Two early clinical trials that together included nine patients suggest that a treatment called CAR-T therapy could treat glioblastoma, but its long-term effects are unknown.
According to the CDC, more than 140,000 Americans are dying each year from alcohol-related causes, and the rate of deaths has been rising for years, especially during the pandemic.
The idea: For occasional drinkers, alcohol causes the brain to release more dopamine, a chemical that makes you feel good. Chronic alcohol use, however, causes the brain to produce, and process, less dopamine, and this persistent dopamine deficit has been linked to alcohol relapse.
There is currently no way to reverse the changes in the brain brought about by AUD, but a team of US researchers suspected that an in-development gene therapy for Parkinson’s disease might work as a dopamine-replenishing treatment for alcoholism, too.
A rigorous analysis of numerous studies concludes that a part of the brain traditionally associated with movement is abnormal in children with developmental language impairments, according to Georgetown University Medical Center neuroscientists. The discovery has the potential to improve both the diagnosis and treatment of the language difficulties.
The researchers investigated brain abnormalities in developmental language disorder. This condition, which impacts the development of various aspects of language, is about as common as attention-deficit/hyperactivity disorder (ADHD) and dyslexia, and more prevalent than autism. The scientists found that abnormalities occurred specifically in the anterior neostriatum within the basal ganglia, a structure found deep in the brain.
They describe their findings in Nature Human Behaviour on March 15.
They treated three patients with recurrent glioblastoma using a variant of an existing CAR-T therapy, adding additional antibodies to the treatment — and the results were truly astounding.
According to the paper published in The New England Journal of Medicine, one patient saw their tumor decrease in size by 18.5% two days after the treatment, and by day 69, the tumor had decreased by 60.7%, while another saw their ‘tumor regress rapidly’, according to Mass General Brigham.
After the third patient was treated, an MRI showed that a single infusion had led to a ‘near-complete tumor regression’ in just five days.
Here are 10 signs to look for if you suspect a loved one may have Alzheimer’s disease:
If you suspect a loved one may have Alzheimer’s disease, here are 10 signs to look for from WebMD.
Joint research led by Yu Toyoshima and Yuichi Iino of the University of Tokyo has demonstrated individual differences in, and successfully extracted commonalities from, the whole-brain activity of roundworms. The researchers also found that computer simulations based on the whole-brain activity of roundworms more accurately reflect real-brain activity when they include so-called “noise,” or probabilistic elements. The findings were published in the journal PLOS Computational Biology.
The roundworm Caenorhabditis elegans is a favorite among neuroscientists because its 302 neurons are completely mapped. This gives a fantastic opportunity to reveal their neural mechanism at a systems level. Thus far, scientists have been making progress in revealing the different states and patterns of each neuron and the assemblies they form. However, how these states and patterns are generated has been a less explored frontier.
A collaborative project to bring the promise of cell therapy to patients with a deadly form of brain cancer has shown dramatic results among the first patients to receive the novel treatment.
In a paper published Wednesday in The New England Journal of Medicine, researchers from Mass General Cancer…
Cutting-edge therapy shrinks tumors in early glioblastoma trial.
Continue reading “‘Dramatic’ inroads against aggressive brain cancer” »
Groundbreaking graphene neurotechnology developed by ICN2 and collaborators promises transformative advances in neuroscience and medical applications, demonstrating high-precision neural interfaces and targeted nerve modulation.
A study published in Nature Nanotechnology presents an innovative graphene-based neurotechnology with the potential for a transformative impact in neuroscience and medical applications. This research, spearheaded by the Catalan Institute of Nanoscience and Nanotechnology (ICN2) together with the Universitat Autònoma de Barcelona (UAB) and other national and international partners, is currently being developed for therapeutic applications through the spin-off INBRAIN Neuroelectronics.
Key Features of Graphene Technology.
Chinese ambassador Chen Xu called for the high-quality development of artificial intelligence (AI), assistance in promoting children’s mental health, and protection of children’s rights while delivering a joint statement on behalf of 80 countries at the 55th session of the United Nations Human Rights Council (UNHRC) on Thursday.
Chen, China’s permanent representative to the UN Office in Geneva and other international organizations in Switzerland, said that artificial intelligence is a new field of human development and should adhere to the concept of consultation, joint construction, and shared benefits, while working together to promote the governance of artificial intelligence.
The new generation of children has become one of the main groups using and benefiting from AI technology. The joint statement emphasized the importance of children’s mental health issues.
A device in her brain delivers jolts of electricity when it detects abnormal neural activity associated with obsessive thoughts.
