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A team led by University of Minnesota Twin Cities researchers has discovered a groundbreaking one-step process for creating materials with unique properties, called metamaterials. Their results show the realistic possibility of designing similar self-assembled structures with the potential of creating “built-to-order” nanostructures for wide application in electronics and optical devices.

The research was published and featured on the cover of Nano Letters, a peer-reviewed scientific journal published by the American Chemical Society.

In general, metamaterials are materials made in the lab so as to provide specific physical, chemical, electrical, and optical properties otherwise impossible to find in naturally occurring materials. These materials can have unique properties which make them ideal for a variety of applications from optical filters and medical devices to aircraft soundproofing and infrastructure monitoring. Usually these nano-scale materials are painstakingly produced in a specialized clean room environment over days and weeks in a multi-step fabrication process.

In a technique known as DNA origami, researchers fold long strands of DNA over and over again to construct a variety of tiny 3D structures, including miniature biosensors and drug-delivery containers. Pioneered at the California Institute of Technology in 2006, DNA origami has attracted hundreds of new researchers over the past decade, eager to build receptacles and sensors that could detect and treat disease in the human body, assess the environmental impact of pollutants, and assist in a host of other biological applications.

Although the principles of DNA origami are straightforward, the technique’s tools and methods for designing new structures are not always easy to grasp and have not been well documented. In addition, scientists new to the method have had no single reference they could turn to for the most efficient way of building DNA structures and how to avoid pitfalls that could waste months or even years of research.

That’s why Jacob Majikes and Alex Liddle, researchers at the National Institute of Standards and Technology (NIST) who have studied DNA origami for years, have compiled the first detailed tutorial on the technique. Their comprehensive report provides a step-by-step guide to designing DNA origami nanostructures, using state-of-the-art tools. Majikes and Liddle described their work in the Jan .8 issue of the Journal of Research of the National Institute of Standards and Technology.

Before the pandemic, the lab of Stanford University biochemist Peter S. Kim focused on developing vaccines for HIV, Ebola and pandemic influenza. But, within days of closing their campus lab space as part of COVID-19 precautions, they turned their attention to a vaccine for SARS-CoV-2, the virus that causes COVID-19. Although the coronavirus was outside the lab’s specific area of expertise, they and their collaborators have managed to construct and test a promising vaccine candidate.

“Our goal is to make a single-shot vaccine that does not require a cold-chain for storage or transport. If we’re successful at doing it well, it should be cheap too,” said Kim, who is the Virginia and D. K. Ludwig Professor of Biochemistry. “The target population for our vaccine is low-and middle-income countries.”

Their vaccine, detailed in a paper published in ACS Central Science (“A Single Immunization with Spike-Functionalized Ferritin Vaccines Elicits Neutralizing Antibody Responses against SARS-CoV-2 in Mice”), contains nanoparticles studded with the same proteins that comprise the virus’s distinctive surface spikes.

I think the larger the galactic population the more deterrence will be a factor of survival. IMO the key apparatus for survival is not only nanotechnology on a personal level but to become Dysonian so we have the energy for defense.

In this video, Unveiled takes a terrifying journey into the Dark Forest! Why don’t you come along??

Continue reading “Are We Living in the Dark Forest? | Unveiled” »

Reactive molecules, such as free radicals, can be produced in the body after exposure to certain environments or substances and go on to cause cell damage. Antioxidants can minimize this damage by interacting with the radicals before they affect cells.

Led by Enrique Gomez, professor of chemical engineering and materials science and engineering, Penn State researchers have applied this concept to prevent imaging damage to conducting polymers that comprise soft electronic devices, such as organic solar cells, organic transistors, bioelectronic devices and flexible electronics. The researchers published their findings in Nature Communications today (Jan. 8).

According to Gomez, visualizing the structures of conducting polymers is crucial to further develop these materials and enable commercialization of soft electronic devices—but the actual imaging can cause damage that limits what researchers can see and understand.

O,.o circa 2020.

Their quantum phase battery consists of an n-doped InAs nanowire forming the core of the battery (the pile) and Al superconducting leads as poles. It is charged by applying an external magnetic field, which then can be switched off.

Cristina Sanz-Fernández and Claudio Guarcello, also from CFM, adapted the theory to simulate the experimental findings.

Continue reading “The World’s First Quantum Phase Battery Is Here” »

Lawrence Livermore National Laboratory (LLNL) researchers have discovered that carbon nanotube membrane pores could enable ultra-rapid dialysis processes that would greatly reduce treatment time for hemodialysis patients.

The ability to separate molecular constituents in complex solutions is crucial to many biological and man-made processes. One way is via the application of a concentration gradient across a porous membrane. This drives ions or molecules smaller than the pore diameters from one side of the membrane to the other while blocking anything that is too large to fit through the pores.

In nature, biological membranes such as those in the kidney or liver can perform complex filtrations while still maintaining high throughput. Synthetic membranes, however, often struggle with a well-known trade-off between selectivity and permeability. The same material properties that dictate what can and cannot pass through the membrane inevitably reduce the rate at which filtration can occur.

University of Wyoming researchers demonstrated their method using a traditional microwave oven. Read it here.

Every year, over a million people develop health care-acquired infections during their hospital stays. And around 100000 of them die from those complications.

But researchers at the University of Georgia are determined to change that, and their new study shows a promising tool for preventing infections before they happen.

Continue reading “Building safer medical devices with innovative protective nanoparticle coating” »