Lifeboat Foundation

Researchers from the Beijing Institute of Brain Disorders have discovered a new method of using exosomes to deliver aptamers that prevent the accumulation of α-synuclein aggregates, which are the cause of Parkinson’s disease [1].

α-Synuclein Aggregates

Like Alzheimer’s, Parkinson’s disease is characterized by protein aggregation caused by a loss of proteostasis, one of the hallmarks of aging. In order for the brain to function properly, non-aggregated α-synuclein proteins are needed in order to facilitate the release of dopamine, a neurotransmitter, in nerve cell synapses. α-synuclein only becomes a problem when proteostasis fails and the proteins misfold, aggregate, and accumulate.

Most soft robots are controlled manually or pre-programmed but the lenses mimic the natural electric signals in the human eyeball that are active even when the eye itself is closed.

Mechanical engineers have discovered a way to produce more electricity from heat than thought possible by creating a silicon chip, also known as a ‘device,’ that converts more thermal radiation into electricity. This could lead to devices such as laptop computers and cellphones with much longer battery life and solar panels that are much more efficient at converting radiant heat to energy.

Julio Gil-Pulgar · @gil_pulgar | Jul 29, 2019 | 06:00.

Blockchain

We look back at the historic 1969 moon landing of the Apollo 11. Hear stories from the original crew, explore photos and experience the launch in VR.

The asteroid managed to get within just 73,000 kilometers of our planet without anyone noticing. The miss lends a new sense of urgency to preparations for a potential collision one day.

The news: On Thursday July 25 an asteroid dubbed “Asteroid 2019 OK”, measuring 57 to 130 meters wide (187 to 427 feet), got uncomfortably close to Earth, according to NASA’s near-Earth objects database. It was less than one-fifth of the distance to the moon away, making it a very close call in space terms. If it had landed on a populated area it could have caused major damage, although this outcome is statistically quite unlikely.

Should we worry? It’s hard not to feel concerned that a “city-killer” sized asteroid wasn’t detected further ahead of time. It was announced just hours before it passed by Earth, after being detected just a few days beforehand by teams in the US and Brazil. Its relatively small size, unusual orbit, and fast speed all conspired to make it tough to spot, researchers told the Washington Post.

But getting human cells to grow in another species is not easy. Nakauchi and colleagues announced at the 2018 American Association for the Advancement of Science meeting in Austin, Texas that they had put human iPS cells into sheep embryos that had been engineered not to produce a pancreas. But the hybrid embryos, grown for 28 days, contained very few human cells, and nothing resembling organs. This is probably because of the genetic distance between humans and sheep, says Nakauchi.

The research could eventually lead to new sources of organs for transplant, but ethical and technical hurdles need to be overcome.

For decades, computer programmers have been trying to beat multiplayer games by finding reliable patterns in data.

Researchers at Facebook and Carnegie Mellon University published a whitepaper in Science Journal in July that flips this switch. Their software embraces randomness, and it is reliably beating humans at games.

Jump to media player The semi-autonomous robot is able to use human tools and guide itself across difficult terrain.