Lifeboat Foundation

The pancreas is a key metabolic regulator. When pancreatic beta cells cease producing enough insulin, blood sugar levels rise dangerously — a phenomenon known as hyperglycemia — thus triggering diabetes. After discovering that other mature pancreatic cells can adapt and partly compensate for the lack of insulin, a team from the University of Geneva (UNIGE) demonstrates that the stem cells from which beta cells are derived are only present during embryonic development. This discovery puts an end to a long-standing controversy about the hypothetical existence of adult pancreatic stem cells that would give rise to newly differentiated hormone-producing cells after birth. The scientists also succeeded in precisely defining the ‘identity card’ of pancreatic endocrine cells, which is a promising tool for the production of replacement insulin-secreting cells. These results can be read in Cell Reports and Nature Communications.

Diabetes is a common metabolic disease. It is characterised by a persistent hyperglycemia that occurs when pancreatic cells responsible for the production of insulin — the beta cells — are destroyed or are no longer able to produce this regulatory hormone in sufficient quantities. Since 2010, studies performed by the team of Pedro Herrera, a professor in the Department of Genetic Medicine and Development and in the Diabetes Centre at the UNIGE Faculty of Medicine, as well as at the Geneva Institute of Genetics and Genomics (iGE3), reveal that the other pancreatic endocrine cells — namely alpha, delta and gamma cells, which produce other hormones useful for the metabolic balance — can “learn” to produce insulin when beta cells are absent or defective. This phenomenon, observed in mice and humans, demonstrates the plasticity of pancreatic cells and paves the way to new therapeutic strategies.

3D printed ICs overcome semiconductor shortage and reinforce supply chains, leading to cheaper production costs, faster prototyping, and faster time to market.

As the size of microchip packages shrinks, semiconductor manufacturers are under pressure to improve lithography capabilities. For more than two decades, researchers have been working on 3D printed integrated circuits. Earlier attempts at 3D printing electronics used the proper technique but failed to reach the required levels of conductivity for a PCB, leaving complicated electrical circuits unusable. Over time though, these printing tools have gradually improved feature size resolution, yield, and variability in production.

● A broad variety of materials may be used to produce an assortment of printed electronics, including conductors, semiconductors, dielectrics, resistors, and other components. ● As has been the case in other areas, additive manufacturing is expected to result in more innovative products, lower costs, and faster production runs.

In the sparse collection of atoms that fills interstellar space, Voyager 1 has measured a long-lasting series of waves where it previously only detected sporadic bursts.

Design also poised to save space, retain memory in event of power loss. A new spin on one of the 20th century’s smallest but grandest inventions, the transistor, could help feed the world’s ever-growing appetite for digital memory while slicing up to 5% of the energy from its power-hungry diet.

A new spin on one of the 20th century’s smallest but grandest inventions, the transistor, could help feed the world’s ever-growing appetite for digital memory while slicing up to 5% of the energy from its power-hungry diet.

Following years of innovations from the University of Nebraska–Lincoln’s Christian Binek and University at Buffalos Jonathan Bird and Keke He, the physicists recently teamed up to craft the first magneto-electric transistor.

Along with curbing the energy consumption of any microelectronics that incorporate it, the team’s design could reduce the number of transistors needed to store certain data by as much as 75%, said Nebraska physicist Peter Dowben, leading to smaller devices. It could also lend those microelectronics steel-trap memory that remembers exactly where its users leave off, even after being shut down or abruptly losing power.

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This is not the last blog for this project, but it is perhaps the main blog because it showcases how well the Hammond box works to house the project. I had fun designing the interior chassis to hold all the subsystems in position.

Have you ever heard of the Scandinavian-Mediterranean Corridor? As the fifth of the Trans-European Transport Network’s nine priority axes, it is a critical path for the European economy.

It spans from Finland and Sweden in the north to the island of Malta in the south, passing through Denmark, Northern, Central, and Southern Germany, Northern Italy’s industrial areas, and southern Italian ports.

Continue reading “A gigantic EU tunnel will connect Scandinavia to the Mediterranean. For $11 billion?” »

Access to an online program that provides easily accessible, interactive, tailored healthy lifestyle and behavior change techniques is associated with better health-related quality of life among adult stroke survivors, according to new research from the University of Newcastle and Flinders University.

Stroke can lead to serious consequences for those that survive in terms of physical and cognitive disability. Improving lifestyle and health risk behaviors, including tobacco and alcohol use, physical activity, diet, depression, and anxiety, has the potential to significantly enhance stroke survivors’ quality of life.

Led by Dr. Ashleigh Guillaumier from the University of Newcastle and senior author Professor Billie Bonevski from Flinders University, the study, published in the journal PLOS Medicine, undertook a randomized control trial to evaluate the online program Prevent 2nd Stroke (P2S), which encourages users to set goals and monitor progress across various health risk areas.

Tesla CEO Elon Musk revealed that the automaker has now more than 100,000 people in its Full Self-Driving (FSD) Beta program.

Does it mean that we are going to start seeing an accelerated rate of improvement?

FSD Beta has been a “two steps forward, one step back” type of program.