Lifeboat Foundation

A new therapy that makes the immune system kill bone marrow cancer cells was successful in as many as 73% of patients in two clinical trials, according to researchers from The Tisch Cancer Institute at the Icahn School of Medicine at Mount Sinai.

The therapy, known as a bispecific antibody, binds to both T cells and multiple myeloma cells and directs the T cells— white blood cells that can be enlisted to fight off diseases—to kill multiple myeloma cells. The researchers described this strategy as “bringing your army right to the enemy.”

The success of the off-the-shelf immunotherapy, called talquetamab, was even seen in patients whose cancer was resistant to all approved multiple myeloma therapies. It uses a different target than other approved therapies: a receptor expressed on the surface of cancer cells known as GPRC5D.

In recent years, engineers have been working to develop increasingly sophisticated and smaller electronic components that could power the devices of the future. This includes thin and stretchable components that could be easily worn on the skin or implanted inside the human body.

Researchers at RIKEN, Nanyang Technological University, National University of Singapore, University of Tokyo, and other institutes in Japan, Singapore and China have recently realized a new, elastic electrical conductor that is 1.3-micrometers thin. This conductor, introduced in a paper published in Nature Electronics, could advance the development of both wearable and implantable sensors.

“Ultrathin electronic devices can form a conformal interface with curved surfaces, are not perceivable by human when wearing, and do not induce strong foreign body rejection (FBR) when implanted in animals,” Zhi Jiang, one of the researchers who carried out the study, told TechXplore.

An analysis of 22 large-scale gene expression datasets pointed to exercise and activity in general as the most effective theoretical treatment for reversing gene expressions typical of Alzheimer’s disease. Fluoxetine, a well-known antidepressant, also showed effect, particularly when combined with exercise. Curcumin showed positive effects as well. The study was published in Scientific Reports.

Alzheimer’s disease is a complex neurodegenerative disorder that affects multiple brain regions. It is the most common disease that causes dementia and is very difficult to treat. In the course of the disease, abnormal collections of proteins called tau accumulate inside neurons.

Another type of protein clumps together to form so-called amyloid plaques that collect between neurons and disrupt cell functions. These and other changes harm the functioning of the brain across different regions and lead to dysfunction and death of brain cells.

Following a visit to the UK’s National Quantum Technology Showcase, James McKenzie is excited about the prospects of UK firms developing “quantum 2.0” technology.

2022 the Colorado State Fair’s annual art competition gave out prizes in all the usual art categories.

“Thé tre D’opéra Spatial,” took home the blue ribbon in the fair’s contest for emerging digital artists — making it one of the first A.I.-generated pieces to win such a prize.

Continue reading “Is it ethical to use AI art? Some thought on this topic” »

We still don’t have a clear picture of the Sun’s physics — but the Solar Ring could change that.

To solve this a team of astronomers proposes the Solar Ring. The Solar Ring is a fleet of three spacecraft that will all orbit around the Sun. They will be separated from each other by 120 degrees and be fitted with identical instruments. This way their overlapping fields of view will make it impossible for us to miss anything happening on the surface.

Among the many kinds of observations that the astronomers behind the Solar Ring hope to perform, one involves a technique called reverberation mapping. By carefully mapping the velocity of gas on the surface of the Sun, they can measure vibrations and pulsations. These kinds of “sunquakes” give astronomers rich information about what is happening within deeper layers, much like how earthquakes tell us about the core and mantle of the Earth.

Continue reading “A trio of satellites could take a groundbreaking 360-degree photo of the sun” »

A German-based biotechnologist and filmmaker has presented his concept for an artificial womb. This futuristic device could allow a foetus to grow and develop outside the body, without the need for women to undergo pregnancy.

A s of 1 February 2021, there are about 280 million domestic LPG (liquified petroleum gas) consumers in India, according to Union Minister Dharmendra Pradhan. By March 2022, the Government of India expects that there will be over 300 million consumers. Indian Oil, the country’s largest fuel refiner, claims that it will import 50% more cooking gas to ensure the supply of LPG remains uninterrupted for its bottling plants.

It’s imperative to find heating solutions that are more efficient.

Moreover, the Government of India has been encouraging wider adoption of LPG to replace coal and firewood to improve air quality as well. But according to researchers at IIT-Guwahati, the thermal efficiencies of conventional domestic LPG cooking stoves available in the market are low (60–68%), and emissions are high (CO: 220–550 ppm, NOx: 5–25 ppm).

InvisDefense uses an unusual pattern and irregular heat signals to confuse AI cameras.