Lifeboat Foundation

While the advent of immunotherapy has revolutionized cancer treatment, its use in the treatment of glioblastoma (GBM) has been less successful. Most studies using immunotherapy in GBM have been negative and the reasons for this are still being studied. In clinical practice, interpreting response to immunotherapy has been challenging, particularly when trying to differentiate between treatment-related changes (i.e., pseudoprogression) or true tumor progression. T cell tagging is one promising technique to noninvasively monitor treatment efficacy by assessing the migration, expansion, and engagement of T cells and their ability to target tumor cells at the tumor site.

The team, led by Professor Magdalena Zernicka-Goetz, developed the embryo model without eggs or sperm, and instead used stem cells – the body’s master cells, which can develop into almost any cell type in the body.

The researchers mimicked natural processes in the lab by guiding the three types of stem cells found in early mammalian development to the point where they start interacting. By inducing the expression of a particular set of genes and establishing a unique environment for their interactions, the researchers were able to get the stem cells to ‘talk’ to each other.

Researchers have created model embryos from mouse stem cells that form a brain, a beating heart, and the foundations of all the other organs of the body.

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Walmart, Meta and LinkedIn are three companies currently testing internal generative AI options for employees that are safe for the use of company data, either in the form of generative AI “playgrounds” that offer a variety of models to choose from, or in the case of Meta, its own in-house internal chatbot.

These examples stand in contrast to companies that have banned the use of public generative AI tools like ChatGPT, including Goldman Sachs, Amazon and Verizon.

Denmark was in full chaotic collapse in the early 19th century. Why was its art so beautifully serene?

Bengaluru-based Professor Saji Varghese founded a startup called Sunbird Straws, which sells eco-friendly straws made from coconut leaves. So far, the company has sold over 20 million pieces worldwide.

Scientists have taken a journey back in time to unlock the mysteries of Earth’s early history, using tiny mineral crystals called zircons to study plate tectonics billions of years ago. The research sheds light on the conditions that existed in early Earth, revealing a complex interplay between Earth’s crust, core, and the emergence of life.

Plate tectonics allows heat from Earth’s interior to escape to the surface, forming continents and other geological features necessary for life to emerge. Accordingly, “there has been the assumption that plate tectonics is necessary for life,” says John Tarduno, who teaches in the Department of Earth and Environmental Sciences at the University of Rochester. But new research casts doubt on that assumption.

Tarduno, the William R. Kenan, Jr. Professor of Geophysics, is lead author of a paper published in Nature examining plate tectonics from a time 3.9 billion years ago, when scientists believe the first traces of life appeared on Earth.

TOPEKA, Kan. (KSNT) — Multiple packages of frozen fruit, specifically strawberries, are being recalled due to possible Hepatitis A contamination.

The Food and Drug Administration said Willamette Valley Fruit Co. of Salem, Oregon, is voluntarily recalling select packages of frozen strawberries and a frozen fruit blend containing strawberries. The impacted strawberries were grown in Mexico and are potentially carrying Hepatitis A.

Hepatitis A is a contagious liver disease caused by the Hepatitis A virus, which can be spread through close contact with someone who is infected, or by eating foods or consuming beverages that have been contaminated, according to the CDC.

COPENHAGEN, June 14 (Reuters) — Swedish electric self-driving truck company Einride expects to reduce CO₂ emissions in Norway by 2,100 tonnes over the coming three years as it partners up with Scandinavia’s leading postal service, PostNord, the company said on Wednesday.

Norway has the world’s highest number of electric vehicles per head of population and aims for all heavy vehicles to be zero-emission by 2040, potentially cutting CO₂ emissions by 4.4 million tonnes or nearly 9% of the country’s annual emissions.

“Given Norway’s pioneering work in electrifying passenger vehicles, it’s only logical that they should take a leading role in the electrification of heavy-duty freight as well,” Einride CEO Robert Falck said.

Dan this made me think of you.

‘Benchmark’ experiment suggests quantum computers could have useful real-world applications within two years.