O.,o wut!
A key signal for a certain kind of dark matter failed to turn up in a search throughout the Milky Way. Now scientists are disagreeing about what that means.
Interventions that may slow ageing include drugs (e.g., rapamycin, metformin), supplements (e.g., nicotinamide riboside, nicotinamide mononucleotide), lifestyle interventions (e.g., exercise) and diets (e.g., fasting)
Thanks to advances in modern medicine over the past century, the world’s population has experienced a marked increase in longevity. However, disparities exist that lead to groups with both shorter lifespan and significantly diminished health, especially in the aged. Unequal access to proper nutrition, healthcare services, and information to make informed health and nutrition decisions all contribute to these concerns. This in turn has hastened the ageing process in some and adversely affected others’ ability to age healthfully. Many in developing as well as developed societies are plagued with the dichotomy of simultaneous calorie excess and nutrient inadequacy. This has resulted in mental and physical deterioration, increased non-communicable disease rates, lost productivity and quality of life, and increased medical costs. While adequate nutrition is fundamental to good health, it remains unclear what impact various dietary interventions may have on improving healthspan and quality of life with age. With a rapidly ageing global population, there is an urgent need for innovative approaches to health promotion as individual’s age. Successful research, education, and interventions should include the development of both qualitative and quantitative biomarkers and other tools which can measure improvements in physiological integrity throughout life. Data-driven health policy shifts should be aimed at reducing the socio-economic inequalities that lead to premature ageing. A framework for progress has been proposed and published by the World Health Organization in its Global Strategy and Action Plan on Ageing and Health. This symposium focused on the impact of nutrition on this framework, stressing the need to better understand an individual’s balance of intrinsic capacity and functional abilities at various life stages, and the impact this balance has on their mental and physical health in the environments they inhabit.
There’s an iconic scene in the original Star Wars movie where Luke Skywalker looks out over the desert landscape of Tatooine at the amazing spectacle of a double sunset.
Now, a new study out of the National Radio Astronomy Observatory (NRAO) suggests that such exotic exoplanet worlds orbiting multiple stars may exist in misaligned orbits, far out of the primary orbital plane.
The find has implications for planetary formation in complex multiple star systems. The study used ALMA (the Atacama Large Millimeter/submillimeter Array) in Chile to look at 19 protoplanetary disks around binary stars with longer period orbits, versus a dozen binary stars known to host exoplanets with periods less than 40 days found in the Kepler space telescope observations.
Space can be a horror show of cosmic violence, and now astronomers have captured the first photographic evidence of the carnage that can be unleashed when two heavyweight galaxies collide.
A collaboration between an international team of researchers has produced the first ever image of a relativistic jet of gas and plasma spewing forth from a pair of galaxies as they dive head-first into one another.
While galaxies have been caught mid-collision plenty of times before, this is the first time a jet of this kind has been seen spilling out of such a merger, and it could tell us a thing or two about how they arise.
Whooping cough has made an astonishing comeback, with 2012 seeing nearly 50,000 infections in the U.S. (the most since 1955), and a death rate in infants three times that of the rest of the population. The dramatic resurgence has puzzled public health officials, who have pointed to the waning effectiveness of the current vaccine and growing anti-vaccine sentiment as the most likely culprits.
But that might not be the whole story, suggests a new study published in BMC Medicine by Santa Fe Institute Omidyar Fellows Ben Althouse and Sam Scarpino. Their research points to a different, but related, source of the outbreak — vaccinated people who are infectious but who do not display the symptoms of whooping cough, suggesting that the number of people transmitting without symptoms may be many times greater than those transmitting with symptoms.
In the 1950s, highly successful vaccines based on inactivated pertussis cells (the bacteria that causes whooping cough) drove infection rates in the U.S. below one case per 100,000 people. But adverse side effects of those vaccines led to the development and introduction in the 1990s of acellular pertussis vaccines, which use just a handful of the bacteria’s proteins and bypass most of the side effects. (Currently given to children as part of the Tdap vaccine.)
Circa 2013
These patents form part of Regeneron’s global patent portfolio, which together protect fundamental inventions behind Regeneron’s VelocImmune humanized mice. The two patents listed above specifically contain claims covering genetically modified mice that have unrearranged human immunoglobulin variable region gene segments at endogenous mouse immunoglobulin loci. The VelocImmune mice contain the full repertoire of human heavy chain immunoglobulin genes and kappa light chain genes, each linked to endogenous mouse constant regions. As a result, VelocImmune mice generate a normal and robust immune response which many believe is becoming the gold standard for making human antibody therapeutics. VelocImmune is also proving to be one of the most valuable technologies in biotechnology history, in terms of the licensing and collaboration revenues it has helped generate.
TARRYTOWN, N.Y., Aug. 7, 2013 /PRNewswire/ — Regeneron Pharmaceuticals, Inc. (NASDAQ: REGN) today announced that the United States Patent and Trademark Office granted U.S. Patent No. 8,502,018 relating to methods of genetically modifying a mouse to make human antibodies. A similar European.
Activity Post: Everyone is doing weird facebook activities, so I thought I would give it a try.
This is not a post for sharing anything but information in the comments section. Many like to read, and in a time of boredom reading passes time. I will start by posting a link to cool books to read, and in the comments section mention books you like to read or links of many books you like to read. Two books that changed my life were “Engines of Creation” by K Eric Drexler, and “The Society of Mind”, by Marvin Minsky…in fact name two books that have influenced you, and post a link with cool books to read, as that is more info…and we have no clue how long we will be locked up. Reading often leads to inspiration.
These 16 books like ‘1984’ include invasive rulers, rebels with a cause, and other dystopian themes. Like George Orwell’s novel, they remain with you long after the final page.
The cigar-shaped interstellar visitor to our solar system known as ‘Oumuamua could be the remnants of a larger body that was torn apart by its host star, according to researchers.
The dark, reddish object that hurtled into our solar system in 2017 and was named after the Hawaiian word for messenger or scout has long puzzled scientists.
Among its peculiarities is the lack of an envelope of gas and dust that comets typically give off as they heat up. Further work by experts suggested the body was accelerated by the loss of water vapour and other gases – as seen with comets but not asteroids. The upshot was that ‘Oumuamua was labelled a “comet in disguise”.
Astronomers have used the National Science Foundation’s Karl G. Jansky Very Large Array (VLA) and NASA’s Spitzer Space Telescope to make the first measurement of wind speed on a brown dwarf—an object intermediate in mass between a planet and a star.
Based on facts known about the giant planets Jupiter and Saturn in our own Solar System, a team of scientists led by Katelyn Allers of Bucknell University realized that they possibly could measure a brown dwarf’s wind speed by combining radio observations from the VLA and infrared observations from Spitzer.
“When we realized this, we were surprised that no one else had already done it,” Allers said.
They found it buried in the muddy shores of the Potomac River more than three decades ago: a strange “sediment organism” that could do things nobody had ever seen before in bacteria.
This unusual microbe, belonging to the Geobacter genus, was first noted for its ability to produce magnetite in the absence of oxygen, but with time scientists found it could make other things too, like bacterial nanowires that conduct electricity.
For years, researchers have been trying to figure out ways to usefully exploit that natural gift, and this year they might have hit pay-dirt with a device they’re calling the Air-gen. According to the team, their device can create electricity out of… well, almost nothing.
