There’s a lot of research on human life extension… but it’s unclear whether or not it’ll actually work. This is a great roundup of the science already available.
Could human life extension lead to you living for 150 years? We review the latest exciting animal and human research studies to find out.
The results of this study demonstrate a clear relationship between psychopathology and rate of aging. Remarkably, this relationship was obvious by the age of 45. By that time, those with the upper 10% of psychopathology factor (p-factor) scores had aged approximately 5.3 more years than those with the lowest 10% of p-factor scores.
Is a history of psychiatric illness associated with more rapid aging?
Given the rate of overweight and obese people in the Western world, there are inevitably lots of fat people interested in life extension. Assuming that weight-loss trends continue with a high failure rate, the majority of fat spanners will not be able to lose and maintain their weight loss through diet and exercise.
This article explores effective life-extension interventions that do not include weight loss for people with an excess of adipose tissue.
Is it possible to be fat and healthy? Is obesity a death sentence? Learn about what the science says about life extension when fat.
Here’s my latest video!
Papers referenced in the video:
Continue reading “Telomere Length: How Does it Compare Against Other Biological Age Metrics?” »
Bill Faloon’s newest Age Reversal Update.
“Our task is to make nature, the blind force of nature, into an instrument of universal resuscitation and to become a union of immortal beings.“
- Nikolai F. Fedorov.
Antiaging expert Aubrey de Grey says there is a 50% chance that we reach longevity escape velocity by 2035.
I now think there is a 50% chance that we will reach longevity escape velocity by 2036. After that point (the “Methuselarity”), those who regularly receive the latest rejuvenation therapies will never suffer from age-related ill-health at any age.
Continue reading “Medicine 2.0 – Successful Repair of Aging Damage” »
Leading biogerontologist João Pedro de Magalhães says that longevity pharmacology has come of age, and discusses rapamycin and Calico.
Dedicated to those who argue that life extension is bad because it will create overpopulation problems. In adittion to the fact that natality rates are dangerously decreasing in some developed countries, this is only one example of changes that may will take place well before life extension may create a problem of such type, if ever.
Plenty, an ag-tech startup in San Francisco co-founded by Nate Storey, has been able to increase its productivity and production quality by using artificial intelligence and its new farming strategy. The company’s farm farms take up only 2 acres yet produce 720 acres worth of fruit and vegetables. In addition to their impressive food production, they also manage the production with robots and artificial intelligence.
Should interest those into links on aging/longevity and neuroscience.
The mammalian center for learning and memory, hippocampus, has a remarkable capacity to generate new neurons throughout life. Newborn neurons are produced by neural stem cells (NSCs) and they are crucial for forming neural circuits required for learning and memory, and mood control. During aging, the number of NSCs declines, leading to decreased neurogenesis and age-associated cognitive decline, anxiety, and depression. Thus, identifying the core molecular machinery responsible for NSC preservation is of fundamental importance if we are to use neurogenesis to halt or reverse hippocampal age-related pathology.
While there are increasing number of tools available to study NSCs and neurogenesis in mouse models, one of the major hurdles in exploring this fundamental biological process in the human brain is the lack of specific NSCs markers amenable for advanced imaging and in vivo analysis. A team of researchers led by Dr. Mirjana Maletić-Savatić, associate professor at Baylor College of Medicine and investigator at the Jan and Dan Duncan Neurological Research Institute at Texas Children’s Hospital, and Dr. Louis Manganas, associate professor at the Stony Brook University, decided to tackle this problem in a rather unusual way. They reasoned that if they could find proteins that are present on the surface of NSCs, then they could eventually make agents to “see” NSCs in the human brain.
Continue reading “A novel marker of adult human neural stem cells discovered” »
Following on in the vein of my recent topics, this week I am looking at mTOR. A crucial protein that performs the function of an enzyme that is critical for day to day function. There are so many terms and words, subjects and strategies, abound, and so many talk in terms where a basic understanding of the subject is necessary to benefit fully, that I decided to create a kind of library, or resource where you can brush up on all the core fundamentals. Should you stimulate mTOR or seek to restrict it? What will happen if I do? Is this a short term strategy or a lifestyle goal? And what is the real state of the science that underpins it all? These are all questions you, or friends, may have, or even may have heard but been unable to answer fully or concisely, hopefully these will help to reduce those issues. Next week I will be looking at its partner in crime, AMPK, together they exist in balance like a playground see-saw… Until then, have an amazing day…
In this video I will look at what mTOR is and how you can harness it to benefit your objectives. By controlling it we can achieve the balance we need which is to grow muscle to stay fit and strong, but also to not burn out too quickly, so we can live a long healthy life, with a long health span. Maximising anti aging to aid in longevity is delicate balance unique to us all and which varies depending on our current goals and objectives.
