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Oct 29, 2007

One shot Gene therapy protection from radiation

Posted by in categories: defense, existential risks, futurism, lifeboat, nuclear weapons

University of Pittsburgh researchers injected a therapy previously found to protect cells from radiation damage into the bone marrow of mice, then dosed them with some 950 roentgens of radiation — nearly twice the amount needed to kill a person in just five hours. Nine in 10 of the therapy-receiving mice survived, compared to 58 percent of the control group.

Between 30 and 330 days, there were no differences in survival rates between experiment and control group mice, indicating that systemic MnSOD-PL treatment was not harmful to survival.

The researchers will need to verify whether this treatment would work in humans.

This is part of the early development in the use of genetic modification to increase the biological defences (shields) of people against nuclear, biological and chemical threats. We may not be able to prevent all attacks, so we should improve our toughness and survivability. We should still try to stop the attacks and create the conditions for less attacks.

Oct 25, 2007

Overview: Biological Weapons Convention

Posted by in categories: biological, treaties

(Source: Wikipedia)

Full name: Convention on the Prohibition of the Development, Production and Stockpiling of Bacteriological (Biological) and Toxin Weapons and on their Destruction

Short name: Biological Weapons Convention (BWC)
Open for signature: April 10, 1972
Entered into force: March 26, 1975
Member states: 158
Map of member states:

Continue reading “Overview: Biological Weapons Convention” »

Oct 18, 2007

ETC Group: Action Group on Erosion, Technology and Concentration

Posted by in category: biotech/medical

I’ve been taking a look at an “international civil society organization” called the ETC Group. The “ETC” group is also known as the “Action Group on Erosion, Technology and Concentration”. To be honest, I can’t figure them out. Here is a summary:

“ETC Group is an international civil society organization based in Canada. We are dedicated to the conservation and sustainable advancement of cultural and ecological diversity and human rights. ETC Group supports socially responsible development of technologies useful to the poor and marginalized and we address international governance issues affecting the international community. We also monitor the ownership and control of technologies and the consolidation of corporate power.”

So they look like a somewhat standard leftist environmentalist technology oversight group. Alright.

Continue reading “ETC Group: Action Group on Erosion, Technology and Concentration” »

Oct 16, 2007

Lifeboat Foundation Fellow wins Feynman Prize

Posted by in categories: biotech/medical, lifeboat, nanotechnology

Robert Freitas, Jr., Lifeboat Foundation Fellow and head of the Lifeboat Foundation’s Nanomedicine Division has won the 2007 Foresight Institute Feynman Prize in Communication.

Dr. Pearl Chin, President of the Foresight Nanotech Institute, said Freitas received the award for “pioneering the study and communication of the benefits to be obtained from an advanced nanomedicine that will be made possible by molecular manufacturing [and for having] worked to develop and communicate a path from our current technology base to a future technology base that will enable advanced nanomedicine.”

Prior to his Feynman Prize win Robert shared the Lifeboat Foundation’s 2006 Guardian Award with technology legend Bill Joy. Freitas and Joy shared the Guardian award for their many years of work on mitigating risks posed by advanced technologies.

Oct 15, 2007

Structure of influenza B virus protein gives clues to next pandemic

Posted by in categories: biological, defense, existential risks, lifeboat

Determining the structure of a protein called hemagglutinin on the surface of influenza B is giving researchers at Baylor College of Medicine and Rice University in Houston clues as to what kinds of mutations could spark the next flu pandemic.

This is interesting research and progress in understanding and possibly blocking changes that would lead to pandemics.

In a report that goes online today in the Proceedings of the National Academy of Sciences (PNAS), Drs. Qinghua Wang, assistant professor of biochemistry and molecular biology at BCM, and Jianpeng Ma, associate professor in the same department and their colleagues describe the actual structure of influenza B virus hemagglutinin and compare it to a similar protein on influenza A virus. That comparison may be key to understanding the changes that will have to occur before avian flu (which is a form of influenza A virus) mutates to a form that can easily infect humans, said Ma, who holds a joint appointment at Rice. He and Wang have identified a particular residue or portion of the protein that may play a role in how different types of hemagglutinin bind to human cells.

“What would it take for the bird flu to mutate and start killing people” That’s the next part of our work,” said Ma. Understanding that change may give scientists a handle on how to stymie it.

Continue reading “Structure of influenza B virus protein gives clues to next pandemic” »

Oct 9, 2007

Inflatable Mirrors on spacecraft would move asteroids fastest

Posted by in categories: asteroid/comet impacts, defense, existential risks, lifeboat, space

New Scientist reports on a new study by researchers led by Massimiliano Vasile of the University of Glasgow in Scotland have compared nine of the many methods proposed to ward off such objects, including blasting them with nuclear explosions.

The team assessed the methods according to three performance criteria: the amount of change each method would make to the asteroid’s orbit, the amount of warning time needed and the mass of the spacecraft needed for the mission.

The method that came out on top was a swarm of mirror-carrying spacecraft. The spacecraft would be launched from Earth to hover near the asteroid and concentrate sunlight onto a point on the asteroid’s surface.

In this way, they would heat the asteroid’s surface to more than 2100° C, enough to start vaporising it. As the gases spewed from the asteroid, they would create a small thrust in the opposite direction, altering the asteroid’s orbit.

