In this episode of Lifespan News:
Binary Clock Predicts Biological Age Longevity company funding roundup Lifespan.io just turned 7 CAR T-cell therapy generates lasting remissions in patients with multiple myeloma CBD Reduces Plaque and Improves Cognition in Model of Familial Alzheimer’s.
Might interest some, mentions telomeres.
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Aging is a common factor in many diseases. So, what if it were possible to treat them by acting on the causes of aging or, more specifically, by acting on the shortening of telomeres, the structures that protect chromosomes? This strategy is being pursued by the Telomeres and Telomerase Group of the Spanish National Cancer Research Centre (CNIO), which has already succeeded in curing pulmonary fibrosis and infarctions in mice by lengthening telomeres. Now they take a first step towards doing the same with renal fibrosis by demonstrating that short telomeres are at the origin of this disease, which is also associated with aging.
But such drugs could face a daunting challenge, since aging is not considered a disease. This means the Food and Drug Administration is unlikely to approve a drug for its anti-aging effects, or as a new use for a licensed drug. Also, pharmaceutical companies probably wouldn’t be inclined to develop drugs for that purpose only.
Drugs that can postpone or prevent the onset of debilitating diseases could enhance longevity and provide enormous societal benefits, geroscientists say.
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Continue reading “Why Your Acceptance Of Ageing Is Out-Of-Date Thinking” »
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Papers referenced in the video:
Check out “How Watson Works here.”
Is it possible to live forever by using narrow AI that can perform faster and smarter than humans? Having a doctor give you the correct diagnosis and treatment plan only happens on average, 54% of the time, as the New England Journal of Medicine has pointed out. Having Watson instantly diagnose you with the correct diagnosis and treatment plan 95% of the time will become the new standard. Our crop of new personal medicine products such as continual internal diagnostics, synthetic immune systems, virtual assistants, and regenerative medicine will diagnose and stop sickness from ever occurring while constantly rebuilding and improving body and mind capabilities.
IBM has made a series of Watson computer systems so that any company can raise their industries products and services far beyond our human capability. IBM’s Watson was first featured to the public with its historic Jeopardy win over Ken Jennings and Brad Rutter the best human Jeopardy players. At the time, Watson contained 200 million pages of structured and unstructured content in a ninety server computing system with an analytical software IBM designed called DeepQA. Now, the financial markets, medicine, insurance companies, government, engineering, and customer service call centers are employing (buying) Watson is an artificial intelligence system, that can be specifically tailored to any digitized industry and quickly evolve their industries potential.
Summary: It’s not only our genetics and environment that play a role in aging and longevity, it’s also the random, tiny changes that arise on the cellular level.
Source: USC
A new model of aging takes into account not only genetics and environmental exposures but also the tiny changes that randomly arise at the cellular level.
Earth is destined for disaster. This is a good insurance policy.
In 2013, a cataclysmic meteor the size of a six-story building broke apart above Chelyabinsk, Russia, and the resulting blast was stronger than a nuclear explosion. In 2068, astronomers believe a potentially hazardous “God of Chaos” asteroid could slam into Earth. Both events suggest humans—and every other animal and plant on Earth—are much more susceptible to total annihilation than we think.
Continue reading “Scientists Are Planning to Build Noah’s Ark on the Moon” »
The hematopoietic (blood-forming) stem cells (HSCs) residing in our bone marrow produce all of our blood cells, including key immune cells that protect us from bacteria and viruses. As we age, our HSCs become less efficient and less able to make healthy new blood cells. In a study published online today in Nature, researchers at Albert Einstein College of Medicine have found that this reduction in HSC efficiency is caused in part by the deterioration of chaperone-mediated autophagy (CMA), the housekeeping process that removes damaged proteins and other waste materials that interfere with cells’ ability to function.
“While the aging of HSCs in our bone marrow is inevitable, the good news is that it may be reversible,” said co-study leader Ana Maria Cuervo, M.D., Ph.D., professor of developmental and molecular biology, of anatomy and structural biology, and of medicine, and the Robert and Renée Belfer Chair for the Study of Neurodegenerative Diseases at Einstein. “Our studies in mice suggest that drugs we’ve developed at Einstein can activate CMA and potentially restore the vitality of HSCs in older people.”
