Lifeboat Foundation

Cognitive dysfunction in aging is a major biomedical challenge. Whether treatment with klotho, a longevity factor, could enhance cognition in human-relevant models such as in nonhuman primates is unknown and represents a major knowledge gap in the path to therapeutics. We validated the rhesus form of the klotho protein in mice showing it increased synaptic plasticity and cognition. We then found that a single administration of low-dose, but not high-dose, klotho enhanced memory in aged nonhuman primates. Systemic low-dose klotho treatment may prove therapeutic in aging humans.

In people with the variant, past exposure to other coronaviruses may prep the immune system to fight off the disease.

NIH-funded clinical trial finds cholesterol-lowering treatment reduced cardiovascular events by 35%.

A National Institute of Health-supported study found that statins, a class of cholesterol-lowering medications, may offset the high risk of cardiovascular disease in people living with HIV by more than a third, potentially preventing one in five major cardiovascular events or premature deaths in this population. People living with HIV can have a 50–100% increased risk for cardiovascular disease. The findings are published in the New England Journal of Medicine.

The Atlantic meridional overturning circulation (AMOC) is a major tipping element in the climate system. Here, data-driven estimators for the time of tipping predict a potential AMOC collapse mid-century under the current emission scenario.

Scientists at the Niels Bohr Institute, in cooperation with the University of Münster and Ruhr-Universität Bochum, developed new technology capable of processing the enormous amounts of information quantum systems generate. They’ve successfully linked deterministic single-photon.

A photon is a particle of light. It is the basic unit of light and other electromagnetic radiation, and is responsible for the electromagnetic force, one of the four fundamental forces of nature. Photons have no mass, but they do have energy and momentum. They travel at the speed of light in a vacuum, and can have different wavelengths, which correspond to different colors of light. Photons can also have different energies, which correspond to different frequencies of light.

A Yale-led team of physicists has discovered a circular pattern in the movement of electrons in a group of quantum materials known as “strange metals.”

This is a good use of AI. Definitely regular it but I can see it’s contributing to medical research.

Summary: Researchers have utilized artificial intelligence to uncover the promising potential of extra virgin olive oil (EVOO) in combating Alzheimer’s disease (AD).

By integrating AI, chemistry, and omics research, the study identified specific bioactive compounds in EVOO that could contribute to the treatment and prevention of AD. Ten phytochemicals within EVOO, such as quercetin, genistein, luteolin, and kaempferol, were found to exhibit potential impacts on AD protein networks.

Continue reading “AI Unlocks Olive Oil’s Potential in Alzheimer’s Battle” »

🎧 Spotify: https://open.spotify.com/playlist/1wbWOquWfBkZhj33OWgvXw?si=bf899f1ae4f6455b

Graphene is a two-dimensional wonder material that has been suggested for a wide range of applications in energy, technology, construction, and more since it was first isolated from graphite in 2004.

This single layer of carbon atoms is tough yet flexible, light but with high resistance, with graphene calculated to be 200 times more resistant than steel and five times lighter than aluminum.

Graphene may sound perfect, but it very literally is not. Isolated samples of this 2D allotrope aren’t perfectly flat, with its surface rippled. Graphene can also feature structural defects that can, in some cases, be deleterious to its function and, in other instances, can be essential to its chosen application. That means that the controlled implementation of defects could enable fine-tuning of the desired properties of two-dimensional crystals of graphene.