Continue reading “Inflatable Mirrors on spacecraft would move asteroids fastest” »

Oct 2, 2007

Geoengineering: A Cure for Global Warming

Posted by in categories: engineering, sustainability



Two of Britain’s leading environmental thinkers say it is time to develop a quick technical fix for climate change. Writing in the journal Nature, Science Museum head Chris Rapley and Gaia theorist James Lovelock suggest looking at boosting ocean take-up of CO2.

Floating pipes reaching down from the top of the ocean into colder water below move up and down with the swell.

As the pipe moves down, cold water flows up and out onto the ocean surface. A simple valve blocks any downward flow when the pipe is moving upwards.

Colder water is more “productive” — it contains more life, and so in principle can absorb more carbon.

Finally some practical solutions are being introduced to mitigate global warming. The BBC article mention the US company, Atmocean, that is already testing such a system.

Read the articles from BBC or the New York Times based on the same article from Nature.

Sep 27, 2007

SCADA (in)Security’s Going to Cost Us

Posted by in categories: cybercrime/malcode, defense, existential risks

When I read about the “Aurora Generator Test” video that has been leaked to the media I wondered “why leak it now now and who benefits.” Like many of you, I question the reasons behind any leak from an “unnamed source” inside the US Federal government to the media. Hopefully we’ll all benefit from this particular leak.

Then I thought back to a conversation I had at a trade show booth I was working in several years ago. I was speaking with a fellow from the power generation industry. He indicated that he was very worried about the security ramifications of a hardware refresh of the SCADA systems that his utility was using to control its power generation equipment. The legacy UNIX-based SCADA systems were going to be replaced by Windows based systems. He was even more very worried that the “air gaps” that historically have been used to physically separate the SCADA control networks from power company’s regular data networks might be removed to cut costs.

Thankfully on July 19, 2007 the Federal Energy Regulatory Commission proposed to the North American Electric Reliability Corporation a set of new, and much overdue, cyber security standards that will, once adopted and enforced do a lot to help make an attacker’s job a lot harder. Thank God, the people who operate the most critically important part of our national infrastructure have noticed the obvious.

Hopefully a little sunlight will help accelerate the process of reducing the attack surface of North America’s power grid.

After all, the march to the Singularity will go a lot slower without a reliable power grid.

Matt McGuirl, CISSP

Sep 27, 2007

New field-deployable biosensor detects avian influenza virus in minutes instead of days

Posted by in categories: biological, defense, lifeboat

A new biosensor developed at the Georgia Tech Research Institute (GTRI) can detect avian influenza in just minutes. In addition to being a rapid test, the biosensor is economical, field-deployable, sensitive to different viral strains and requires no labels or reagents.

This kind of technology could be applied to real time monitoring of other diseases as well.


Photograph of the optical biosensor that is approximately 16 millimeters by 33 millimeters in size. The horizontal purple lines are the channels on the waveguide. Credit: Gary Meek

“We can do real-time monitoring of avian influenza infections on the farm, in live-bird markets or in poultry processing facilities,” said Jie Xu, a research scientist in GTRI’s Electro-Optical Systems Laboratory (EOSL)

Continue reading “New field-deployable biosensor detects avian influenza virus in minutes instead of days” »

Sep 6, 2007

The Other Side of the Immortality Coin

Posted by in category: existential risks

There are two sides to living as long as possible: developing the technologies to cure aging, such as SENS, and preventing human extinction risk, which threatens everybody. Unfortunately, in the life extensionist community, and the world at large, the balance of attention and support is lopsided in favor of the first side of the coin, while largely ignoring the second. I see people meticulously obsessed with caloric restriction and SENS, but apparently unaware of human extinction risks. There’s the global warming movement, sure, but no efforts to address the bio, nano, and AI risks.

It’s easy to understand why. Life extension therapies are a positive and happy thing, whereas existential risk is a negative and discouraging thing. The affect heuristic causes us to shy away from negative affect, while only focusing on projects with positive affect: life extension. Egocentric biases help magnify the effect, because it’s easier to imagine oneself aging and dying than getting wiped out along with billions of others as a result of a planetary plague, for instance. Attributional biases work against both sides of the immortality coin: because there’s no visible bad guy to fight, people aren’t as juiced up as they would be, about, say, protesting a human being like Bush.

Another element working against the risk side of the coin is the assignment of credit: a research team may be the first to significantly extend human life, in which case, the team and all their supporters get bragging rights. Prevention of existential risks is a bit hazier, consisting of networks of safeguards which all contribute a little bit towards lowering the probability of disaster. Existential risk prevention isn’t likely to be the way it is in the movies, where the hero punches out the mad scientist right before he presses the red button that says “Planet Destroyer”, but because of a cooperative network of individuals working to increase safety in the diverse areas that risks could emerge from: biotech, nanotech, and AI.

Present-day immortalists and transhumanists simply don’t care enough about existential risk. Many of them are at the same stage with regards to ideological progression as most of humanity is against the specter of death: accepting, in denial, dismissive. There are few things less pleasant to contemplate than humanity destroying itself, but it must be done anyhow, because if we slip and fall, there’s no getting up.

Continue reading “The Other Side of the Immortality Coin” »