Lifeboat Foundation

Fascinating article, and a mostly fair one at that!

“Cryonicists are often dismissed as wasteful, selfish, and narcissistic, and the practice itself is often viewed as an eccentric indulgence for wealthy people with a profound fear of death. And genuine concern exists about the feasibility and viability of cryonics. But as more and more families take the leap into the frozen unknown, there are practical concerns—legal rights, money, consent. And lurking beneath the surface, there is a different fear—that cryonics might just actually work and that signing up for cryonics might be the most insanely rational decision you will ever make.”

In a vat of liquid nitrogen on storage platform 17, the youngest person ever to be put into cryogenic storage has been waiting for the future for one year and eight months.

Continue reading “Generation Cryo: Fighting Death in the Frozen Unknown” »

Bioquark, Inc., (http://www.bioquark.com) a life sciences company focused on the development of novel, natural bio-products for health, wellness and rejuvenation, has entered a collaboration whereby Forest Organics LLC & I-Beauty Charm LLC, a unique, integrated facial and body cosmetology facility, and their state-licensed, highly skilled skin care specialists, will be utilizing novel, natural Bioquantine™ extract complexes as part of their spa procedures, as well as providing consumer access to a range of proprietary skin care products (http://www.forestorganics.life).

“We are very excited about this first company collaboration in the area of beauty care and cosmetology,” said Ira S. Pastor, CEO, Bioquark Inc. “It is another step forward towards the wide applicability of our natural combinatorial bio-products, across a broad range of health and wellness segments, as well as future franchise opportunities.”

The integrated Forest Organics LLC & I-Beauty Charm LLC model was conceived by local Tampa business women, Nadia Goetzinger and Tatyana Reshetnikova, to offer a new generation of products and services related to skin beautification and rejuvenation.

Continue reading “Bioquark Inc. Announces Commercial Cosmetology Relationship with Forest Organics LLC & I-Beauty Charm LLC” »

A daily 7.5g bar of the chocolate can change the underlying skin stucture of a 50 year old to that of someone in their 30s, say developers.

It has officially been one year since I volunteered to take the first gene therapy to treat biological aging. It has been an amazing year! It began with a great deal of excitement in the weeks leading up to taking the treatment. The excitement of treatment day was followed by months of anticipation before the letdown of not magically reversing visual aging and becoming a 20-year-old biologically again. Even so, the year has been filled with energizing information gleaned from every additional molecular biomarker test that we have done. In this post, I will try to summarize my feelings on several topics as they have evolved throughout the year.

First in Human Use

Being the first person to use any new medical treatment is a complicated endeavor. It is infinitely more complicated when we don’t know the possible outcomes, the perfect dosage, the regimen, or the optimal delivery method. With all of these uncertainties, one is constantly aware that all the excitement and hopes could be squelched in moments. For the same reasons, every small success seems unbelievable, even though they are the results we wanted.

Continue reading “One Year Anniversary of BioViva’s Gene Therapy Against Human Aging” »

Detailed commentary on the new SENS Research videos about aging and rejuvenation biotechnology.

The SENS Research Foundation has assembled a set of narrated cellular biochemistry animations that serve as an introduction to the various distinct projects that make up the field of rejuvenation biotechnology. The videos outline the forms of cell and tissue damage that are the root cause of aging and age-related disease, as well as the classes of therapy that could, once constructed, either repair that damage or bypass it entirely. Since aging is exactly an accumulation of damage and the consequences of that damage, repair of the damage is the basis for rejuvenation, the reversal and prevention of degenerative aging and all age-related disease. The goal for the near future is to align ever more of the research community and its funding institutions with this goal, and make real progress towards bringing an end to the pain, suffering, and disease of aging.

Introducing SENS — Metabolism, Damage, Pathology

Continue reading “A Visual Introduction to SENS Rejuvenation Research” »

Something like this…How can we extend sex appeal?

Gyms and beauty salons are in charge of this question now. There is some success, but it’s mostly superficial. Plastic surgery only masks, but doesn’t delay the processes of aging.

Expanding sex appeal is a complex task. Its aspects include both beauty and the activity of the brain. To be sexually attractive we have to be smart and fun. One cannot solve the problem of dementia with makeup.

Continue reading “Let’s formulate the task of life extension slightly differently” »

Scientists have completed reprogramming DNA on the largest scale ever, making the concept of superhumans a reality while advancing Singularity.

Cloned embryo.

Most of us like the idea of superpowers. Though we may never have the strength of Superman, we could be made stronger, faster, and even better-looking, with total control over our genome, or genetic makeup. What about becoming disease-resistant, weight gain resistant, and even slowing down the aging process? This might be possible in decades to come, as geneticists are now getting ever closer to, not just removing and replacing genes, but rewriting entire genomes. It sounds like the realm of science fiction. Yet, consider that geneticists at Harvard recently recoded the genome of a synthetic E. coli bacteria. Prof. George Church and colleagues conducted the study.

Continue reading “Programmable Biology Has Begun” »

Are you an avid supporter of aging research and a keen longevity activist?
The Biogerontology Research Foundation is offering select summer internships for talented individuals. You’d join a passionate and supportive team in researching diagnostic, prognostic, and therapeutic strategies; advising a panel of investors in developing a roadmap to promote longevity science and related technologies across the globe.

The advertised positions are 3 month internships, with the possibility of continuing afterwards. Free accommodation will be provided for in London, alongside a negotiable salary.

The Biogerontology Research Foundation is a UK based think tank dedicated to aging research and accelerating its application worldwide.

Continue reading “Aging Research Internships Available 4” »

A good summary article about the MitoSENS AMA on Reddit Futurology yesterday.

Aubrey de Grey, who should need little introduction here, is cofounder of the SENS Research Foundation, while Matthew O’Connor leads the foundation’s in-house research efforts. O’Connor’s focus is on the allotopic expression of mitochondrial genes, the complicated form of gene therapy needed to copy versions of these genes from the vulnerable mitochondrial genome into the much more secure nuclear genome, but altered in such a way that the resulting proteins can find their way back to the mitochondria where they are needed. Earlier today de Grey and O’Connor stopped by /r/futurology at Reddit to answer questions on this and other SENS rejuvenation research initiatives. One of the many benefits brought by this modern age of near zero cost communication is the way in which the barrier between researchers, supporters, and the public at large has faded to the point of non-existence. Any interested party can in a few minutes find out who is working in any specific areas of interest and reach out with questions or offers of support. Any researcher can find out where the interested parties congregate to talk about their research and join in. That was science fiction just a few decades ago. The world moves at a fast pace.

Once allotopic expression of the thirteen crucial mitochondrial genes involved in oxidative phosphorylation is realized, undergoing this gene therapy will ensure that the accumulation of mitochondrial DNA damage that occurs over the years no longer contributes to degenerative aging as it does today. It will be an actual, working narrowly focused rejuvenation therapy. As an incidental benefit, this technology will also provide cures for a range of inherited mitochondrial diseases. This work has been underway both at the SENS Research Foundation and in allied labs for some years now, and the biotech company Gensight has been founded on success in allotopic expression of the gene ND4. The SENS Research Foundation in-house team recently achieved success for the mitochondrial genes ATP6 and ATP8, and had a paper accepted by a noted journal, which all in all is a great step forward in a field that has proven to be quite challenging.

Continue reading “Aubrey de Grey and Matthew O’Connor of the SENS Research Foundation Answer Questions on Mitochondrial Research at /r/futurology” »