and ends up in the central regions where slow moving circular currents trap debris into one large constantly moving mass of plastic. This is slowly being broken down into a plastic dust that marine wildlife mistake for food. Small fish consume tiny bits of plastic as if they were normal plankton. Those fish are then consumed by larger species and the plastic contamination moves up the food chain. Over a million seabirds, as well as more than 100 thousand marine mammals, die every year from ingesting plastic debris. Some researchers estimate that there are over six kilos of plastic for every kilo of naturally occurring plankton in the Pacific plastic waste dump.

Dead seabirds having mistaken plastics for food, have been found with discarded plastic lighters, water bottle caps and scraps of plastic bags in their stomachs. / Oceanic gyres: the circular movement of the ocean waters concentrates the plastic in the centre of the oceans.

But maybe things are not as bad as it looks: scientists working on the pollution saw that it did not grow in 22 years, even if the plastic production grew fourfold. An organism may be eating plastic in the ocean, but whether the bug is green or mean remains to be seen.

Continue reading “Plastic eating bacteria in the oceans” »

The billionaire owner of Blue Origin outlines plans for mining, manufacturing, and colonies in space.

[Photo: Flickr user NASA Goddard Space Flight CenterFollow;courtesy of BlueOrigin].

Scenes from inside the Arctic Circle show a rapidly growing military presence.

Scientists might have found an early detection method for some forms of dementia, according to new research by the University of Arizona and the University of Toronto’s Baycrest Health Sciences Centre.

According to the study published in the journal Neuropsychologia last month, patients with a rare neurodegenerative brain disorder called Primary Progressive Aphasia, or PPA, show abnormalities in brain function in areas that look structurally normal on an MRI scan.

“We wanted to study how degeneration affects function of the brain,” said Aneta Kielar, the study’s lead author and assistant professor in the UA Department of Speech, Language and Hearing Sciences.

Continue reading “Detecting dementia’s damaging effects before it’s too late” »

Planes, Drones, and AI Machines

But going from Mach 2 to Mach 5 is not an easy undertaking. Hermeus is hoping to pull from existing technologies to make its insanely fast passenger plane a reality, including titanium materials and cutting edge rocketry.

It’s impossible to tell what the future of air travel will look like. If supersonic airplanes aren’t it, SpaceX founder Elon Musk has pushed for the idea that we’ll go between Earthly destinations in rockets that can technically take us to Mars.

Continue reading “Blazing Supersonic Plane Could Zoom From NY to Paris in 90 Min” »

Circa 2018

Lockheed Martin has won a nearly quarter-billion dollar NASA contract to develop a plane capable of supersonic speed without creating the deafening sonic boom that comes with breaking the sound barrier.

The cost-plus NASA contract, valued at $247.5 million, will allow the defense contractor’s secretive Skunk Works division to continue development of Lockheed Martin’s Quiet Supersonic Technology (or QueSST) aircraft. This is “NASA’s first X-plane in a generation,” a Lockheed Martin spokesperson told CNBC on Tuesday.

Continue reading “NASA hands massive supersonic contract to Lockheed Martin, with one catch: No sonic boom” »

It’s very easy to forget that complex life on Earth almost missed the boat entirely. As the Sun’s luminosity gradually increases, the oceans will boil away, and the planet will no longer be in the habitable zone for life as we know it. Okay, we likely have a billion years before this happens—by which point our species will probably have destroyed itself or moved away from Earth—but Earth itself is 4.5 billion years old or so, and eukaryotic life only started to diversify 800 million or so years ago, at the end of the “boring billion.”

In other words, life seems to have arisen around four billion years ago, shortly after Earth formed, but then a few billion years passed before anything complex evolved. Another few hundred million years of bacteria, algae, and microbes sliding around in the anoxic sludge of the boring billion, and intelligent life might never have evolved at all.

Unraveling the geologic mysteries of the boring billion, and why it ended when it did, is a complex scientific question. Different parts of the earth system, including plate tectonics, the atmosphere, and the biosphere of simple lichens and cyanobacteria interacted to eventually produce the conditions for life to diversify, flourish, and grow more complex. But it is generally accepted that simple cyanobacteria (single-celled organisms that can produce oxygen through photosynthesis) were key players in providing Earth’s atmosphere and oceans with oxygen, which then allowed complex life to flourish.

Continue reading “How Cyanobacteria Could Help Save the Planet” »

Chikungunya virus, once confined to the Eastern Hemisphere, has infected more than 1 million people in the Americas since 2013, when mosquitoes carrying the virus were discovered in the Caribbean. Most people who become infected develop fever and joint pain that last about a week. But in up to half of patients, the virus can cause severe arthritis that persists for months or years. There is no treatment to prevent the short-lived infection from persisting into chronic arthritis.

Now, researchers have uncovered information that could help stop the debilitating condition. A team at Washington University School of Medicine in St. Louis has snapped high-resolution pictures of the virus latched onto a protein found on the surface of cells in the joints. The protein used in the study was taken from mice, but people have the same protein, and the virus interacts with the mouse and human proteins in virtually identical ways.

The structures, published May 9 in the journal Cell, shows in atomic-level detail how the virus and cell-surface protein fit together – data that promises to accelerate efforts to design drugs and vaccines to prevent or treat arthritis caused by chikungunya or related viruses.

Continue reading “Snapshot of chikungunya could lead to drugs, vaccines for viral arthritis” »