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Mar 31, 2020

Getting Closer to a Blood Test for Alzheimer’s Disease?

Posted by in categories: biotech/medical, neuroscience

As research on Alzheimer’s disease (AD) advances, a desperate need remains for an easy blood test to help diagnose the condition as early as possible. Ideally, such a test could also distinguish AD from other forms of dementia that produce similar symptoms. As published recently in Nature Medicine, an NIH-funded research team has designed a simple blood test that is on course to meet these criteria [1].

The latest work builds on a large body of work showing that one secret to predicting a person’s cognitive decline and treatment response in AD lies in a protein called tau. Using the powerful, but expensive, approach of PET scan imaging, we know that tau builds up in the brain as Alzheimer’s disease progresses. We also know that some tau spills from the brain into the bloodstream.

The trouble is that the circulating tau protein breaks down far too quickly for a blood test to offer a reliable measure of what’s happening in a person’s brain. A few years ago, researchers discovered a possible solution: test for blood levels of a slightly different and more stable version of the protein called pTau181 [2]. (The “p” in its name comes from the addition of phosphorus in a particular part of the protein’s structure.)

Mar 31, 2020

Maker Mask launches in Seattle using 3D-printing technology to produce protective gear

Posted by in categories: 3D printing, biotech/medical, engineering, finance, government, health

The 19 3D-printable parts that make up the mask are visible on the Maker Mask website along with details on materials needed, download instructions, videos, the ability to donate to the cause and more. The cost of each finished mask, printed in about three hours, is estimated to be between $2 and $3.


A technology veteran and a 3D-printing “savant” have teamed with other members of industry, health care and government to launch Maker Mask, a Seattle nonprofit creating medically endorsed, reusable protective masks using everyday 3D printers.

Continue reading “Maker Mask launches in Seattle using 3D-printing technology to produce protective gear” »

Mar 31, 2020

How to Build a 3D Map of the Universe – and Why

Posted by in categories: computing, quantum physics, space

With quantum radar, you can map the cosmos with 3D modeling and dwave quantum computer.

Mar 31, 2020

Scientists Are Making a 3D Map of the Universe Going Back 11 Billion Years

Posted by in category: space

A telescope in Arizona will undertake the task after being retrofitted with a high-tech sensor.

Mar 31, 2020

Universal cancer blood test detects and locates 50 types of tumors

Posted by in categories: biotech/medical, robotics/AI

Cancer is one of humanity’s leading killers, and the main reason for that is it’s often hard to detect until it’s too late. But that might be about to change. Researchers have developed a new type of AI-powered blood test that can accurately detect over 50 different types of cancer and even identify where it is in the body.

There are just so many types of cancer that it’s virtually impossible to keep an eye out for all of them through routine tests. Instead, the disease usually isn’t detected until doctors begin specifically looking for it, after a patient experiences symptoms. And in many cases, by then it can be too late.

Ideally, there would be a routine test patients can undergo that would flag any type of cancer that may be budding in the body, giving treatment the best shot of being successful. And that’s just what the new study is working towards.

Mar 31, 2020

Two more astronauts join SpaceX’s first crewed mission to the ISS

Posted by in category: space travel

Two more astronauts have been assigned to the first operational crewed flight of SpaceX’s Crew Dragon on a mission to the International Space Station (ISS). NASA astronaut Shannon Walker and Noguchi Soichi, of the Japanese Aerospace Exploration Agency (JAXA), will join NASA astronauts Michael Hopkins and Victor Glover Jr., who were assigned to the mission in 2018. If all goes according to plan, this will be the first in a series of regular Crew Dragon flights to the ISS, NASA said in a press release.

Mar 31, 2020

OneWeb goes bankrupt, lays off staff, will sell satellite-broadband business

Posted by in category: business

OneWeb says pandemic ended chance of getting enough funding for full launch.

Mar 31, 2020

Here’s SpaceX’s plan to help NASA build a moon Gateway and explore space

Posted by in category: space travel

The company is developing an all-new capsule.

Mar 31, 2020

Unearthing gut secret paves way for targeted treatments

Posted by in category: neuroscience

Scientists at Flinders University have, for the first time, identified a specific type of sensory nerve ending in the gut and how these may ‘talk’ to the spinal cord, communicating pain or discomfort to the brain.

This discovery is set to inform the development of new medications to treat problems associated with gut-to-brain communication, paving the way for targeted treatments to mitigate related dysfunction.

While our understanding of the gut’s neurosensory abilities has grown rapidly in recent years, two of the great mysteries have been where and how the different types of sensory nerve endings in the gut lie, and how they are activated.

Mar 31, 2020

How stress remodels the brain

Posted by in category: neuroscience

Stress restructures the brain by halting the production of crucial ion channel proteins, according to research in mice recently published in JNeurosci.

Stress harms the brain and body in profound ways. One way is by altering astrocytes, the brain’s housekeepers tasked with mopping up neurotransmitters after they’ve been released into the synapse. On the cellular level, stress causes the branches of astrocytes to retract from the synapses they wrap around.

Bender et al. investigated what controlled astrocyte changes after mice experienced exposure to the urine of a fox, their natural predator. This single stressful event caused quick but long-lasting retraction of the astrocyte’s branches. Stress induces this change by halting the production of GluA1, an essential subunit of glutamate receptors. During a stressful event, the stress hormone norepinephrine suppresses a molecular pathway that normally culminates in the protein synthesis of GluA1. Without functional GluA1 or glutamate receptors, neurons and astrocytes lose their ability to communicate with each other.