Could an exotic super heavy element provide the key to humanity’s future in the stars? According to physicist Bob Lazar, “Element 115” is the fuel source for an alien spacecraft he was hired to reverse-engineer by the U.S. government—and if we can harness its awesome power, it will change our world forever.
Harvard and Japanese scientists say they’ve made a “landmark” discovery in cancer drug development. In a new study published Monday, they say they have finally found a way to synthesize in bulk a complex class of promising cancer-fighting molecules derived from sea sponges. Their new strategy has already helped speed up research into these molecules, including a planned clinical trial in humans.
Called halichondrins, the molecules were originally discovered by Japanese researchers in the mid-1980s in sea sponges. It became quickly apparent that they were capable of aggressively fighting tumors in both mice and lab dishes containing human cells, and in a way different from other existing treatments.
Toyota is working on potentially game-changing solid-state batteries, and they may arrive sooner than expected. The Japanese automaker’s R&D boss said Toyota hopes to unveil the batteries in 2020, two years ahead of schedule. Toyota plans to introduce more electric cars to its lineup.
A prototype solid-state battery based on lithium and glass faces criticism over claims that its capacity increases over time.
Tam Hunt interviews Prof. Morgan Levine about her work with epigenetics and aging.
One of the biggest breakthroughs in biology in the last few decades has been the discovery of epigenetics. Rather than changing the genes themselves, epigenetics change how genes are expressed, allowing our cells to differentiate between their various types.
However, the epigenetics of our cells change over time. There is some debate over how much epigenetic alterations are a cause or a consequence of other age-related damage, but they are one of the primary hallmarks of aging.
To understand our brains, scientists need to know their components. This theme underlies a growing effort in neuroscience to define the different building blocks of the brain—its cells.
With the mouse’s 80 million neurons and our 86 billion, sorting through those delicate, microscopic building blocks is no small feat. A new study from the Allen Institute for Brain Science, which was published today in the journal Nature Neuroscience, describes a large profile of mouse neuron types based on two important characteristics of the cells: their 3D shape and their electrical behavior.
The study, which yielded the largest dataset of its kind from the adult laboratory mouse to date, is part of a larger effort at the Allen Institute to discover the brain’s “periodic table” through large-scale explorations of brain cell types. The researchers hope a better understanding of cell types in a healthy mammalian brain will lay the foundation for uncovering the cell types that underlie human brain disorders and diseases.
Geneticists exploring the dark heart of the human genome have discovered big chunks of Neanderthal and other ancient DNA. The results open new ways to study both how chromosomes behave during cell division and how they have changed during human evolution.
Centromeres sit in the middle of chromosomes, the pinched-in “waist” in the image of a chromosome from a biology textbook. The centromere anchors the fibers that pull chromosomes apart when cells divide, which means they are really important for understanding what happens when cell division goes wrong, leading to cancer or genetic defects.
But the DNA of centromeres contains lots of repeating sequences, and scientists have been unable to properly map this region.
In quantum electrodynamics, the choice of gauge (i.e. specific mathematical formalism used to regulate degrees of freedom) can greatly influence the form of light-matter interactions. Interestingly, however, the “gauge invariance” principle implies that all physical results should be independent from a researcher’s choice of gauge. The quantum Rabi model, which is often used to describe light-matter interactions in cavity-QED, has been found to violate this principle in the presence of ultrastrong light-matter coupling, and past studies have attributed this failure to the finite-level truncation of the matter system.
A team of researchers at RIKEN (Japan), Università di Messina (Italy) and the University of Michigan (U.S.) have recently carried out a study investigating this topic further. In their paper, published in Nature Physics, they identified the source of this gauge violation and provided a method to derive light-matter Hamiltonians in truncated Hilbert spaces, which can produce gauge-invariant physical results even in extreme light-matter interaction regimes.
“Ultrastrong coupling between light and matter has, in the past decade, transitioned from a theoretical idea to an experimental reality,” Salvatore Savasta, one of the researchers who carried out the study, told Phys.org. “It is a new regime of quantum light-matter interaction, which goes beyond weak and strong coupling to make the coupling strength comparable to the transition frequencies in the system. These regimes, besides enabling intriguing new physical effects, as well as many potential applications, represents an opportunity to deepen our understanding subtle aspects of the interaction of light and matter.”
