Lifeboat Foundation

Could we actually start seeing some standards around CRISPR being proposed & implemented around CRISPR?

Bethesda, MD –This SRC will present the very latest developments in this field, with talks by leading international experts working with both prokaryotic and eukaryotic models. This unique blend from the two communities is always much appreciated by attendees of this meeting and one of its main highlights. The topics covered will include events occurring at both the 5’ and 3’ ends of mRNA related to decay, the links between translation, quality control and mRNA stability, and the relationship between RNA degradation and disease. Two full sessions will be devoted to mechanisms of sRNA, CRISPR RNA and miRNA regulation and how they pertain to mRNA stability. The meeting is traditionally of a very manageable size (typically about 120 attendees), providing unrestricted access to students and post-docs for dynamic discussions with more established scientists and potential future employers. Informal Meet the Expert sessions will be held over lunch, with assigned tables to selected speakers.

There will be a total of 9 very broad-ranging sessions over the 4 days, with 36 invited speakers at the top of their fields and two internationally renowned keynote speakers, Chris Lima and Jörg Vogel. Speakers are encouraged to present their most recent and unpublished data. There will be two poster sessions and 2–3 additional speakers per session will be chosen to give oral presentations, based on the submitted abstracts. This promises to be a very interesting and lively meeting in one of Europe’s most beautiful cities. We hope to see you there!

Continue reading “Post-transcriptional control of gene expression: mRNA decay” »

Now, this is intriguing — pathways are a critical part of our system that monitors and manages how our bodies respond and interact to changes in our bodies. This recent SRC report focuses on the researchers efforts in monitoring pathways and how defects in pathways contribute to the biology and pathophysiology of cancer.

Bethesda, MD — This SRC focuses on new developments in the biology of lipid signaling with an emphasis on cancer, neuronal and cardiovascular diseases. The emphasis will be on molecular, cellular, structure/function and enzymatic mechanisms of physiological signaling pathways and how defects in these pathways contribute to the biology and pathophysiology of cancer, neurodegeneration and cardiovascular disease. The focus will be on how diacylglycerol, phosphatidic acid, lysophospholipids, sphingolipids and phosphoinositide lipids modulate specific pathways and processes in the contexts of physiological growth-regulatory signals, intracellular and extracellular vesicular trafficking, regulation of cell polarization, migration, motility and invasion, autophagy and epithelial extrusion, and as nuclear regulators of mRNA processing and gene expression. These sessions will include discussions on how signaling becomes dysfunctional in diseases. There will be presentations on new translational approaches and therapeutic targets. There will be significant representation from the pharmaceutical and biotechnology industry in order to facilitate networking between industry and academia. The topic areas have been chosen to maximize discussion of provocative and important developments.

We particularly wish to encourage the participation of new and junior researchers in the field and are securing additional support to provide PhD/postdoctoral fellow travel awards. Organizers have kept multiple short session speaking slots open. These will be selected from novel advances during 2015–2016 and from submitted abstracts. There will be multiple opportunities for new investigators and postdoctoral fellows to present and discuss their work including at poster sessions, short talks and short 5–10 minute oral ‘research snapshots’ to highlight their submitted abstracts. There will be multiple poster sessions during the conference. Time will also be allocated to at least two “meet the expert sessions” wherein established research leaders will dedicate time to interact with trainees and new investigators, specifically to give advice concerning the science and possible prospects for postdoctoral training, research funding, publishing or employment tracks.

Continue reading “Phospholipid signaling in cancer, neurodegeneration and cardiovascular disease” »

Unbelievable

A patient playing guitar looks odd in a surgery but actually helps doctors detect his brain signals.

A 57-year-old guitar musician received a brain operation in Shenzhen on Jan 25 as he played his guitar through the whole session.

The patient suffered a rare neurological disease called musician’s dystonia.

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Existing off-the-shelf components are all you need to spy like the NSA, says a UC Berkeley researcher.

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I do indeed think it solves he firewall problem, kind of trivially so. I am somewhat puzzled they didn’t even mention this in their paper.

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The cosmos came into sharper focus this week with astronomers releasing the highest resolution astronomical image yet. The product of 15 earthbound radio telescopes and a Russian satellite, the image of a black hole in a galaxy 900 millions light years away is detailed enough to show the equivalent of a US 50-cent piece on the Moon.

According to Instituto de Astrofísica de Andalucía (IAA-CSIC), which is leading the project, the image is the product of six European radio telescopes, the nine dishes of the US National Science Foundation’s Very Long Baseline Array (VLBA), and the Spektr-R satellite of the RadioAstron mission.

Continue reading “Astronomers generate image equivalent to telescope 63,000 miles wide” »

Finally. Bionic eye technology that could give sight back to millions of individuals worldwide is set to start trials.

Adding to the recent buzz surrounding the development of bionic eye systems is news of scientists from Australia who are set to begin trials on The Phoenix99 bionic eye—a fully implantable system that marks a significant breakthrough in neural stimulation technology.

Continue reading “Australian Scientists Will Soon Begin Trials for a Fully Implantable Bionic Eye” »

The greatest invention of our era? The internet.

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It’s not a smoking gun. But in this week’s Nature, there’s a study that strongly links schizophrenia with a double-agent gene involved in the immune system.

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