Lifeboat Foundation

A research group at ETH Zurich, Switzerland, has made it possible to edit hundreds of genes at once with CRISPR gene editing.

CRISPR gene editing has revolutionized the biotech industry by providing an easy and quick way to genetically modify organisms. So far, however, CRISPR techniques have only managed to edit a maximum of seven genes at once. This limits the potential of the technique in creating cell therapies, since whole networks of genes need to be reprogrammed to control each cell’s fate.

The Swiss research group devised a way to overcome this limitation with a CRISPR technique able to edit 25 genes in one go. This number could also be increased to up to hundreds of genes at a time. This method therefore makes it possible to edit gene networks, and reprogram stem cells to become cell therapies such as skin cells or insulin-producing pancreatic cells.

Bago pa pirmahan ni Pangulong Rodrigo Duterte ang batas na bubuo sa isang national space agency, may Pinoy microsatellites nang lumilipad sa outer space. Ano kaya ang ginagawa nila sa kalawakan? Naghahanap ng aliens, black holes, o bagong planeta? Ipakikilala sa atin ni Hillary Andales sina Diwata 1 at Diwata 2, ang kauna-unahang Pinoy microsatellites.

The de Grey… AEWR.

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CUTTING ROOM Scientists will soon wield the molecular scissors CRISPR/Cas9 in the human body. Some people with a form of inherited blindness will have the gene editor injected into their eyes, where researchers hope it will snip out a mutation.

BIG GULP Gravitational waves may have revealed a black hole in the process of swallowing up a neutron star (illustrated). If confirmed, the event would be the first of its kind ever seen.

SUPERNOVA SNOWFALL Scientists have found a fingerprint of exploding stars, or supernovas, in Antarctic snow that fell within the last 20 years. Here, part of a supernova remnant, Vela, is shown.

Most people who’ve been jabbed by a needle know the drill: First the pierce, then the sharp, searing pain and an urge to pull away, or at least wince. While the exact circuitry behind this nearly universal reaction is not fully understood, scientists may have just found an important piece of the puzzle: a previously unknown sensory organ inside the skin.

Dubbed the nociceptive glio-neural complex, this structure is not quite like the typical picture of a complex organ like the heart or the spleen. Instead, it’s a simple organ made up of a network of cells called glial cells, which are already known to surround and support the body’s nerve cells. In this case, the glial cells form a mesh-like structure between the skin’s outer and inner layers, with filament-like protrusions that extend into the skin’s outer layer. (Also find out about a type of simple organ recently found in humans, called the interstitium.)

As the study team reports today in the journal Science, this humble organ seems to play a key role in the perception of mechanical pain—discomfort caused by pressure, pricking, and other impacts to the skin. Until now, individual cells called nociceptive fibers were thought to be the main starting points for this kind of pain.

https://www.youtube.com/watch?v=TJrf8K_myAw

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In the past few videos in this series, we have delved quite deep into the field of machine learning, discussing both supervised and unsupervised learning.

Continue reading “The Dawn of AI (Machine Learning Tribes | Deep Learning | What Is Machine Learning)” »