The recent design called Proteus by Yves Behar and Fabien Cousteau is a giant under-water research station and habitat. Proteus is planned to be placed underwater, away from the coast of Curaçao, a Dutch Caribbean island.
A typical human cell is metabolically active, roaring with chemical reactions that convert nutrients into energy and useful products that sustain life. These reactions also create reactive oxygen species, dangerous by-products like hydrogen peroxide which damage the building blocks of DNA in the same way oxygen and water corrode metal and form rust. Similar to how buildings collapse from the cumulative effect of rust, reactive oxygen species threaten a genome’s integrity.
Cells are thought to delicately balance their energy needs and avoid damaging DNA by containing metabolic activity outside the nucleus and within the cytoplasm and mitochondria. Antioxidant enzymes are deployed to mop up reactive oxygen species at their source before they reach DNA, a defensive strategy that protects the roughly 3 billion nucleotides from suffering potentially catastrophic mutations. If DNA damage occurs anyway, cells pause momentarily and carry out repairs, synthesizing new building blocks and filling in the gaps.
Despite the central role of cellular metabolism in maintaining genome integrity, there has been no systematic, unbiased study on how metabolic perturbations affect the DNA damage and repair process. This is particularly important for diseases like cancer, characterized by their ability to hijack metabolic processes for unfettered growth.
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WordPress.com is taking on Substack and others with today’s news that its Newsletter product will now support paid subscriptions and premium content. First launched in December, WordPress.com Newsletter allows writers to automatically send out posts via email to connect directly with their audience, while still being able to leverage WordPress.com’s other capabilities. Writers can opt to use the feature solely for newsletters or they can add the option to their blog to cater to readers who want to receive new posts via email instead.
While for years there have been plug-ins and third-party services that allow blog owners to send out their posts via email, WordPress.com’s decision to move more directly into this space was a reflection of how people now prefer to read news and information. As the state of websites has worsened — dominated by clutter, ads, overlays, pop-ups, and cookie acceptance banners — many have turned to email as an easier way to stay connected to writers, journalists, essayists, and other publishers they want to follow.
Given WordPress.com’s sizable footprint — WordPress powers 43% of the web, including its open source version — its shift into the newsletters market is significant.
Discover the intriguing findings that shed light on the significance of brain shape and its influence on brain activity.
Groundbreaking research conducted by a team of Australian scientists suggests that the shape of our brains may affect us more than we think. Nobody wonders if their brain shape is an important parameter. Most people attribute brain size to behaviors even more.
However, it turns out that shape has a more significant impact on our thoughts and behavior than the connections and signals between neurons.
Continue reading “Brain Shape’s surprising impact on thoughts and behavior, study reveals” »
Artificial Intelligence’s growing capacity to generate realistic content, such as deep fakes, is stirring debate in Hollywood over actor compensation and content creation.
The use of artificial intelligence in creating realistic videos has become a contentious issue within Hollywood. Famed director Wes Anderson appears to be part of a trend, as fake movie trailers bearing his distinctive style have popped up on YouTube, featuring significant stars like Bill Murray and Scarlett Johansson. But Anderson or his stars didn’t craft these trailers, and they were generated by AI, stirring debate among actors, writers, and studios.
“Hollywood” by Marcus Vegas is licensed under CC BY-SA 2.0.
Continue reading “AI deepfakes fuel the flames of debate among Hollywood stars” »
Exclusive: Watch the world premiere of the AI-generated short film The Frost
Continue reading “Welcome to the new surreal. How AI-generated video is changing film” »
The International Energy Agency just released its annual investment report. Here’s where the money is going.
Money makes the world go round.
The International Energy Agency just published its annual report on global investment in energy, where it tallies up all that cash. The world saw about $2.8 trillion of investments in energy in 2022, with about $1.7 trillion of that going into clean energy.
Given this new information humans could modify their genetic code to rapidly accelerate their evolution aswell leading to a biological singularity of evolution.
Codfish have been telling a story of rapid fish evolution, reshaped by human activity more swiftly than previously assumed, reveals a cutting-edge study led by Rutgers University.
This evolutionary tale, illuminated during the latter half of the twentieth century, signifies the impact of human-driven overfishing. The findings suggest that evolutionary changes, once thought to span millions of years, can be catalyzed within mere decades.
Continue reading “Fish evolution takes place in decades — not millions of years” »
Infections and other diseases can cause red blood cells to rupture, releasing the oxygen-binding molecule hemoglobin, which breaks down into heme. Free heme can cause significant inflammation and organ damage, leading to morbidity and mortality.
Researchers from St. Jude Children’s Research Hospital discovered NLRP12, an innate immune pattern recognition receptor, to be the key molecule responsible for inducing inflammatory cell death and pathology in response to heme combined with other cellular damage or infection. The finding provides a new potential drug target to prevent morbidity in certain illnesses. The research was published today in Cell.
Many infectious and inflammatory diseases, including malaria or SARS-CoV-2 virus infections and sickle cell disease, cause red blood cells to break apart and spill their contents. The process, hemolysis, releases the hemoglobin. In the bloodstream, hemoglobin then breaks down into a substance called heme.
