Lifeboat Foundation

Almost as soon as there were super-resolution microscopes, scientists pointed them towards molecular motors called kinesins. These proteins, powered by the molecular fuel ATP, drive crucial processes including cell division, cell signalling and intracellular transport by shuttling cargo along protein highways called microtubules. Researchers have long wanted to understand how these motors work, but to visualize them, scientists have had to slow them down or isolate them in simplified, in vitro systems.

Now, in papers published concurrently in Science, two teams working independently have used a super-resolution tool called MINFLUX to study the motor in near-real time at physiologically relevant concentrations of ATP. The first paper, led by MINFLUX’s inventor, Stefan Hell, who has a joint appointment at the Max Planck Institute (MPI) for Multidisciplinary Sciences in Göttingen and the MPI for Medical Research in Heidelberg, both in Germany, used a new instrument design to track the protein in 3D, revealing details about its motion¹. The second, led by biophysicist Jonas Ries at the European Molecular Biology Laboratory in Heidelberg, showed for the first time that MINFLUX is capable of tracking kinesin even amid the bustle of living cells².

“This technology requires a lot of different things to work, and it’s fun to see all of these things coming together,” says Michelle Digman, a biomedical engineer at the University of California, Irvine, who develops imaging strategies but was not involved in either study. “It seemed like a proof of concept to show that they’re able to track kinesin very precisely. And when you have the live cell system, that’s even more spectacular.”

One might say that C was replaced by C++, which was later replaced by Python. Now we have prompt engineering to replace Python.

As a philosophy student, I was bewitched by the power of reason – but my life is freer since I escaped from its spell.

The Futures Conference is coming to Sydney, Australia. Metaverse means Community. Technology is the pathway to the Future. The Arts meets Science meets Tech meets Business.

https://www.youtube.com/@ForesightInstitute/videos

Is a research organization and non-profit that supports the beneficial development of high-impact technologies. Since our founding in 1987 on a vision of guiding powerful technologies, we have continued to evolve into a many-armed organization that focuses on several fields of science and technology that are too ambitious for legacy institutions to support.

From molecular nanotechnology, to brain-computer interfaces, space exploration, cryptocommerce, and AI, Foresight gathers leading minds to advance research and accelerate progress toward flourishing futures.

China has reached reportedly a secret deal with Cuba, under the deal China would be allowed to install an electronic eavesdropping facility on the island nation. This has surely become a matter for Washington.

But as the typical mutual fund disclaimer so famously states, past performance is no guarantee of future results. It’s time to rethink our love affair with depth. The pendulum between depth and breadth has swung too far in favor of depth.

There’s an oft-quoted saying that “to a man with a hammer, everything looks like nails.” But what if that man had a hammer, a screwdriver, and a wrench? Might he or she look to see if the flat top had a narrow slit, suggesting the use of a screwdriver? Or perhaps consider the shape of the flat top. Circle? Hexagon? Could a wrench be a more effective tool? And finally, the mere addition of these tools can encourage a better understanding of a problem.

This is not to suggest that deep expertise is useless. Au contraire. Carrying a hammer is not a problem. It’s just that our world is changing so rapidly that those with more tools in their possession will better navigate the uncertainty. To make it in today’s world, it’s important to be agile and flexible.

June 8 (Reuters) — Alphabet’s (GOOGL.O) Google and Microsoft (MSFT.O) are inserting ads into AI experiments without providing an option to opt out of participation, an approach that has already rankled some brands and risks further pushback from the industry, ad buyers told Reuters.

The two tech giants are racing to revamp their search engines with artificial intelligence that can produce written responses to open-ended queries. That process will upend how advertisers reach consumers through ads on search results, a market that is estimated to grow 10% to $286 billion this year, according to research firm MAGNA.

Microsoft is testing ads in the Bing AI chatbot, which began rolling out to users in February, by relocating some traditional search ads and inserting them into the AI responses, the company said.

In May, 11,865 new passenger plug-in cars were registered in Norway (up 21% year-over-year), which is about 88.9% of the total volume.